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Questions and Answers

A patient with a history of heart failure has a CVP reading of 9 mmHg. Which of the following is the MOST appropriate interpretation of this value?

  • The patient likely has hypovolemia and requires immediate fluid resuscitation.
  • The patient's preload is elevated, though a higher CVP reading is frequent in patients with heart failure. (correct)
  • The patient's preload is within the normal range.
  • The patient's elevated CVP is unexpected, irrespective of heart condition.

During the insertion of a pulmonary artery catheter, a nurse observes a change in waveform on the cardiac monitor that indicates the catheter has entered the right ventricle. What should the nurse do NEXT?

  • Document the observation and continue monitoring the patient's vital signs.
  • Confirm the catheter's position with a chest X-ray before proceeding further.
  • Continue advancing the catheter until the waveform indicates entry into the pulmonary artery. (correct)
  • Withdraw the catheter slightly and attempt to re-advance it into the right atrium.

A patient on positive pressure ventilation with PEEP has a pulmonary artery wedge pressure (PAWP) reading. What consideration is MOST important when interpreting the PAWP value?

  • The trend of PAWP values over time provides more clinically relevant information than a single reading. (correct)
  • PAWP is not impacted by positive pressure ventilation or PEEP.
  • The absolute PAWP value is the primary indicator of left ventricular function.
  • PAWP should be assessed only when the mitral valve is closed.

A patient's CVP reading is 1 mmHg. Which of the following conditions might the nurse suspect?

<p>Severe hypovolemia (D)</p> Signup and view all the answers

The physician orders to evaluate the patient's left ventricular function using hemodynamic monitoring. Which parameter would be MOST appropriate for the nurse to assess?

<p>Pulmonary Artery Wedge Pressure (PAWP) (C)</p> Signup and view all the answers

In the context of inflammation and its impact on hemodynamics, which of the following best describes the body's immediate response to substances like histamine released by irritated cells?

<p>Vasodilation, leading to decreased preload and subsequent decrease in cardiac output. (D)</p> Signup and view all the answers

Why are functional hemodynamic indicators increasingly recommended over CVP (central venous pressure) monitoring for guiding fluid therapy?

<p>Mounting evidence suggests CVP is not clinically effective in guiding fluid management, while functional hemodynamic indicators optimize stroke volume. (C)</p> Signup and view all the answers

Although pulmonary artery catheters (PA catheters) provide comprehensive hemodynamic data, their usage has diminished. Which factor primarily contributes to this decline?

<p>Studies have not shown improved outcomes associated with PA catheter use in many patient populations, leading to the exploration of less invasive methods. (A)</p> Signup and view all the answers

A patient presents with hypotension and signs of poor tissue perfusion. Initial assessment suggests a preload issue. If a pulmonary artery catheter is in place, which pressure reading would be MOST helpful in guiding initial fluid resuscitation?

<p>Pulmonary Artery Wedge Pressure (PAWP) (B)</p> Signup and view all the answers

In assessing a patient's hemodynamic profile, which combination of parameters provides the MOST comprehensive overview of the patient's cardiovascular function?

<p>Preload, afterload, and contractility. (B)</p> Signup and view all the answers

Why is Cardiac Index (CI) considered a more individualized measurement than Cardiac Output (CO)?

<p>CI takes into account a patient's body surface area, providing a value relative to their size, whereas CO is an absolute value. (A)</p> Signup and view all the answers

A patient with COPD is likely to have an elevated:

<p>Pulmonary Vascular Resistance (PVR). (C)</p> Signup and view all the answers

A patient presents with a Systemic Vascular Resistance (SVR) of 600 dynes/sec/cm. What physiological condition is most likely indicated by this value?

<p>Significant vasodilation. (B)</p> Signup and view all the answers

If a patient's Mixed Venous Oxygen Saturation (SVO2) is trending downward, what is the most likely explanation?

<p>The patient's tissues are extracting more oxygen than usual. (D)</p> Signup and view all the answers

Patient X has a CO of 5.0 L/min, height of 5' 5" (165 cm) and weight of 180 lbs (82 kg). Which of the following Cardiac Index (CI) values is most likely for this patient?

<p>3.0 L/min/m2 (A)</p> Signup and view all the answers

What is the primary goal of stroke volume optimization techniques in less invasive hemodynamic monitoring?

<p>To optimize fluids to improve preload, stroke volume, and cardiac output. (C)</p> Signup and view all the answers

Based on the information, what is a key reason for the shift towards less invasive hemodynamic monitoring methods?

<p>PA catheters have not been shown to improve patient outcomes and have limitations in assessing volume status. (C)</p> Signup and view all the answers

Which physiological principle is most closely associated with stroke volume optimization?

<p>Frank-Starling's Law of the heart, concerning the relationship between preload and stroke volume. (D)</p> Signup and view all the answers

A patient in NS requires advanced hemodynamic monitoring, and their physician wants to use a Doppler-based method. Based on the content, what consideration should be taken into account?

<p>Doppler-based methods have yet to be widely adopted in NS. (C)</p> Signup and view all the answers

You are caring for a critically ill patient and need to assess their fluid responsiveness. Which of the following is a minimally invasive technique that can be used to estimate this?

<p>Arterial pressure analysis. (D)</p> Signup and view all the answers

A patient develops cardiogenic shock following a massive myocardial infarction. Which percentage of ventricular myocardium damage is MOST likely associated with the development of this condition?

<p>40% or more (C)</p> Signup and view all the answers

A patient is experiencing profound vasodilation leading to compromised tissue perfusion. Which type of shock is MOST likely the cause?

<p>Distributive shock (B)</p> Signup and view all the answers

Which characteristic is COMMON among all types of distributive shock (neurogenic, anaphylactic, and septic)?

<p>Decreased systemic vascular resistance (C)</p> Signup and view all the answers

Following a spinal cord injury, a patient exhibits massive vasodilation and impaired thermoregulation. Which type of shock is the MOST likely cause?

<p>Neurogenic shock (D)</p> Signup and view all the answers

A patient is suspected of experiencing anaphylactic shock. Which physiological response is MOST indicative of this type of shock?

<p>Massive vasodilation due to hypersensitivity reaction (D)</p> Signup and view all the answers

A patient in the progressive stage of shock is exhibiting decreased cellular perfusion. What physiological consequence is MOST likely to occur if this condition is not promptly addressed?

<p>Tissue injury and eventual cell death. (B)</p> Signup and view all the answers

In the context of shock, which factor is the MOST common underlying denominator across all types, regardless of the initiating cause?

<p>Decreased cellular and tissue perfusion. (B)</p> Signup and view all the answers

A critical care nurse is monitoring a patient at risk for shock. Which nursing action is MOST crucial for improving patient survival rates?

<p>Performing accurate and ongoing patient assessments to detect early warning signs. (A)</p> Signup and view all the answers

A patient’s shock is caused by a combination of reduced oxygen delivery, increased oxygen consumption and inability to utilize oxygen. Which intervention would address the MOST comprehensive aspects of this patient's condition?

<p>Focusing on interventions targeted to improve oxygen delivery, decrease oxygen consumption, and enhance oxygen utilization at the cellular level. (A)</p> Signup and view all the answers

Which of the following statements BEST describes the role of critical care nurses in managing patients experiencing shock?

<p>Critical care nurses are in a key position to improve patient survival rates from shock through early detection and management. (D)</p> Signup and view all the answers

A patient in septic shock remains hypotensive despite initial fluid resuscitation. According to the provided information, what is the next appropriate intervention?

<p>Initiate vasopressor therapy (e.g., Norepinephrine/Levophed). (A)</p> Signup and view all the answers

A patient is suspected of having sepsis. Blood cultures, urine culture and wound cultures have been ordered. According to the information provided, what is the ideal timeframe for administering antibiotics?

<p>Within 1 hour of diagnosis. (B)</p> Signup and view all the answers

Which intervention addresses source control in a septic patient with a confirmed central line infection and an infected wound?

<p>Removing the central venous catheter and debriding the infected wound. (B)</p> Signup and view all the answers

During the hyperdynamic phase of septic shock, a patient exhibits an increased cardiac output and decreased SVR. What is the underlying cause of this decreased SVR?

<p>Massive vasodilation. (B)</p> Signup and view all the answers

Which of the following best describes the primary mechanism by which sepsis leads to altered tissue perfusion?

<p>Massive vasodilation and increased cell permeability due to the systemic inflammatory response. (D)</p> Signup and view all the answers

In the progression from sepsis to septic shock, what key physiological change differentiates septic shock and significantly increases mortality?

<p>Profound circulatory and metabolic abnormalities. (A)</p> Signup and view all the answers

A patient in septic shock is exhibiting signs of adrenal insufficiency despite fluid resuscitation and vasopressor support. What adjunctive therapy might be considered based on this information?

<p>Corticosteroid therapy. (B)</p> Signup and view all the answers

Why is the body's initial clotting response considered an important function in the early stages of infection?

<p>To contain the infection and repair damaged tissue. (A)</p> Signup and view all the answers

What is the significance of recognizing and aggressively treating septic shock in its early stages?

<p>To improve patient outcomes and reduce mortality rates. (D)</p> Signup and view all the answers

During sepsis, the body's immune response transitions from localized to systemic. What is the primary implication of this transition?

<p>The inflammatory process affects the entire body, leading to widespread complications. (D)</p> Signup and view all the answers

A patient with a confirmed infection has a temperature of 39°C, a heart rate of 105 bpm, and an altered mental status. According to qSOFA criteria, which of these findings MOST strongly suggests the patient may be developing sepsis?

<p>Altered mental status (B)</p> Signup and view all the answers

During septic shock, widespread vasodilation is triggered by inflammatory mediators. What is the MOST immediate effect of this vasodilation on tissue perfusion?

<p>Decreased blood pressure and reduced oxygen delivery (D)</p> Signup and view all the answers

In a patient experiencing septic shock, increased cell wall permeability contributes to hypovolemia. What physiological mechanism is MOST directly responsible for this?

<p>Fluid shift from the intravascular to the interstitial space (C)</p> Signup and view all the answers

The 'Hour-1 Bundle' for septic shock emphasizes obtaining blood cultures prior to administering antibiotics. What is the PRIMARY rationale for this sequence?

<p>Antibiotics can interfere with accurate identification of the causative organism (D)</p> Signup and view all the answers

During septic shock disseminated intravascular coagulation (DIC) can occur. What is the MOST significant consequence of disseminated intravascular coagulation (DIC) related to perfusion?

<p>Impaired blood flow due to microclot formation (D)</p> Signup and view all the answers

During the MODS phase of septic shock, a patient develops acute kidney injury. Which assessment finding is MOST indicative of this complication?

<p>Elevated blood urea nitrogen (BUN) and creatinine levels. (B)</p> Signup and view all the answers

A patient in the MODS stage of septic shock is exhibiting signs of disseminated intravascular coagulation (DIC). Which laboratory finding is MOST consistent with this condition?

<p>Prolonged prothrombin time (PT) and partial thromboplastin time (PTT). (B)</p> Signup and view all the answers

A patient in the late stages of septic shock is diagnosed with ARDS. Which ventilator strategy is MOST appropriate to minimize further lung injury?

<p>Low tidal volumes with permissive hypercapnia. (B)</p> Signup and view all the answers

During the MODS phase of septic shock, a patient develops hepatic failure. Which sign or symptom is MOST indicative of this complication?

<p>Elevated liver enzymes and jaundice. (A)</p> Signup and view all the answers

A patient in the MODS stage of shock has a pulmonary artery catheter in place. Which set of hemodynamic parameters would MOST likely indicate a patient is experiencing cardiogenic shock?

<p>Decreased cardiac output, increased CVP, and increased SVR. (C)</p> Signup and view all the answers

A patient in septic shock is receiving fluid resuscitation. What assessment finding would indicate that vasopressor support should be initiated?

<p>Persistent hypotension despite fluid boluses (C)</p> Signup and view all the answers

A patient is suspected of having sepsis. Cultures have been ordered. What is the MOST appropriate timeframe for administering broad-spectrum antibiotics?

<p>Within one hour of diagnosis of sepsis (C)</p> Signup and view all the answers

A patient with a central venous catheter develops sepsis, and the catheter is suspected as the source. Besides antibiotics, what intervention should be considered?

<p>Removing the central venous catheter (C)</p> Signup and view all the answers

During the hyperdynamic phase of septic shock, a patient exhibits an elevated cardiac output. What is the primary physiological mechanism contributing to this response?

<p>Massive vasodilation leading to decreased SVR (D)</p> Signup and view all the answers

Which condition is MOST likely associated with the hyperdynamic phase of septic shock?

<p>Hypotension and bounding peripheral pulses (B)</p> Signup and view all the answers

A patient in septic shock is not responding to vasopressors, and their blood pressure remains low. What additional therapy should the nurse anticipate?

<p>Corticosteroid therapy to address potential adrenal insufficiency (A)</p> Signup and view all the answers

Other than cultures and source control, what intervention is important when managing a patient with sepsis?

<p>Glucose control (A)</p> Signup and view all the answers

A patient in septic shock has warm, flushed skin despite a low blood pressure. What best explains these signs and symptoms?

<p>Compensatory vasodilation in response to tissue hypoxia (A)</p> Signup and view all the answers

Which of the following scenarios would MOST likely lead to hypovolemic shock?

<p>Massive gastrointestinal bleed due to a ruptured ulcer. (B)</p> Signup and view all the answers

A patient is in the compensatory stage of shock. Which physiological response is MOST indicative of this stage?

<p>Normal blood pressure maintained by increased heart rate and vasoconstriction. (D)</p> Signup and view all the answers

Distributive shock is characterized by a maldistribution of blood volume. Which hemodynamic parameter is MOST directly affected by this maldistribution?

<p>Systemic vascular resistance (SVR). (A)</p> Signup and view all the answers

A patient with a history of heart failure develops cardiogenic shock after a myocardial infarction. Which intervention would be the MOST appropriate INITIAL step in managing this patient's shock?

<p>Administer medications to improve cardiac contractility and reduce afterload. (A)</p> Signup and view all the answers

A patient with peritonitis is at risk for developing hypovolemic shock due to:

<p>Third spacing of fluid into the peritoneal cavity. (B)</p> Signup and view all the answers

Which of the following conditions is LEAST likely to directly cause hypovolemic shock?

<p>Acute myocardial infarction leading to severe heart failure. (A)</p> Signup and view all the answers

In a patient with septic shock, widespread vasodilation leads to decreased afterload. Which compensatory mechanism would the body INITIALLY employ to maintain cardiac output?

<p>Increasing heart rate and stroke volume. (C)</p> Signup and view all the answers

A patient experiencing anaphylactic shock would exhibit which combination of the following hemodynamic and clinical manifestations?

<p>Decreased SVR, hypotension, and bronchospasm. (B)</p> Signup and view all the answers

In the late stages of septic shock, what hemodynamic parameter is MOST likely to increase significantly from its value in the early stages?

<p>Systemic Vascular Resistance (SVR) (A)</p> Signup and view all the answers

A patient presenting with neurogenic shock is MOST likely to exhibit which of the following hemodynamic profiles?

<p>Decreased RAP, decreased PAWP, and decreased SVR (C)</p> Signup and view all the answers

A patient is suspected of being in the early stages of septic shock. Which hemodynamic parameter would be MOST indicative of this condition?

<p>Normal or Elevated Cardiac Output (CO) (B)</p> Signup and view all the answers

A patient with cardiogenic shock is likely to present with which set of hemodynamic values?

<p>Increased RAP, increased PAWP, decreased CO/CI, increased SVR (B)</p> Signup and view all the answers

In hypovolemic shock resulting from significant hemorrhage, which of the following compensatory mechanisms would you expect to observe?

<p>Increased heart rate and increased systemic vascular resistance (B)</p> Signup and view all the answers

During anaphylactic shock, what is the MOST likely cause of the decreased systemic vascular resistance (SVR)?

<p>Massive vasodilation caused by histamine release (A)</p> Signup and view all the answers

Why are astute observation and assessment skills critical for acute care nurses managing patients at risk for or experiencing shock?

<p>To facilitate early recognition and implementation of appropriate interventions (B)</p> Signup and view all the answers

What is the MOST important initial nursing intervention for a patient exhibiting signs and symptoms of hypovolemic shock?

<p>Initiating fluid resuscitation to increase preload (D)</p> Signup and view all the answers

During the hyperdynamic phase of septic shock, cardiac output may be normal or increased despite depressed myocardial function. Which of the following compensatory mechanisms primarily contributes to this phenomenon?

<p>Reduced systemic vascular resistance (SVR) and afterload due to vasodilation (A)</p> Signup and view all the answers

In the hyperdynamic phase of septic shock, why does the oxygen level in venous blood remain higher than expected despite increased cardiac output and oxygen demand?

<p>Cellular dysfunction preventing adequate oxygen extraction (C)</p> Signup and view all the answers

A patient in the hypodynamic phase of septic shock exhibits decreased circulating volume. How does this impact oxygen levels in venous blood?

<p>Decreases oxygen levels due to poor cardiac output. (B)</p> Signup and view all the answers

A patient in septic shock is in the hyperdynamic phase. What effect does this phase typically have on renal perfusion and urine output?

<p>Increased renal perfusion and urine output due to increased cardiac output, at least temporarily (D)</p> Signup and view all the answers

In the progression of septic shock, what is the likely consequence of the vasoconstriction of the renal bed?

<p>Renal ischemia and predisposition to acute kidney injury (C)</p> Signup and view all the answers

Which set of the following conditions contribute to reduced cardiac output (CO) and cardiac index (CI) during the hypodynamic phase of septic shock?

<p>Profound hypotension, intense vasoconstriction, and decreased venous return to the heart. (B)</p> Signup and view all the answers

A patient in the hypodynamic phase of septic shock has reduced myocardial contractility. Which of the following best describes its effect on cardiac output (CO) and cardiac index (CI)?

<p>Myocardial contractility reduces CO and CI. (A)</p> Signup and view all the answers

Which of the following is the correct sequence of clinical manifestations occurring during septic shock?

<p>Hyperdynamic phase followed by hypodynamic phase. (A)</p> Signup and view all the answers

A patient who experienced a severe allergic reaction is displaying signs of anaphylactic shock. Besides epinephrine, which physiological response is MOST indicative of this type of shock that the nurse should monitor?

<p>Profound vasodilation and decreased systemic vascular resistance (SVR). (C)</p> Signup and view all the answers

After a motor vehicle accident, a patient is diagnosed with a spinal cord injury and is exhibiting signs of neurogenic shock. Which combination of clinical manifestations would the nurse expect to observe?

<p>Hypotension, bradycardia, and warm, dry skin. (C)</p> Signup and view all the answers

A patient is diagnosed with cardiogenic shock following a massive myocardial infarction. What percentage of damage to the left ventricle is MOST likely associated with the development of this condition?

<p>$40%$ (B)</p> Signup and view all the answers

A patient is experiencing profound vasodilation leading to compromised tissue perfusion. Which type of shock is MOST likely indicated by these symptoms?

<p>Distributive shock (C)</p> Signup and view all the answers

What is the underlying mechanism for the decreased systemic vascular resistance (SVR) observed in all types of distributive shock?

<p>Profound vasodilation (B)</p> Signup and view all the answers

A patient who has experienced significant trauma is suspected of being in the early stages of hypovolemic shock. Which of the following assessment findings would be MOST indicative of this early stage?

<p>Tachycardia and narrowed pulse pressure. (B)</p> Signup and view all the answers

Which of the following mechanisms is the MOST likely cause of hypovolemic shock in a patient with severe burns?

<p>Loss of intravascular volume due to increased capillary permeability. (D)</p> Signup and view all the answers

A patient is admitted with peritonitis following a ruptured appendix. Which of the following pathophysiological processes associated with peritonitis is MOST likely to contribute to hypovolemic shock?

<p>Third spacing of fluid into the peritoneal cavity. (C)</p> Signup and view all the answers

A patient in the progressive stage of shock is exhibiting decreased cellular perfusion. What is the MOST likely compensatory mechanism that will be overwhelmed in this stage?

<p>Anaerobic metabolism leading to lactic acid build-up. (C)</p> Signup and view all the answers

A patient with a history of heart failure is admitted with fluid overload and respiratory distress. Which of the following types of shock is MOST likely to develop if the patient's condition worsens?

<p>Cardiogenic shock due to impaired contractility. (D)</p> Signup and view all the answers

A patient in the early stages of hypovolemic shock is receiving isotonic crystalloids for fluid replacement. What is the PRIMARY rationale for using isotonic solutions in this situation?

<p>To expand the intravascular volume without causing a significant fluid shift between the extracellular fluid (ECF) and the cells. (B)</p> Signup and view all the answers

A patient with cardiogenic shock exhibits hypotension and poor tissue perfusion. If a pulmonary artery catheter is in place, which hemodynamic finding would the nurse expect to see?

<p>Elevated pulmonary artery wedge pressure (PAWP). (D)</p> Signup and view all the answers

A patient in hypovolemic shock has received a large volume of crystalloid fluids, but their blood pressure remains low, and oxygen saturation is not improving. Which intervention should the nurse anticipate NEXT?

<p>Administer packed red blood cells to increase oxygen-carrying capacity. (B)</p> Signup and view all the answers

A patient in septic shock is hypotensive despite aggressive fluid resuscitation. According to the guidelines, what should be the next intervention?

<p>Initiate vasopressor therapy (e.g., norepinephrine). (A)</p> Signup and view all the answers

After obtaining initial cultures, what is the recommended timeframe for administering broad-spectrum antibiotics in a patient diagnosed with sepsis?

<p>Preferably within one hour of diagnosis. (D)</p> Signup and view all the answers

A patient in cardiogenic shock is receiving treatment to improve cardiac output and tissue perfusion. Which assessment finding would indicate that the interventions are achieving the desired effect?

<p>Increased urine output and improved mental status. (D)</p> Signup and view all the answers

A patient with suspected hypovolemic shock is being assessed. Which clinical manifestation would suggest the patient is in the LATE stage of shock rather than the early stage?

<p>Clammy, mottled skin (D)</p> Signup and view all the answers

A patient in septic shock has a central venous catheter suspected of being the source of infection. Besides administering antibiotics, what other intervention should be considered?

<p>Removing the infected central venous catheter. (D)</p> Signup and view all the answers

During the hyperdynamic phase of septic shock, a patient exhibits an increased cardiac output and decreased SVR. What is the primary cause of the reduced SVR?

<p>Massive vasodilation due to inflammatory mediators. (D)</p> Signup and view all the answers

A patient in septic shock is not responding adequately to fluid resuscitation and vasopressors, and continues to show signs of adrenal insufficiency. Which adjunctive therapy should the nurse anticipate?

<p>Initiating corticosteroid therapy. (D)</p> Signup and view all the answers

Flashcards

Inflammation-Induced Vasodilation

Dilation of blood vessels due to substances released during inflammation.

Preload

The volume of blood in the ventricles at the end of diastole; affects cardiac output.

Hemodynamic Profile

Monitoring preload, afterload and contractility to assess a patient's condition.

Functional Hemodynamic Indicators

Indicators used to guide fluid therapy and optimize stroke volume.

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Pulmonary Artery Catheter

A catheter used to measure pulmonary artery pressures to assess volume status and heart function.

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Central Venous Pressure (CVP)

Pressure in the right atrium, reflecting preload. Normal range: 2-6 mmHg.

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Right Atrial Pressure (RAP)

Synonymous with CVP, indicating pressure in the right atrium.

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Pulmonary Artery (PA) Catheter

Measures pulmonary artery pressures and provides information about left ventricular end-diastolic pressure (LVEDP)

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Left Ventricular End-Diastolic Pressure (LVEDP)

Pressure in the left ventricle at the end of diastole, indicative of left ventricular function

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Cardiac Output

The amount of blood pumped by the heart per minute. Normal range: 4-8 L/min.

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Cardiac Index (CI)

Cardiac Index (CI) is a personalized measure of cardiac output adjusted for body surface area. Normal range: 2.4-4 L/min/m².

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Pulmonary Vascular Resistance (PVR)

Pulmonary Vascular Resistance (PVR) is the resistance the right ventricle pumps against. Normal PVR: 100-250 dynes/sec/cm.

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Systemic Vascular Resistance (SVR)

Systemic Vascular Resistance (SVR) is a measurement of left ventricular afterload. Normal SVR: 800-1400 dynes/sec/cm.

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Mixed Venous Oxygen Saturation (SvO2)

Mixed Venous Oxygen Saturation (SvO2) measures the balance between oxygen delivery and consumption in the body. Normal SvO2: 60%-80%.

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High SVR Implies...

High SVR indicates vasoconstriction, increasing the resistance the left ventricle must overcome.

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Less Invasive Hemodynamic Monitoring

Monitoring techniques that are less invasive than PA catheters, aiming to optimize stroke volume.

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Frank-Starling Law

A principle where increasing preload enhances stroke volume until a certain point.

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Stroke Volume Optimization

An optimization strategy focusing on increasing the volume of blood pumped with each heartbeat.

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Pulsus Paradoxus

A phenomenon related to blood pressure changes during respiration.

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Passive Leg Raise (PLR)

Raising the patient's legs to simulate a fluid bolus and assess fluid responsiveness.

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Shock

A syndrome resulting in cellular and tissue hypoxia due to reduced oxygen delivery, increased oxygen consumption, or inability to utilize oxygen.

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Cellular/Tissue Hypoxia

Decreased delivery of oxygen to cells and tissues.

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Causes of Shock

Reduced oxygen delivery, increased oxygen consumption, or inability to utilize oxygen.

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Nursing Role in Shock

Early detection of warning signs through accurate and ongoing patient assessment.

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Stages of Shock

If untreated, a patient experiencing shock will pass through four stages.

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Cardiogenic Shock

Shock resulting from impaired cardiac function, often due to significant myocardial damage.

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Distributive Shock

A type of shock caused by widespread vasodilation, leading to decreased tissue perfusion.

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Anaphylactic Shock

A severe, potentially fatal allergic reaction between an antigen and antibody.

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Neurogenic Shock

Shock characterized by massive vasodilation and impaired thermoregulation due to loss of sympathetic innervation.

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Profound Peripheral Vasodilation

Profound vasodilation leading to an increase in the size of the vascular bed and a resulting decreased systemic vascular resistance (afterload).

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Sepsis Definition

A life-threatening organ dysfunction caused by a dysregulated host response to infection.

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Septic Shock Definition

A subset of sepsis with profound circulatory and metabolic abnormalities, leading to increased mortality.

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Septic Shock Characteristics

Massive vasodilation, decreased tissue perfusion, and loss of cellular energy.

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Sepsis Pathophysiology

The body's immune and clotting response becomes excessive and affects the entire body.

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Early Inflammatory Response

Vasodilation and increased cell permeability to bring WBCs to infection.

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Initial Septic Shock Treatment

Administering broad-spectrum antibiotics to combat potential infections.

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Fluid Resuscitation for Perfusion

Counteracting inadequate tissue perfusion by administering fluids at 30 ml/kg.

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Vasopressors in Septic Shock

Used to raise blood pressure that doesn't respond to fluid resuscitation.

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Blood Culture Collection Sites

Blood should be drawn from a peripheral site and any central venous access device.

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Hyperdynamic Phase of Septic Shock

Increased Cardiac Output and Cardiac Index seen in early septic shock due to vasodilation and decreased SVR.

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qSOFA

A rapid assessment tool to identify patients at risk for sepsis, evaluating mental status, systolic blood pressure, and respiratory rate.

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Sepsis Indicators

Temperature >38°C or Respiratory rate >20 breaths per minute or PaCO2 <32 mmHg or WBC >12,000/mm3

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Hour 1-Bundle

Evidence-based interventions for septic shock, started within the first hour of identification.

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Lactate Level

Measure of lactic acid in the blood, indicating tissue hypoxia and anaerobic metabolism.

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Blood Cultures

Collecting blood samples to identify the causative infectious organism before starting antibiotics.

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Four Stages of Shock

The four stages are initial, compensatory, progressive, and refractory.

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Hypovolemic Shock

Occurs when the intravascular volume is depleted.

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Types of Distributive Shock

Anaphylactic, neurogenic, and septic shock.

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Distributive Shock Response

Massive vasodilatory response.

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Hypovolemic Shock Cause

A decrease in circulating blood volume.

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Causes of Hypovolemic Shock

Excessive blood or fluid loss and third spacing.

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Initial Antibiotic Therapy

Administer broad-spectrum antibiotics to combat potential infections.

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Septic Shock Diagnostics

Measures to determine source of infection.

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Infection Source Control

Removing infected devices or tissue.

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Septic Shock: Increased CO and CI

Compensatory responses to vasodilation.

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Multiple Organ Dysfunction Syndrome (MODS)

The final stage of shock where multiple organs begin to fail.

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ARDS in MODS

Acute Respiratory Distress Syndrome; a common complication in MODS, causing severe hypoxemia.

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DIC in MODS

Disseminated Intravascular Coagulation; a condition involving abnormal blood clotting throughout the body.

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Anuria in MODS

Absence of urine output, indicating kidney failure.

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Refractory Hypoxemia

Low blood oxygen levels that don't improve with standard oxygen therapy.

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Determinants of Cardiac Output

Cardiac output is influenced by contractility, preload, afterload, and heart rate.

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Warm Shock Compensation

Reduced SVR and afterload from vasodilation lead to increased cardiac output.

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Cold Phase Septic Shock

Characterized by reduced CO/CI and increased SVR due to hypotension , vasoconstriction, and decreased venous return.

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Oxygen Extraction in Warm Shock

Cells fail to extract oxygen even with increased cardiac output, raising venous blood oxygen levels.

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Oxygen Levels in Cold Shock

Poor cardiac output and decreased circulating volume leads to decrease of oxygen venous blood.

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Renal Perfusion in Warm Shock

Compensatory increased cardiac output maintains renal perfusion temporarily.

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Vasoconstriction in Septic Shock

Vasoconstriction restricts blood flow of the renal bed throughout septic shock.

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Kidney Injury in Septic Shock

Ischemia and microemboli increase, leading to acute kidney injury.

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Septic Shock

Shock caused by a dysregulated response to infection resulting in widespread vasodilation.

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Hypovolemic, Neurogenic, Anaphylactic and Septic shock on RAP

RAP decreases in this type of shock

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Hypovolemic, Cardiogenic, Neurogenic, Anaphylactic and Late Septic shock on CO/CI

CO/CI decreases in this type of shock

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Hypovolemic, Cardiogenic and Late Septic shock on SVR

SVR increases in this type of shock

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Shock Stage Variability

The body's response depends on pre-existing health, event duration, treatment, and underlying cause.

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Importance of Early Recognition

Early detection and intervention can halt the progression of shock.

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Tachycardia in Hypovolemic Shock

Increased heart rate to compensate for reduced blood volume in hypovolemic shock.

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Hypotension in Hypovolemic Shock

Low blood pressure (systolic < 90 mmHg) due to reduced circulating volume.

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Fluid Replacement in Hypovolemic Shock

Isotonic crystalloids initially, followed by colloids, to restore blood volume.

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Early Antibiotic Administration

Administer broad-spectrum antibiotics as soon as possible, ideally within one hour of diagnosis.

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Infection Source Removal

After initial treatment, identify and remove the source of infection, such as catheters or infected tissue.

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Organ Support in Sepsis

Supportive measures like mechanical ventilation or dialysis to maintain organ function during sepsis.

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Hyperdynamic Phase

A temporary increase in cardiac output observed in early septic shock.

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Decreased SVR in Sepsis

Reduced resistance to blood flow in blood vessels due to massive vasodilation during septic shock.

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Decreased Systemic Vascular Resistance (SVR)

Reduced resistance to blood flow in the systemic circulation. Vasodilation and decreased resistance can lead to hypotension and shock.

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Study Notes

Inflammation and Hemodynamics

  • Irritated or inflamed cells release substances affecting blood vessels.
  • These substances include histamine, prostaglandins, and leukotrienes.
  • They cause blood vessels to dilate, bringing more blood to the injured area.
  • Dilation leads to decreased preload, reducing cardiac output.
  • Adequate preload, or volume, is necessary for the body to pump blood and perfuse tissues.

Advanced Hemodynamic Monitoring Overview

  • Advanced hemodynamic monitoring is constantly evolving with scientific and technological advancements.
  • Central venous pressure monitoring (CVP) is a basic method still used in some ICUs.
  • CVP is not the recommended method to guide fluid management.
  • Functional hemodynamic indicators should guide fluid therapy and optimize stroke volume.
  • The unit reviews hemodynamic monitoring principles, including CVPs and pulmonary artery catheters to apply guiding principles in advanced hemodynamic monitoring.

Pulmonary Artery Catheters

  • Pulmonary artery catheter (PA catheter or Swan-Ganz catheter) is decreasing in usage.
  • PA catheters are not associated with improved outcomes in many patient populations.
  • PA catheters measure pulmonary artery pressures.
  • PA catheters provide data on volume status (preload), vascular resistance (afterload), and heart contractility.
  • These measurements create a hemodynamic profile reflecting a patient's condition.
  • Newer, less invasive methods determine fluid responsiveness to improve cardiac output.

Learning Outcomes

  • Apply guiding principles when considering advanced hemodynamic monitoring.
  • Analyze the numerical values of pulmonary artery catheters.
  • Relate interventions to correct hemodynamic instability with advanced monitoring.
  • Discuss how passive leg raising can predict fluid responsiveness.
  • Explore less-invasive hemodynamic monitoring methods.

Guiding Principles for Advanced Hemodynamic Monitoring

  • Before using advanced hemodynamic monitoring: consider whether it will provide additional guidance, and whether it is contraindicated, or risks outweigh benefits.
  • Consider if similar information can be obtained non-invasively.
  • Single pressure readings hold less significance than the pressure trend (increasing, decreasing, or stable).
  • Values must be interpreted in relation to the patient's history, clinical course, and interventions such as mean arterial pressure.
  • Accurate values require leveling the transducer or water manometer to the phlebostatic axis.
  • Learners should memorize CVP and CO parameters.
  • Understand what information pulmonary artery values provide in relation to cardiac function.
  • Expected to interpret pulmonary artery values even when normal ranges are provided on exams.

Central Venous Pressure (CVP)/Right Atrial Pressure (RAP)

  • Monitoring CVP is beneficial when learning to interpret hemodynamic monitoring parameters.
  • CVP and right atrial pressure (RAP) are synonymous because they both indicate the pressure in the right atrium.
  • CVP is used throughout the unit.

Normal CVP Value

  • Normal CVP values range from 2-6 mmHg.
  • The normal value represents preload in a normal, non-diseased heart.
  • Higher CVP readings are common clinically.

Pulmonary Artery Pressures

  • A PA catheter measures pulmonary artery pressures.
  • It measures left ventricle pressure at the end of diastole (LVEDP) when the mitral valve is open.
  • This pressure reading is indicative of left ventricular function.
  • During insertion, the pressures in the right atrium, right ventricle, and pulmonary artery transmit back to a cardiac monitor, which displays a unique waveform and pressure for each area.
  • Positive pressure ventilation and PEEP can increase pulmonary artery pressures. Consistent reading manner and trending are important.

Other Hemodynamic Parameters

Cardiac Output (CO)

  • Normal cardiac output is between 4-8L/min.

Cardiac Index (CI)

  • A highly individualized number based on body surface area.
  • Body surface area is calculated using the patient's height and weight.
  • Normal cardiac index ranges from 2.4-4L/minute.
  • The cardiac index is more useful to determine shock state than cardiac output alone.

Pulmonary Vascular Resistance (PVR)

  • The amount of resistance the right ventricle overcomes during systole.
  • Affected by COPD, septic shock, and pulmonary embolus.
  • Normal PVR: 100-250 dynes/sec/cm.

Systemic Vascular Resistance (SVR)

  • This measures left ventricular afterload.
  • High SVR indicates vasoconstriction.
  • Low SVR indicates vasodilation.
  • Normal SVR: 800-1400 dynes/sec/cm.

Mixed Venous Oxygen Saturation (SVO2)

  • Measures the body's ability to supply oxygen to tissues sufficiently.
  • Normal SVO2: 60%-80%.

PA Catheter Values

  • Right Atrial Pressure (RAP) normal range is 2-6 mmHg and measures preload of the right ventricle.
  • Right Ventricle Pressure (RVP) is normally RVSP: 15-25 mmHg and RVEDP: 2-6 mmHg. The RVP waveform is monitored to ensure catheter has not slipped back into the right ventricle.
  • Pulmonary Artery Pressure (PAP) normal range is PAS: 15-25 mmHg, PAD 8-15 mmHg, and PAM: 10-20 mmHg.
  • Pulmonary Artery Wedge Pressure (PAWP) normal range is 4-12 mmHg and measures preload of the left ventricle

Less Invasive Hemodynamic Monitoring

  • PA catheters are not frequently used because patient outcomes haven't improved.
  • CVP and PA catheters have limitations in determining the volume status of the patient and fluid replacement needs.
  • Less or non-invasive methods measure pressures to reflect volume status currently in use.
  • These methods optimize stroke volume, which relies on pulsus paradoxus and Frank Starling's law.
  • Techniques range from passive leg raises (PLR) to finger-cuff to arterial pressure to transpulmonary thermodilution.

Caring for Hemodynamically Unstable Patients

  • Volume (preload) maintenance matters for cardiac output.
  • Consider if filling pressures are adequate, and review the patient's history for fluid volume deficits or overload.
  • Review heart rate, is it too slow or too fast?
  • Review afterload, is it reduced, is the patient warm?

Advanced Hemodynamic Monitoring Parameter Considerations

  • Decreased Right Ventricular Preload (↓RAP/CVP) can be caused by fluid volume deficit or vasodilation and is treated with volume expanders or vasoconstrictors.
  • Increased Right Ventricular Preload (↑RAP/CVP) can be caused by fluid volume overload or inability of RV to pump fluid, and can be treated with diuretics or inotropic therapy .
  • Decreased Left Ventricular Preload (↓PAWP or est. Using ↓PAD) can be caused by fluid volume deficit or vasodilation and is treated with volume expanders or vasoconstrictors.
  • Increased Left Ventricular Preload (↑PAWP or estimate Using ↑PAD) can be caused by fluid volume overload or inability of LV to pump fluid and is treated with diuretics or inotropic therapy.
  • Increased Right Ventricular Afterload (↑PVR) can be caused by pulmonary hypertension and is treated with pulmonary vasodilators.
  • Increased Left Ventricular Afterload (↑SVR) can be caused by chronic hypertension or SNS compensation and is treated with vasodilators.
  • Decreased Left Ventricular Afterload (↓SVR) can be caused by vasodilation and is treated with peripheral vasoconstrictors.
  • Decreased preload and increased SVR is caused from compensation and is treated by replacing fluids.
  • Decreased SVR + Decreased Preload can stem from a massive inflammatory response and is treated with fluids and vasoconstrictors.
  • Increased Preload and Increased SVR can be cause by SNS compensation for decreased CO and is treated with diuretics and vasodilators.
  • Decreased cardiac output/index (↓contractility) is caused by ACS and is treated with oxygen, vasodilators, and inotropes.

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