What is absorption and what are the factors affecting it in pharmacology?
Understand the Problem
The question asks about absorption in pharmacology and what factors affect it. This involves understanding how drugs enter the bloodstream from the site of administration and what physiological and chemical factors influence this process.
Answer
Drug absorption is the movement of a drug into the bloodstream. It's affected by drug properties and physiological factors.
Drug absorption is the movement of a drug from its administration site into the bloodstream. Factors affecting it include drug properties like size, lipid solubility, and ionization, as well as physiological factors such as route of administration and patient-specific factors.
Answer for screen readers
Drug absorption is the movement of a drug from its administration site into the bloodstream. Factors affecting it include drug properties like size, lipid solubility, and ionization, as well as physiological factors such as route of administration and patient-specific factors.
More Information
The process by which a drug enters the bloodstream is crucial because it determines how much of the administered dose is available to exert its effects in the body. Poor absorption can lead to sub-therapeutic drug levels, while excessive absorption can increase the risk of toxicity.
Tips
A common mistake is to only consider drug-specific factors and forget about patient-specific factors that can significantly alter drug absorption.
Sources
- Drug Absorption - StatPearls - NCBI Bookshelf - ncbi.nlm.nih.gov
- What is Drug Absorption? - News-Medical - news-medical.net
- Drug Absorption - Drugs - Merck Manual Consumer Version - merckmanuals.com
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