Zofran Drug Card Flashcards

Questions and Answers

What is the generic name of Zofran?

Serotonin receptor antagonist

Zuplenz

Nausea control agent

Ondansetron Hydrochloride (correct)

What is the trade name of Ondansetron?

Simvastatin

Amitriptyline

Phenytoin

Zofran (correct)

What is the class of Ondansetron?

Serotonin receptor antagonist, antiemetic

What is the main action of Ondansetron?

Blocks serotonin receptors in the vagus nerve terminals and small intestine Signup and view all the answers

What are the indications for using Zofran?

Prevention and control of nausea and vomiting, especially during chemo and surgical treatments Signup and view all the answers

Which routes can Zofran be administered?

All of the above Signup and view all the answers

What are the contraindications for using Ondansetron?

Allergy to Ondansetron or other 5-HT3 receptor antagonists, family history of Prolonged QT syndrome Signup and view all the answers

What are some adverse effects of Zofran?

Headache, malaise, wheezing, bronchospasm, AFib, abnormal EKG, Prolonged QT syndrome Signup and view all the answers

What special considerations should be noted for Zofran?

Use caution during pregnancy, may be less effective with anti-seizure drugs Signup and view all the answers

What is the standard dose of Zofran?

4mg Signup and view all the answers

Study Notes

Zofran (Ondansetron Hydrochloride) Overview

Generic name: Ondansetron Hydrochloride
Trade names: Zofran, Zuplenz

Classification and Action

Class: Serotonin receptor antagonist; serves as an antiemetic to prevent nausea and vomiting.
Mechanism: Blocks serotonin receptors in vagus nerve terminals and small intestine, reducing triggers of nausea and vomiting.

Indications for Use

Primarily indicated for prevention and control of nausea and vomiting.
Commonly used in hospital settings for patients undergoing chemotherapy and surgical procedures.

Administration Routes

Can be administered via various routes: IV (intravenous), IM (intramuscular), PO (oral), and SL (sublingual).

Contraindications

Not to be used by individuals with known allergies to Ondansetron or other 5-HT3 receptor antagonists.
History of Prolonged QT syndrome in personal or family history is a contraindication.

Potential Adverse Effects

Commonly reported adverse effects include headache, malaise, wheezing, and bronchospasm.
Serious effects can include AFib (atrial fibrillation), abnormal EKG readings, Prolonged QT Syndrome, ST segment depression, 2nd degree heart block.
Other possible side effects: constipation, diarrhea, hives, and skin rash.

Special Considerations

Pregnant individuals should use caution due to potential risks of birth defects from Ondansetron.
Effectiveness may be diminished when used in conjunction with anti-seizure medications such as phenytoin.

Recommended Dosage

Standard dose: 4 mg.

Description

Explore key concepts about Zofran with these flashcards. Each card provides essential information, including the generic name, trade names, drug classification, and its action mechanism. Perfect for students and healthcare professionals seeking to deepen their understanding of antiemetic medications.