A 10-year-old patient presents with a 3-day history of yellow discoloration of the sclera, anorexia and abdominal pain (see lab results). Test Result Normal Values Indirect bilirub... A 10-year-old patient presents with a 3-day history of yellow discoloration of the sclera, anorexia and abdominal pain (see lab results). Test Result Normal Values Indirect bilirubin 140 <19 mol/L Total bilirubin 260 <20.5 mol/L Albumin 40 36-52 g/L Total Proteins 76 56-80 g/L Alanine aminotransferase 878 10-35 U/L Aspartate aminotransferase 1005 12-40 IU/L Which of the following is the most likely diagnosis? A. Gilbert's syndrome B Infective hepatitis C.Obstructive jaundice D. Acute pancreatitis
Understand the Problem
The question presents a case study of a 10-year-old patient with symptoms and lab results indicative of a liver condition. It requires you to analyze the provided information (scleral discoloration, anorexia, abdominal pain, and elevated bilirubin and liver enzyme levels) to determine the most likely diagnosis from the given options, it appears the patient is suffering from infective hepatitis.
Answer
Infective hepatitis.
The most likely diagnosis is infective hepatitis, given the patient's symptoms (yellow discoloration of the sclera, anorexia, and abdominal pain) along with the lab results indicating elevated levels of both indirect and total bilirubin, as well as significantly elevated liver enzymes (ALT and AST).
Answer for screen readers
The most likely diagnosis is infective hepatitis, given the patient's symptoms (yellow discoloration of the sclera, anorexia, and abdominal pain) along with the lab results indicating elevated levels of both indirect and total bilirubin, as well as significantly elevated liver enzymes (ALT and AST).
More Information
The combination of jaundice (yellow sclera), anorexia, abdominal pain, and markedly elevated liver enzymes (ALT and AST) strongly suggests liver inflammation and damage, typical of hepatitis. Elevated bilirubin levels confirm the presence of jaundice.
Tips
A common mistake is to only consider the elevated bilirubin without factoring in other symptoms and lab results like elevated ALT/AST, which are strong indicators of hepatitis.
Sources
- Bilirubin Test: Understanding High vs. Low Levels & Causes - my.clevelandclinic.org
- Jaundice - StatPearls - NCBI Bookshelf - ncbi.nlm.nih.gov
- Bilirubin blood test Information | Mount Sinai - New York - mountsinai.org
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