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Questions and Answers
What is the primary purpose of a topical anesthetic?
What is the primary purpose of a topical anesthetic?
Which type of tissue is known to absorb topical anesthetics the fastest?
Which type of tissue is known to absorb topical anesthetics the fastest?
Which characteristic should a good topical anesthetic possess?
Which characteristic should a good topical anesthetic possess?
What is the most widely used topical anesthetic agent?
What is the most widely used topical anesthetic agent?
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What is a primary drawback of ester anesthetics compared to amide anesthetics?
What is a primary drawback of ester anesthetics compared to amide anesthetics?
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Which of the following forms of topical anesthetics is NOT one of the listed forms?
Which of the following forms of topical anesthetics is NOT one of the listed forms?
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What is the recommended application time for benzocaine to achieve optimum effect?
What is the recommended application time for benzocaine to achieve optimum effect?
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What characteristic distinguishes amide anesthetics from ester anesthetics?
What characteristic distinguishes amide anesthetics from ester anesthetics?
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What is the typical onset time for lidocaine when used as a topical anesthetic?
What is the typical onset time for lidocaine when used as a topical anesthetic?
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Which of the following statements about topical anesthesia is incorrect?
Which of the following statements about topical anesthesia is incorrect?
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What is the duration of effectiveness for lidocaine when used as a topical anesthetic?
What is the duration of effectiveness for lidocaine when used as a topical anesthetic?
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What is a common symptom of an allergic reaction to anesthetics?
What is a common symptom of an allergic reaction to anesthetics?
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Why should lidocaine not be used over a large area?
Why should lidocaine not be used over a large area?
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What is the primary purpose of a bioadhesive patch for topical anesthetics?
What is the primary purpose of a bioadhesive patch for topical anesthetics?
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What is a potential effect of an overdose of local anesthetics?
What is a potential effect of an overdose of local anesthetics?
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Which of the following types of anesthetics has a greater tendency to produce allergic reactions?
Which of the following types of anesthetics has a greater tendency to produce allergic reactions?
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Study Notes
Purpose of Topical Anesthetics
- Induces temporary numbness to sensory nerve endings in surface mucosa.
- Does not impact sensory nerves related to teeth.
- Depth of anesthesia depends on drug absorption, influenced by tissue thickness and keratinization.
Absorption Characteristics
- Vestibular tissues absorb anesthetics quickly.
- Attached gingiva and buccal mucosa have slower absorption rates.
- Skin, lips, and palatal mucosa exhibit high resistance to absorption.
Uses of Topical Anesthetics
- Administered prior to local anesthesia injections.
- Prevents gagging during x-ray exposure and impressions.
- Assists in dental procedures such as probing, scaling, and suture removal.
- Facilitates crown seating and matrix band placement.
- Provides pain relief for localized issues like oral ulcers and injuries.
Characteristics of Effective Topical Anesthetics
- Should produce lasting and effective anesthesia.
- Must be stable in its applied form.
- Anesthetic agent should release easily from preparation upon application.
- Non-irritating to tissues and should not cause hypersensitivity.
- Should not be toxic at required concentrations and should not delay healing.
- Capable of being washed off with water.
Forms of Topical Anesthetics
- Available in various formulations, including ointments, gels, liquids, sprays, oral rinses, and patches.
Components of Anesthetic Agents
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Esters
- First local anesthetic used was cocaine, which had adverse side effects.
- Esters were developed to retain cocaine's properties while reducing side effects.
- Associated with allergic reactions, less effective and shorter acting compared to amides, primarily used for topical applications.
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Amides
- Developed later with a distinct chemical structure.
- Generally lack significant allergic reactions.
- Potential risks include toxicity and drug overdose; cause vasodilation.
Types of Topical Anesthetics
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Benzocaine (Ester)
- Most commonly used, available in various forms.
- Minimal blood absorption; low toxicity potential.
- Onset in 30 seconds, optimum effect in several minutes, duration between 5-15 minutes.
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Tetracaine Hydrochloride (Ester)
- Rapid absorption with high toxicity risk; not recommended for large areas.
- Onset in 2 minutes, duration 20-60 minutes.
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Lidocaine (Amide)
- Rare allergic reactions, unlikely to cause toxicity.
- Onset in 1-2 minutes, maximum effectiveness in 5 minutes, duration of 15 minutes.
- Available as spray, ointment, and transoral patches.
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Lidocaine Transoral Patch
- Bioadhesive design extends duration of contact between anesthetic and tissue.
- Powerful soft tissue anesthesia with minimal pulpal anesthesia.
- Onset takes 2.5 to 5 minutes, maximum effectiveness reached in 15 minutes, lasting 45 minutes post-application.
Topical vs. Injection Anesthesia
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Topical Anesthesia
- Affects gingival sensation; has short duration and slower onset (3-5 minutes).
- Recommended wait time of 5 minutes before starting injections or procedures.
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Injection Anesthesia
- Affects both teeth and gingiva; provides longer duration and faster onset.
Adverse Reactions
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Allergic Responses
- Greater tendency for esters to cause allergies than amides, with symptoms ranging from mild erythema to life-threatening anaphylaxis.
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Overdose Risks
- Occurs from excessive anesthetic spread and rapid absorption, leading to elevated blood levels.
- Symptoms include increased talkativeness, anxiety, elevated pulse, and blood pressure.
Application Technique
- Use a cotton-tipped applicator to gather ointment on gauze.
- Dry the injection site with sterile gauze.
- Position applicator directly on the injection site; use a new applicator for each site.
- Maintain the applicator in place for the manufacturer's recommended time, minimum of 1 minute.
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