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Questions and Answers

Which antibody has been shown to prolong overall survival in physically fit patients with previously untreated chronic lymphocytic leukemia (CLL)?

  • Obinutuzumab
  • Chlorambucil
  • Rituximab (correct)
  • GA101

What is the primary end point of the study?

  • Response rate
  • Overall survival
  • Adverse events
  • Investigator-assessed progression-free survival (correct)

What is the range of the Cumulative Illness Rating Scale (CIRS)?

  • 0 to 10
  • 0 to 56 (correct)
  • 0 to 20
  • 0 to 40

What is the median age of the patients in the study?

<p>73 years (A)</p> Signup and view all the answers

What is the estimated creatinine clearance of the patients in the study?

<p>50 to 69 ml per minute (C)</p> Signup and view all the answers

Which antibody was investigated in this study as compared to rituximab, each combined with chlorambucil, in patients with previously untreated CLL and coexisting conditions?

<p>Obinutuzumab (B)</p> Signup and view all the answers

What was the primary end point of the study?

<p>Progression-free survival (D)</p> Signup and view all the answers

What was the median age of the patients in the study?

<p>73 years (A)</p> Signup and view all the answers

What was the range of the Cumulative Illness Rating Scale (CIRS)?

<p>0 to 56 (C)</p> Signup and view all the answers

What was the estimated creatinine clearance of the patients in the study?

<p>30 to 69 ml per minute (B)</p> Signup and view all the answers

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