Consider an mRNA sequence: 5'-AUGCGUUAGCCGA-3'. If a ribosome begins translation at the start codon (AUG), what is the sequence of the first three amino acids incorporated into the... Consider an mRNA sequence: 5'-AUGCGUUAGCCGA-3'. If a ribosome begins translation at the start codon (AUG), what is the sequence of the first three amino acids incorporated into the polypeptide, assuming no additional information is given?
Understand the Problem
The question asks to determine the first three amino acids of a polypeptide chain, given an mRNA sequence and the start codon. This requires translating the mRNA sequence into an amino acid sequence, using a codon table and remembering that translation starts at AUG.
Answer
Met-Arg-Leu
The mRNA sequence 5'-AUGCGUUAGCCGA-3' translates to the amino acid sequence: Methionine-Arginine-Leucine (Met-Arg-Leu).
Answer for screen readers
The mRNA sequence 5'-AUGCGUUAGCCGA-3' translates to the amino acid sequence: Methionine-Arginine-Leucine (Met-Arg-Leu).
More Information
Translation is the process where the genetic code in mRNA is decoded to produce a specific sequence of amino acids in a polypeptide chain. This process begins with the start codon (AUG) and continues until a stop codon is encountered.
Tips
A common mistake is not knowing the start codon (AUG) which codes for methionine (Met). Also, you must read the codons in the correct order. Finally, remember to use a codon table to accurately translate each three-nucleotide sequence into its corresponding amino acid.
Sources
- Stages of translation (article) | Khan Academy - khanacademy.org
- Consider translation of the following mRNA sequence:5 - Pearson - pearson.com
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