BIOMEDICAL RESEARCH Basic Research Applied Research Clinical Research Research Team Principal investigator Facility Design Animal rooms Rooms designed to maintain consistent enviro... BIOMEDICAL RESEARCH Basic Research Applied Research Clinical Research Research Team Principal investigator Facility Design Animal rooms Rooms designed to maintain consistent environmental parameters depending on the species. Surgical site Used for preparation, performance of surgical procedures. Cage-washing rooms Separate area from the animal room to minimize the spread of disease, used to wash cages and supplies. Laboratories Personnel areas Receiving and storage areas Types of Facilities Conventional Facility Animal rooms open directly onto a central corridor. Double-corridor facility Unilateral flow clean with clean and dirty to dirty. Less possibility of cross-contamination. Barrier facility Used to house germ-free animals, staff shower in, wear sterile clothing. Sterilized food, water, bedding, cages. Filter air. Anything comes in. Containment facility Used to house animals with infectious or zoonotic diseases, staff need to shower before leaving the facility, use disposable clothing. Anything comes out. Environmental Temperature Humidity Ventilation Air pressure Illumination Noise Primary Enclosures Caging Types of caging Material: Stainless steel Strongest, smooth, rust-free, resistance to chemicals. Expensive, might produce microenvironments. Aluminum Lightweight material, less durable, easily damaged by chemicals. Plastic Less expensive, high impact strength, high heat resistance, high chemical resistance. Polycarbonate-clear Polypropylene-opaque Shoebox Solid bottom cages, plastic and flat filter, easily stackable. Usually used for rats, mice, and small rodents. Suspended Racks that hold mesh-bottom cages that slide in and out of the rack. Access to the animal only from the top of the cage. Good ventilation but poor control of microenvironments. Metabolism Used to collect urine and feces, food and water is located outside of the cage and bedding is absent. Transportation Caged on wheels, animals stay short periods of time. Pens and runs Used for house dogs, sheep, goats, and farm animals. Activity Inhalation Recovery Space Social environments Environmental enrichment Feeding and watering device Facility Administration Animal acquisition Quality assurance Facility security Occupational safety and health Classes of Research animals Conventional Animals with undefined or unknown microflora Defined flora animals Axenic (without stranger) germ-free, no evidence of microorganisms Gnotobiotic: animals with well-defined microflora Specific pathogen-free: free of certain pathogens, yet undefined microflora. Major subgroups of Mammals Order Rodentia Rats Mice Hamsters Gerbils Guinea pigs Order Mustelidae Ferrets Lagomorpha rabbits Animal dealers must be licensed by the USDA and adhere to AWA standards of care.
Understand the Problem
The question appears to be a collection of terms and categories related to biomedical research and animal facility design. It outlines various types of research, facility designs, caging materials, environmental parameters, and classes of research animals alongside associated care standards.
Answer
The search results describe various biomedical research facilities and components.
The search results provide detailed information on different types of biomedical research facilities, such as conventional, double-corridor, barrier, and containment facilities, and describe various components like animal rooms, surgical sites, and cage-washing rooms.
Answer for screen readers
The search results provide detailed information on different types of biomedical research facilities, such as conventional, double-corridor, barrier, and containment facilities, and describe various components like animal rooms, surgical sites, and cage-washing rooms.
More Information
The information outlines how different facilities are designed to accommodate specific research needs, such as minimizing contamination, controlling environmental factors, and ensuring occupational safety.
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