What is a transmembrane domain?
Understand the Problem
The question is asking for the definition and understanding of the term 'transmembrane domain', which relates to a key concept in biology, particularly in the study of cell membranes and membrane proteins.
Answer
A region of a protein that spans the cell membrane.
A transmembrane domain (TMD) is a region of a protein that spans the cell membrane, typically consisting of hydrophobic alpha-helices or beta-barrels.
Answer for screen readers
A transmembrane domain (TMD) is a region of a protein that spans the cell membrane, typically consisting of hydrophobic alpha-helices or beta-barrels.
More Information
Transmembrane domains are important for the proper function and localization of integral membrane proteins. They usually contain hydrophobic amino acids that interact with the lipid bilayer.
Sources
- Transmembrane domain - Wikipedia - en.wikipedia.org
- Transmembrane Domain - an overview | ScienceDirect Topics - sciencedirect.com
- Transmembrane Domain - an overview | ScienceDirect Topics - sciencedirect.com
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