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Questions and Answers
What is considered a major factor contributing to the spread of disease?
Which type of carrier transmits a pathogen during the recovery period?
What term describes diseases that humans acquire from animal sources?
What is NOT a characteristic of human reservoirs for disease?
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How does indirect contact transmission occur?
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What is an example of an inanimate reservoir?
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What type of contact transmission does not involve an intermediate host?
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Which of the following vectors is responsible for injecting pathogens?
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What is an endemic disease?
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Which of the following best describes a chronic disease?
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What is the primary difference between a localized infection and a generalized (systemic) infection?
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What characterizes a secondary infection?
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Which stage of disease is characterized by the initial absence of symptoms after infection?
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What is an example of a disease that could be considered a pandemic?
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Which statement describes a carrier?
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What are fomite objects in the context of infectious diseases?
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What is defined as a specific group of signs and symptoms that accompany a particular disease?
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Which type of disease is spread from one person to another through direct or indirect contact?
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Which transmission method involves a microbe being spread in droplet nuclei that travel only a short distance?
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What does the prevalence of a disease refer to?
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What is NOT a cause of disease mentioned in the content?
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Which control measure is essential for managing epidemic diseases?
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What characterizes a contagious disease?
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How is a sporadic disease best defined?
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Study Notes
Factors Contributing to Disease Spread
- Virulence of pathogen: The severity of the disease caused by the pathogen.
- Susceptibility of the population: Individuals' vulnerability to infection based on factors like age, health condition, or immune system.
- Lack of immunization: Absence of protection against specific diseases through vaccination.
- Inadequate sanitation procedures: Poor hygiene leading to disease transmission through contaminated surfaces or water.
- Mode of transmission of the pathogen: The ways in which the disease-causing organism spreads, such as direct contact, airborne particles, or vectors.
Reservoirs of Infection
- Human reservoir: Infected individuals who can transmit the pathogen.
- Animal reservoir: Animals that harbor the pathogen and can transmit it to humans.
- Inanimate reservoir: Non-living objects or substances that serve as a habitat for the pathogen, such as air, soil, or water.
Human Reservoir
- Carrier: A person who harbors a pathogen without displaying symptoms.
- Incubatory carrier: Transmits the pathogen during the incubation period before symptoms manifest.
- Convalescent carrier: Spreads the pathogen during recovery from the disease.
- Active carrier: Fully recovered from the disease but remains infectious for a prolonged period.
- Passive carrier: Carries the pathogen without experiencing the disease.
Animal Reservoir
- Zoonoses: Infectious diseases transmitted from animals to humans.
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Transmission routes:
- Direct contact: Physical contact with infected animals or their waste.
- Inhalation: Breathing in contaminated particles from hides, fur, or feathers.
- Ingestion: Consuming contaminated food or water, or infected animal products.
- Injection: Insect vectors transmitting the pathogen through bites.
Inanimate Reservoir
- Air: Contaminated by dust, smoke, and respiratory secretions.
- Soil: Can harbor pathogens and transmit them through contact or consumption.
- Food: Can become contaminated during handling or storage.
- Water: Can transmit pathogens through ingestion or contact.
- Fomites: Contaminated objects like clothing, bedding, and utensils.
Mode of Transmission
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Contact transmission: Spreading an infectious agent through direct, indirect, or droplet contact.
- Direct contact transmission: Person-to-person transmission via physical contact.
- Indirect contact transmission: Transmission through a contaminated intermediate object.
- Droplet transmission: Spread of microbes in droplets expelled during coughing or sneezing.
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Vector transmission: Disease transmission via animals that carry pathogens from one host to another.
Control of Epidemic Disease
- Reporting communicable diseases: Informing relevant agencies to track and manage outbreaks.
- Public health education: Raising awareness about disease prevention and control measures.
- Identification and elimination of reservoirs: Targeting sources of the pathogen to reduce transmission.
- Isolation of infected individuals: Minimizing spread by restricting contact with others.
- Participation in immunization programs: Increasing population immunity through vaccination.
- Treatment of sick individuals: Providing medical care to limit disease severity and further spread.
Human Microorganism Interaction
- Symptoms: Subjective experiences of disease felt by the patient, like pain or fatigue.
- Signs: Objective evidence of disease observable by a medical professional, like fever or rash.
- Syndrome: A specific set of signs and symptoms associated with a particular disease.
- Incidence: New cases of a disease occurring within a defined population and time period.
- Prevalence: Total number of cases of a disease within a population at a specific time, regardless of when the cases first appeared.
- Disease: A condition in which vital functions are impaired.
Causes of Disease
- Infectious disease: Caused by the growth of pathogens.
- Organ malfunction: Dysfunction of a specific organ, such as hyperthyroidism.
- Vitamin deficiency: Lack of essential vitamins causing disease, like scurvy.
- Allergic response: Hypersensitive reactions triggered by allergens, such as asthma.
- Uncontrolled cell growth: Abnormally rapid cell division leading to cancer.
Medical Microbiology
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Based on behavior within the host:
- Communicable disease: Transmissible directly or indirectly from one host to another.
- Contagious disease: Easily spread from person to person.
- Non-communicable disease: Not transmittable from one host to another.
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Based on occurrence of disease:
- Sporadic disease: Occurs infrequently, usually controlled by immunization and sanitation.
- Endemic disease: Constantly present in a population, often with low numbers.
- Epidemic disease: An unusually high number of cases in a specific area within a short period.
- Pandemic disease: A worldwide epidemic, affecting a large number of people around the globe.
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Based on severity or duration of disease:
- Acute disease: Develops rapidly with a short duration.
- Chronic disease: Onset is slow, with symptoms persisting or recurring over a long time.
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Based on extent of affected host's body:
- Local infection: Microbial invasion limited to a specific area.
- Generalized (systemic) infection: Infection spreading throughout the body or lymph.
- Focal infection: Local infection entering the bloodstream and spreading to other areas.
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Based on state of host's resistance:
- Primary infection: The initial infection causing the initial illness.
- Secondary infection: An infection caused by an opportunistic pathogen after the body's defenses are weakened by a primary infection.
- Subclinical (inapparent) infection: Infection without noticeable symptoms.
Stages of Disease
- Incubation period: Time between initial infection and the first appearance of symptoms.
- Prodromal period: Early, mild symptoms of the disease.
- Period of illness: Progression of signs and symptoms; critical stage.
- Period of decline: Subside of signs and symptoms.
- Period of convalescence: Recovery period.
Isolation Techniques for Laboratory Workers
- Carrier: A person who harbors a pathogen without exhibiting symptoms but can still transmit it.
- Fomite: An inanimate object that can be contaminated with infectious organisms and transmit them.
- Nosocomial infection: An infection acquired in a hospital or healthcare facility.
- Infection: A pathological condition caused by microbial growth in the host.
- Isolation: Restricting the movement or contact of potentially infectious individuals to prevent disease spread.
- Microorganism: A single-celled microscopic organism.
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