How does methylation of cytosine in DNA typically affect gene activity?

Understand the Problem

The question is asking about the effects of methylation of cytosine in DNA on gene activity. It presents multiple-choice options regarding how this biochemical process influences whether genes are activated or silenced. The focus is specifically on the role of methylation in relation to CpG islands and overall gene expression.

Answer

Cytosine methylation typically inhibits gene activity by repressing transcription.

Methylation of cytosine in DNA typically inhibits gene activity by repressing transcription. It prevents transcription factors from binding by making the chromatin structure less accessible.

Answer for screen readers

Methylation of cytosine in DNA typically inhibits gene activity by repressing transcription. It prevents transcription factors from binding by making the chromatin structure less accessible.

More Information

DNA methylation is an epigenetic mechanism that cells use to control gene expression. It is crucial for development and differentiation. The addition of methyl groups to cytosine can prevent transcription factors from binding to the DNA, thereby blocking transcription.

Tips

A common mistake is forgetting that methylation typically represses gene expression when occurring in promoter regions, rather than activating it.

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