Infants diagnosed with Cri-du-chat Syndrome typically exhibit a distinctive high-pitched cry. Which chromosomal abnormality is directly responsible for this syndrome?
Understand the Problem
The question is concerned with Cri-du-chat Syndrome and its genetic cause. It asks you to identify the specific chromosomal abnormality that directly leads to this syndrome. You need to know the genetic basis of Cri-du-chat Syndrome to answer correctly.
Answer
The chromosomal abnormality responsible for Cri-du-chat syndrome is a deletion on the short arm of chromosome 5 (5p-).
Cri-du-chat syndrome is caused by a deletion of the short arm (p arm) of chromosome 5. This is also written as 5p-.
Answer for screen readers
Cri-du-chat syndrome is caused by a deletion of the short arm (p arm) of chromosome 5. This is also written as 5p-.
More Information
Cri-du-chat syndrome is a rare genetic disorder. It is estimated to occur in 1 in 20,000 to 1 in 50,000 newborns.
Tips
It is important to remember that Cri-du-chat syndrome is specifically associated with chromosome 5.
Sources
- Cri-du-chat syndrome - Better Health Channel - betterhealth.vic.gov.au
- Cri-du-chat syndrome: Symptoms, causes, and treatment - medicalnewstoday.com
- Cri Du Chat Syndrome - StatPearls - NCBI Bookshelf - ncbi.nlm.nih.gov
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