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Questions and Answers

What are some clinical features of Acute Respiratory Distress Syndrome (ARDS)?

  • Develops within 72 hours of insult (correct)
  • Accumulation of neutrophils (correct)
  • Decreased vascular permeability
  • Increased lung volume

Which histologic characteristic is NOT associated with ARDS?

  • Alveolar edema
  • Epithelial hyperplasia (correct)
  • Accumulation of neutrophils
  • Presence of hyaline membranes lining alveolar ducts

In obstructive airway disease, which of the following characteristics is true?

  • Reduced lung compliance
  • Normal or slightly decreased forced vital capacity (FVC) (correct)
  • Significantly increased expiratory flow rate
  • Decreased resistance in the airways

Which condition is classified under restrictive airway disease?

<p>Acute interstitial lung disease (B)</p> Signup and view all the answers

What is the characteristic change in the FEV1/FVC ratio for obstructive lung diseases?

<p>Characteristically decreased (B)</p> Signup and view all the answers

What is the primary cause of resorption atelectasis?

<p>Obstruction preventing air from reaching distal airways (A)</p> Signup and view all the answers

Which statement about restrictive airway disease is true?

<p>FVC is reduced (A)</p> Signup and view all the answers

How does the synthesis of interleukin 8 (IL-8) affect ARDS?

<p>It promotes endothelial activation (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of acute lung injury?

<p>Increased arterial oxygen pressure (D)</p> Signup and view all the answers

Which condition is primarily associated with compression atelectasis?

<p>Pneumothorax (A)</p> Signup and view all the answers

What does increased vascular permeability result in during ARDS?

<p>Decreased oxygen diffusion (A)</p> Signup and view all the answers

What clinical feature is indicative of acute respiratory distress syndrome (ARDS)?

<p>Refractory hypoxemia despite oxygen therapy (A)</p> Signup and view all the answers

What is the histologic manifestation of acute respiratory distress syndrome (ARDS)?

<p>Diffuse alveolar damage (DAD) (B)</p> Signup and view all the answers

Which of the following conditions can lead to indirect lung injury contributing to ARDS?

<p>Sepsis (C)</p> Signup and view all the answers

What physiological imbalance occurs as a result of atelectasis?

<p>Ventilation-perfusion imbalance (C)</p> Signup and view all the answers

What is a potential consequence of acute respiratory distress syndrome (ARDS)?

<p>Multisystem organ failure (D)</p> Signup and view all the answers

What is the primary characteristic of emphysema?

<p>Permanent enlargement and destruction of air spaces distal to terminal bronchioles (A)</p> Signup and view all the answers

Which type of emphysema primarily affects the central parts of acini and spares distal alveoli?

<p>Centriacinar emphysema (D)</p> Signup and view all the answers

Which condition is characterized as reversible airflow obstruction?

<p>Asthma (B)</p> Signup and view all the answers

What is the leading cause of emphysema in individuals without congenital deficiencies?

<p>Cigarette smoking (D)</p> Signup and view all the answers

Which type of emphysema occurs more commonly in the lower lung zones?

<p>Panacinar emphysema (D)</p> Signup and view all the answers

What triggers the pathological process in emphysema?

<p>Ongoing inflammation from smoking and pollutants (A)</p> Signup and view all the answers

Which type of emphysema is most commonly associated with spontaneous pneumothorax in young adults?

<p>Distal acinar emphysema (C)</p> Signup and view all the answers

What role does α1-antitrypsin play in the context of emphysema?

<p>Acts as an antielastase, protecting lung tissue (A)</p> Signup and view all the answers

What is the first clinical symptom commonly observed in emphysema?

<p>Dyspnea (D)</p> Signup and view all the answers

Which feature is indicative of chronic bronchitis as opposed to emphysema?

<p>Productive cough (A)</p> Signup and view all the answers

Which cytokine is primarily involved in stimulating IgE production in asthma?

<p>IL-4 (C)</p> Signup and view all the answers

What is a common clinical feature associated with the 'blue bloater' phenotype in chronic bronchitis?

<p>Hypercapnia (A)</p> Signup and view all the answers

What is the typical FEV1/FVC ratio in patients with emphysema?

<p>Reduced ratio (C)</p> Signup and view all the answers

Which of the following is NOT a hallmark of asthma?

<p>Persistent productive cough (C)</p> Signup and view all the answers

What mostly precipitates the development of chronic bronchitis?

<p>Environmental irritants (D)</p> Signup and view all the answers

What characterizes the early phase of the asthma response?

<p>Increased mucus production (B)</p> Signup and view all the answers

Which type of asthma is characterized by a Type I IgE-mediated hypersensitivity reaction and is the most common?

<p>Atopic Asthma (D)</p> Signup and view all the answers

Which medication is most commonly associated with drug-induced asthma by inhibiting the cyclooxygenase pathway?

<p>Aspirin (D)</p> Signup and view all the answers

What are the characteristic symptoms of bronchiectasis?

<p>Severe persistent cough with copious purulent sputum (B)</p> Signup and view all the answers

Which of the following is NOT a predisposing condition for bronchiectasis?

<p>Asthma (C)</p> Signup and view all the answers

What is the term for severe asthma that does not respond to therapy and persists for days to weeks?

<p>Status asthmaticus (D)</p> Signup and view all the answers

Which morphological feature is characteristic of bronchiectasis?

<p>Tram track appearance of airways (B)</p> Signup and view all the answers

What type of triggers is typically associated with non-atopic asthma?

<p>Respiratory infections due to viruses (A)</p> Signup and view all the answers

What is a common clinical feature of bronchiectasis that occurs due to pulmonary complications?

<p>Cor pulmonale (D)</p> Signup and view all the answers

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