Aneuploids result from gametes that lack or have gained one or more chromosomes, the product of nondisjunction?

Understand the Problem

The question asks about the cause of aneuploidy, specifically what process leads to gametes with missing or extra chromosomes.

Answer

True. Aneuploids result from gametes with extra or missing chromosomes due to nondisjunction.

Aneuploids indeed result from gametes that have either gained or lost one or more chromosomes due to nondisjunction during meiosis or mitosis.

Answer for screen readers

Aneuploids indeed result from gametes that have either gained or lost one or more chromosomes due to nondisjunction during meiosis or mitosis.

More Information

Nondisjunction is the failure of chromosomes to separate properly during cell division. This can occur in meiosis I or II (in the formation of sperm and egg cells) or during mitosis. When nondisjunction happens, some gametes end up with an extra chromosome, while others are missing a chromosome. If these atypical gametes participate in fertilization, they can produce aneuploid offspring.

Tips

A common mistake is thinking aneuploidy only occurs in meiosis. While more common in meiosis, nondisjunction can happen during mitosis as well.

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