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Questions and Answers

Which of the following is a non-invasive test or procedure?

  • Venipuncture
  • Ultrasonography (correct)
  • Angiography
  • Radionuclide studies
  • Which of the following is not a subjective parameter?

  • Pain
  • Indigestion
  • Tinnitus (correct)
  • Anxiety
  • Which one of the following is not an objective parameter?

  • Ejection fraction
  • Vertigo (correct)
  • Hemoglobin
  • Urine output
  • In monitoring patients, which group of patients has limited availability of data?

    <p>Pediatric patients</p> Signup and view all the answers

    Aspirin is typically the drug of choice for which condition?

    <p>Cardiovascular conditions</p> Signup and view all the answers

    What error did the pharmacist commit in recommending a cough suppressant?

    <p>Ignoring patient-specific factors</p> Signup and view all the answers

    Which metallic ion is crucial in the blood clotting process?

    <p>Calcium (Ca)</p> Signup and view all the answers

    Which medication is known to increase the anticoagulant effect of warfarin?

    <p>Aspirin</p> Signup and view all the answers

    Which cells derive from the bone marrow and are responsible for providing humoral immunity?

    <p>B lymphocytes</p> Signup and view all the answers

    What is indicated when Blood Urea Nitrogen levels are above normal values?

    <p>Liver disease</p> Signup and view all the answers

    Which term describes the maximum effect a drug can produce regardless of the dose required?

    <p>Drug efficacy</p> Signup and view all the answers

    What describes the situation when the combined effect of two drugs is greater than the sum of their independent effects?

    <p>Synergism</p> Signup and view all the answers

    Which of the following drugs can induce hemolysis?

    <p>Chloramphenicol</p> Signup and view all the answers

    Which term refers to the likelihood that study results can guide clinical decision making?

    <p>Applicability</p> Signup and view all the answers

    Which enzyme is inactivated by MAO enzymes?

    <p>All of the above</p> Signup and view all the answers

    This metabolic disease results from insufficiency in the enzyme phenylalanine hydroxylase:

    <p>Phenylketonuria</p> Signup and view all the answers

    What factors influence the rate of exchange of drugs from one fluid compartment to another?

    <p>All of the above</p> Signup and view all the answers

    Which method is commonly used to determine the extent of protein binding in vitro?

    <p>All of the above</p> Signup and view all the answers

    What is the primary purpose of cholekinetics?

    <p>To induce gallbladder contractions</p> Signup and view all the answers

    Which substance, when excreted into the sweat, is NOT typically associated?

    <p>Gentamicin</p> Signup and view all the answers

    Why should Diazoxide not be used in a patient with a history of malignant hypertension and recent myocardial infarction?

    <p>It can exacerbate tachycardia</p> Signup and view all the answers

    Which of the following is not a primary treatment option for congestive heart failure?

    <p>Antihistamines</p> Signup and view all the answers

    What is a common precaution for patients on corticosteroid therapy?

    <p>Appetite stimulation</p> Signup and view all the answers

    Which medication should not be taken with Levodopa?

    <p>Pyridoxine</p> Signup and view all the answers

    In the context of gastroenteritis, which of these is not a typical clinical manifestation?

    <p>Night sweats</p> Signup and view all the answers

    Which of the following best describes the action of metoprolol?

    <p>Beta-blocker</p> Signup and view all the answers

    What is a main reason ganglionic blocking agents are not commonly used for hypertension?

    <p>Severe side effects</p> Signup and view all the answers

    Myxedema is a condition related to which of the following states?

    <p>Hypothyroid</p> Signup and view all the answers

    What is a significant potential complication of corticosteroid therapy?

    <p>Cushing's syndrome</p> Signup and view all the answers

    What is the drug of choice for gout that decreases the formation of uric acid by inhibiting xanthine oxidase?

    <p>Allopurinol</p> Signup and view all the answers

    What does bradykinesia refer to?

    <p>A slowness in performing common voluntary movements</p> Signup and view all the answers

    What condition may occur if beta-blockers are abruptly discontinued?

    <p>Reflex tachycardia</p> Signup and view all the answers

    Which of the following has no therapeutic use for the prophylaxis of classic migraine headache?

    <p>Clonidine</p> Signup and view all the answers

    Which term best describes a pattern of effects associated with drug allergy?

    <p>Hypersensitivity</p> Signup and view all the answers

    Which drug class should be used with caution for diabetics with hypertension due to its side effects?

    <p>Noncardioselective beta blockers</p> Signup and view all the answers

    What happens to erythrocytes when the spleen of a person is removed?

    <p>Increased risk of infection</p> Signup and view all the answers

    What laboratory evaluation is typically not associated with hypertension assessment?

    <p>Microscopic examination</p> Signup and view all the answers

    Study Notes

    Non-invasive Tests

    • Ultrasonography is a non-invasive test.
    • Angiography, radionuclide studies and venipuncture are invasive procedures.

    Laboratory Tests for Fungal Skin Infections

    • There is no laboratory test specifically mentioned for fungal skin infections in the provided text.

    Macroscopic Evaluation of Sputum

    • Macroscopic evaluation of sputum includes: color, viscosity, and odor.
    • Gram's stain is a microscopic evaluation technique, not a macroscopic one.

    Subjective Parameters vs. Objective Parameters

    • Subjective parameters are based on patient's feelings and are not measurable, such as anxiety, indigestion, and pain.
    • Objective parameters are measurable and quantifiable, such as hemoglobin, urine output, and ejection fraction.
    • Vertigo is a subjective parameter

    Therapeutic Regimen Selection

    • The text does not specify the steps involved in selecting therapeutic regimens.

    Fundamental Moral Principle in Ethics

    • The text does not mention a specific fundamental moral principle.

    Communication with Hearing-Impaired Elderly Patients

    • The text does not provide information about communication techniques for hearing-impaired elderly patients.

    Monitoring Data Availability

    • The text does not specify which kind of patient has limited monitoring data availability.

    Aspirin's Drug of Choice Use

    • The text does not mention the specific conditions where aspirin is the drug of choice.

    Pharmacist Error

    • The pharmacist's error was recommending a nonprescription cough suppressant without checking the patient's medication profile.

    Metallic Ions in Blood Clotting

    • Calcium (Ca) plays a crucial role in the blood clotting process.

    Endoscopy and Diagnosis

    • Endoscopy can be helpful in diagnosing peptic ulcer disease.

    Life-Threatening Adverse Drug Reactions

    • Most life-threatening adverse drug reactions affect the cardiovascular and respiratory systems.

    Congestive Heart Failure Emergency Treatment

    • Emergency treatment for congestive heart failure includes vasodilators, diuretics, and bed rest.

    Drug Interactions with Propranolol

    • Digoxin, chlorothiazide, and quinidine interact with propranolol.

    Warfarin Anticoagulation

    • Cystitis does not increase the anticoagulant effect of warfarin.

    Immunologic Activity and Antibody Production

    • Lymphocytes play a dominant role in immunologic activity and produce antibodies.
    • B lymphocytes are derived from bone marrow and provide humoral immunity.

    Complete Blood Count

    • A complete blood count (CBC) includes hemoglobin, hematocrit, red blood cell count, white blood cell count, mean cell volume (MCV), mean cell hemoglobin (MCH), and mean cell hemoglobin concentration (MCHC).

    Blood Urea Nitrogen (BUN)

    • Elevated BUN levels can indicate the following conditions: renal disease, dehydration, and gastrointestinal bleeding.
    • BUN is not a reliable indicator of liver disease.

    Drug Efficacy

    • Drug efficacy refers to the maximum effect a drug can produce irrespective of the dose required.

    Applicability of Study Results

    • Applicability is the likelihood that findings from a study are useful in clinical decision-making.

    Drug Interactions

    • Synergism occurs when the combined effect of two drugs is greater than the sum of their individual effects.

    Primary Sources of Drug Information

    • Primary sources of drug information include: medical journals, pharmacy and pharmacology journals, the medical letter.

    Monoamine Oxidase (MAO) Enzymes

    • MAO enzymes inactivate adrenaline, noradrenaline, and serotonin.

    Kernicterus

    • Kernicterus, a drug-induced disorder in neonates, can occur after sulfosoxazole therapy.

    Hemolysis-Inducing Drugs

    • Drugs known to induce hemolysis include: aspirin, probenecid, and chloramphenicol.
    • Arsenicals are not listed as causing hemolysis.

    Monitoring Process

    • The last step in the monitoring process is not specified in the provided text.

    Source of Drug Information

    • Standard pharmacy textbooks are the most appropriate source for questions regarding drug dosage regimens.

    Secondary and Tertiary Literature

    • Secondary and tertiary literature do not include original research articles.

    Phenylketonuria

    • Phenylketonuria (PKU) is a metabolic disorder caused by a deficiency in the enzyme phenylalanine hydroxylase.

    Drug Action

    • Drug action refers to the alteration in a cell's response caused by a drug.

    Drug for Gout

    • Allopurinol is used to manage gout by inhibiting xanthine oxidase, which reduces uric acid production.

    Bradykinesia

    • The slowness in performing voluntary movements like standing or walking is called bradykinesia.

    Sudden Beta-Blocker Discontinuation

    • Discontinuing beta-blockers abruptly can lead to reflex tachycardia.

    Migraine Prevention

    • Lithium does not have any therapeutic use in migraine prevention

    Drug Hypersensitivity

    • Hypersensitivity describes a pattern of effects associated with drug allergy.

    Medication for Tremors in Parkinson's Disease

    • Anticholinergics are used to treat mild Parkinson's disease symptoms, primarily tremors.

    Sulfonamides Adverse Reactions

    • "Gray baby syndrome" is not an adverse reaction to sulfonamides.

    Beta-Blockers in Diabetics with Hypertension

    • Noncardioselective beta-blockers can inhibit the liver's conversion of glycogen to glucose, posing a risk for diabetics with hypertension.

    Symptoms of Diabetes Mellitus

    • Polyneuritis is not a symptom of diabetes mellitus.

    Splenectomy and Erythrocytes

    • The text does not specify what happens to erythrocytes after splenectomy.

    Drugs Contraindicated in Gastric Ulcers

    • Anticholinergics can prolong gastric emptying and are contraindicated in patients with gastric ulcers.

    Methanol Poisoning

    • Methanol, a type of alcohol, can cause blindness.

    Laboratory Evaluation for Hypertension

    • Microscopic examination is not typically used to evaluate hypertension.

    Congestive Heart Failure Emergency Treatment

    • Vasodilators are used in the emergency treatment of congestive heart failure.

    Corticosteroid Therapy Precautions

    • Hyperkalemia (high potassium levels) is not a typical precaution for corticosteroid therapy.

    Levodopa Interactions

    • Pyridoxine (vitamin B6) is not a drug that interacts with levodopa.

    Gastroenteritis Manifestations

    • Night sweats are not a common manifestation of gastroenteritis.

    Schizophrenic Syndrome

    • Schizophrenia is associated with increased dopaminergic activity in the brain.

    Metoprolol's Similarities

    • Metoprolol is pharmacologically similar to propranolol.

    Ganglionic Blocking Agents

    • Ganglionic blocking agents are not widely used as antihypertensive agents due to their significant side effects.

    Patient Hospital Records Ownership

    • Completed patient hospital records are the legal property of the patient.

    First Aid Care

    • In first aid care, priority should be given to ensuring the patient's airway, breathing, and circulation (ABCs).

    Drugs Contraindicated in Allergic Bronchial Asthma

    • Propranolol should not be used in patients with allergic bronchial asthma.

    Valproic Acid and Phenobarbital

    • Valproic acid, when prescribed in addition to Phenobarbital, may increase the concentration of Phenobarbital in the body.

    Corticosteroid Therapy Complications

    • A potential complication of corticosteroid therapy is osteoporosis.

    Hypoprothrombinemia

    • Hypoprothrombinemia is a condition characterized by a deficiency in prothrombin, a clotting factor in the blood.

    Clinical Drug Testing Phase I

    • Phase I of clinical drug testing involves administering the drug to a small number of healthy volunteers to test safety and determine an appropriate dose.

    Myxedema

    • Myxedema is caused by a hypothyroid state, where the thyroid gland does not produce enough thyroid hormone.

    Erythromycin-Induced Hepatitis

    • Erythromycin estolate can cause a reversible cholestatic hepatitis with fever and jaundice, a form of hypersensitivity reaction.

    Nizatidine's Mechanism of Action

    • Nizatidine inhibits gastric acid secretion through its anti-H2 receptor activity.

    Drug Distribution

    • The rate of drug exchange between fluid compartments depends on the following factors: pKa of the drug, pH of the fluid compartment, rate of blood flow.

    Protein Binding Determination

    • Protein binding is determined in vitro using techniques like dialysis, electrophoresis, and molecular filtration.

    Drug Affinity and Distribution

    • The affinity of low molecular weight substances to macromolecules in blood and tissues influences the distribution of the drug throughout the body.

    Bromsulphthalein (BSP)

    • Bromsulphthalein (BSP) is used to assess liver secretory function.

    Biliary Recycling

    • The biliary recycling of drugs is influenced by factors like their molecular size and chemical structure.

    Galenic Forms and Drug Absorption

    • The same dose of active ingredient in different galenic forms (e.g., tablets, capsules) can affect the rate and extent of drug absorption.

    Volume of Distribution

    • A larger volume of distribution indicates that the drug is distributed widely throughout the body.

    Cholekinetics

    • Cholekinetics are substances that stimulate bile flow.

    Sweat Excretion of Drugs

    • Gentamicin is not excreted into sweat.

    Nifedipine and Tachycardia

    • Nifedipine, a calcium channel blocker, is more likely than other calcium channel blockers to cause tachycardia (rapid heartbeat).

    Diazoxide and Malignant Hypertension

    • Diazoxide should not be used in patients with malignant hypertension or in the presence of a recent myocardial infarction due to its potential to worsen these conditions.

    Beta-Agonists

    • The text includes a list of beta-agonists: ephedrine, albuterol, metaproterenol, and isoetherine.

    Frontal Headaches and Medications

    • The physician should review the patient's medications to identify the potential cause of frontal headaches.

    Dose Adjustments

    • Dose adjustments can be necessary based on factors such as age, weight, kidney function, and liver function. The text does not specify a specific set of events requiring dose changes.

    Note: While the text provides some information, it lacks details and explanations. There are gaps in the content, and conclusions are not always clearly drawn.

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