A 35-year-old woman presents to the Emergency Department with fever and short breath for 2 days. She is a known rheumatoid arthritis patient on hydroxychloroquine daily. Examinatio... A 35-year-old woman presents to the Emergency Department with fever and short breath for 2 days. She is a known rheumatoid arthritis patient on hydroxychloroquine daily. Examination reveals crepitations at the right lower lung. Renal and liver function are normal. She was treated with cefuroxime with resultant significant improvement. However, renal function is deteriorating. Which of the following is the most likely cause of kidney function deterioration? A. Renal vasculitis B. Acute interstitial nephritis C. Prerenal acute kidney failure D. Immune complex glomerulonephritis

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Understand the Problem

The question is asking for the identification of the most likely cause of kidney function deterioration in a specific clinical scenario involving a patient with rheumatoid arthritis and ongoing treatment. It requires knowledge of possible renal complications and their associations with medication and underlying conditions.

Answer

B. Acute interstitial nephritis

The final answer is B. Acute interstitial nephritis.

Answer for screen readers

The final answer is B. Acute interstitial nephritis.

More Information

Acute interstitial nephritis is a typical cause of kidney dysfunction due to an allergic reaction or immune response to certain medications, such as antibiotics like cefuroxime.

Tips

A common mistake is to overlook the potential adverse reactions antibiotics can cause, especially regarding the kidneys.

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