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Questions and Answers

What epithelial structure does the epidermis have?

  • Cuboid
  • Stratified Squamous (correct)
  • Columnar
  • ------------------------
  • What epithelial structure does the liver have?

  • Cuboid (correct)
  • Columnar
  • Stratified squamous
  • --------------------------
  • What epithelial structure does the GI tract have?

  • Cuboid
  • Columnar (correct)
  • Stratified Squamous
  • ----------------------------
  • Na+ Ion channels are on the (insert here) surface

    <p>Apical</p> Signup and view all the answers

    Na+/K+ ATPase are on the (insert here) surface

    <p>Basolateral surface</p> Signup and view all the answers

    What types of folding can epithelial achieve?

    <p>Straight, coiled and branching</p> Signup and view all the answers

    What is an example of polarity with organelles?

    <p>Basal layer of the kidney proximal tubules having mitochondria</p> Signup and view all the answers

    What is microvilli for?

    <p>Increasing SA</p> Signup and view all the answers

    What is cilia for?

    <p>Motility</p> Signup and view all the answers

    What are basal folds for?

    <p>Increase SA</p> Signup and view all the answers

    What is an example that Occludins modulate in tight junctions?

    <p>Paracellular permeability</p> Signup and view all the answers

    What claudin is found in leaky epithelial?

    <p>Claudin 2</p> Signup and view all the answers

    What Claudin is found in the epidermis?

    <p>Claudin 1</p> Signup and view all the answers

    What Claudin is found in the cochlea?

    <p>Claudin 4</p> Signup and view all the answers

    What Claudin is found in the respiratory tract, urinary tract, GI tract?

    <p>Claudin 3</p> Signup and view all the answers

    What are the examples of JAMs (Junction Adhesion Molecules)

    <p>Ig superfamily CAMs, and N-CAMS</p> Signup and view all the answers

    Ig superfamily CAMs are Ca2+ dependent?

    <p>False</p> Signup and view all the answers

    What interactions do Ig Superfamily CAMs do?

    <p>Homophilic and heterophilic interactions</p> Signup and view all the answers

    Examples of such interactions?

    <p>Axon guidance, cell migration</p> Signup and view all the answers

    Ig Superfamily CAMs associated proteins: Receptor Tyrosine (insert here), and Receptor Protein Tyrosine (insert here)

    <p>Kinase, and Phosphatase</p> Signup and view all the answers

    What happens when there is no N-CAM in a mouse?

    <p>Neuronal precursors do not migrate to olfactory bulb, making it smaller</p> Signup and view all the answers

    High sialic acid does what to N-CAMS?

    <p>Gives it low affinity, rearrangement</p> Signup and view all the answers

    Low sialic acid does what to N-CAMs

    <p>High affinity, stable tissues</p> Signup and view all the answers

    Cadherins are ___ dependent, and are _________

    <p>Ca2+, homophobic</p> Signup and view all the answers

    What role do Cadherins have?

    <p>Cell adherence, especially in histology</p> Signup and view all the answers

    What are the non-classical cadherins that are heterophilic?

    <p>Desmogleins and Desmocollins</p> Signup and view all the answers

    What are the non-classical cadherins that make desmosomes appear darker in appearance?

    <p>Plakoglobins and Plakophilins</p> Signup and view all the answers

    What do Catenins do?

    <p>Link cadherins to actin cytoskeleton, and send signals to the nucleus - altering gene expression (B-catenin)</p> Signup and view all the answers

    Integrins - B1 subunit is used where?

    <p>Widespread use</p> Signup and view all the answers

    What is B2 used for?

    <p>White Cells</p> Signup and view all the answers

    What is B3 used for?

    <p>Platalets</p> Signup and view all the answers

    What is B4 used for?

    <p>Intermediate filaments</p> Signup and view all the answers

    What is the permeability of Connexions

    <p>1000Da</p> Signup and view all the answers

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