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Questions and Answers
What occurs first during systole?
What occurs first during systole?
What is the approximate stroke volume of the heart?
What is the approximate stroke volume of the heart?
During the period of rapid ejection, what percentage of total ejection occurs?
During the period of rapid ejection, what percentage of total ejection occurs?
What is defined as the end-diastolic volume of each ventricle?
What is defined as the end-diastolic volume of each ventricle?
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How is the ejection fraction calculated?
How is the ejection fraction calculated?
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What happens when the left ventricular pressure exceeds aortic pressure?
What happens when the left ventricular pressure exceeds aortic pressure?
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What event primarily causes the P wave on an electrocardiogram?
What event primarily causes the P wave on an electrocardiogram?
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How long does it take for the QRS waves to appear after the onset of the P wave?
How long does it take for the QRS waves to appear after the onset of the P wave?
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What percentage of ventricular filling occurs during diastole before atrial contraction?
What percentage of ventricular filling occurs during diastole before atrial contraction?
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What role do the atria serve during the filling of the ventricles?
What role do the atria serve during the filling of the ventricles?
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What occurs during the period of isovolumic relaxation?
What occurs during the period of isovolumic relaxation?
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What is commonly referred to as the 'atrial kick'?
What is commonly referred to as the 'atrial kick'?
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When do the A-V valves open during the cardiac cycle?
When do the A-V valves open during the cardiac cycle?
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What is the primary cause of symptoms of heart failure during exercise when atrial function is compromised?
What is the primary cause of symptoms of heart failure during exercise when atrial function is compromised?
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Study Notes
Electrocardiogram Overview
- Electrocardiogram (ECG) records heart-generated voltage from the body surface, representing each heartbeat.
- P wave indicates atrial depolarization, leading to atrial contraction.
- QRS complex results from ventricular depolarization, occurring approximately 0.16 seconds after P wave onset, initiating ventricular contraction.
- T wave reflects ventricular repolarization.
Atrial and Ventricular Interaction
- Approximately 80% of ventricular filling occurs during diastole before atrial contraction.
- Atrial contraction contributes the remaining 20% to the ventricles' filling, enhancing pumping effectiveness by 20%.
- Atria dysfunction may lead to significant symptoms like shortness of breath during exercise but usually remain asymptomatic at rest.
Diastole Phases
- At the start of diastole, A-V (atrioventricular) valves are closed; atria fill with blood during systole.
- Isovolumic relaxation occurs as ventricles relax, leading to decreased pressure.
- A-V valves open when ventricular pressure falls below atrial pressure, allowing blood flow into the ventricles.
- Rapid ventricular filling occurs in the first third of diastole, providing most volume, followed by continuous filling.
- Atrial contraction, termed “atrial kick,” happens in the last third of diastole, contributing 20% of ventricular filling.
Systole Mechanism
- Systole begins with ventricular contraction, closing A-V valves and increasing ventricular pressure.
- Isovolumic contraction occurs when no blood is ejected, and fetal volume remains constant while pressure builds.
- Aortic and pulmonary valves open when left ventricular pressure exceeds 80 mm Hg and right ventricular pressure surpasses 8 mm Hg, allowing blood ejection.
- 70% of the total blood ejected from the ventricles occurs during the rapid ejection phase, while 30% happens in the slow ejection phase.
Ventricular Volumes and Ejection Fraction
- End-diastolic volume, the volume in each ventricle at the end of diastole, ranges from 110 to 120 milliliters.
- Stroke volume, the amount of blood ejected per beat, is approximately 70 milliliters.
- End-systolic volume, remaining blood post-ejection, measures around 40 to 50 milliliters.
- Ejection fraction is calculated by the formula: Ejection Fraction = Stroke Volume / End-Diastolic Volume, typically around 60%.
- Stroke volume may be increased by elevating end-diastolic volume and reducing end-systolic volume.
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