Anti Arrhythmics Quiz
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Questions and Answers

Which part of the heart has the slowest conduction velocity?

  • Bundle branches
  • Sinus node
  • Cranial AV node (correct)
  • Ventricle myocytes

    • Which ion current is responsible for phase 0 depolarization in working myocytes and Purkinje fibers?

  • Ca++
  • Na+ (correct)
  • K+
  • HCN

    • What is the absolute refractory period?

  • A period during which a weak stimulus can evoke a response
  • A period during which no stimuli can generate another action potential (correct)
  • A period during which the heart is incapable of responding to the next normal impulse
  • A period during which a more intense stimulus is needed to initiate an action potential

    • What can cause premature contractions in the heart?

    <p>All of the above</p> Signup and view all the answers

    Which phase of the fast action potentials can early afterdepolarizations occur during?

    <p>Phase 2</p> Signup and view all the answers

    What can cause delayed afterdepolarizations during phase 4 of the fast action potentials?

    <p>Ca++ overload of cardiac myocytes</p> Signup and view all the answers

    What is required for reentry tachycardias to occur?

    <p>Areas of slow conduction and unidirectional conduction block</p> Signup and view all the answers

    Which class of antiarrhythmic drugs prevent Ca2+ overload and afterdepolarizations?

    <p>Class Ia</p> Signup and view all the answers

    Which class of antiarrhythmic drugs is not dependent on heart rate and blocks conduction and effective refractory period?

    <p>Class Ic</p> Signup and view all the answers

    Which class of antiarrhythmic drugs acts by inhibiting potassium channels, leading to an increase in action potential duration?

    <p>Class III</p> Signup and view all the answers

    Which class of drugs can reduce the number of atrial excitations that are transmitted into the ventricle, and thus reduce the ventricular rate in patients with atrial fibrillation?

    <p>Class IV</p> Signup and view all the answers

    Which class of antiarrhythmic drugs blocks calcium channels and reduces conduction velocity in the atrioventricular (AV) node?

    <p>Class IV</p> Signup and view all the answers

    Which class of antiarrhythmic drugs primarily block inactivated Na+ channels and reduce action potential duration?

    <p>Class IB</p> Signup and view all the answers

    Which class of antiarrhythmic drugs acts as β-adrenergic receptor blockers and reduces sinus node automaticity?

    <p>Class II</p> Signup and view all the answers

    Which class of antiarrhythmic drugs primarily block open/activated Na+ channels and increase action potential duration?

    <p>Class IA</p> Signup and view all the answers

    Which class of antiarrhythmic drugs primarily block inactivated Na+ channels without effect on action potential duration?

    <p>Class IC</p> Signup and view all the answers

    Which class of drugs can potentially slow ventricular rate in patients with atrial fibrillation/flutter?

    <p>Class II antiarrhythmics</p> Signup and view all the answers

    Which class of drugs can increase the refractory period and potentially break the atrial re-entry tachycardia?

    <p>Class IA antiarrhythmics</p> Signup and view all the answers

    Which class of drugs can reduce the number of atrial excitations that are transmitted into the ventricle, and thus reduce the ventricular rate in patients with atrial fibrillation?

    <p>Class IC antiarrhythmics</p> Signup and view all the answers

    Which class of drugs is indicated for the treatment of atrial fibrillation and can prolong the duration of action potentials?

    <p>Class III antiarrhythmics</p> Signup and view all the answers

    Which of the following factors determine the electrical properties of the heart?

    <p>Conduction velocity, automaticity, refractoriness</p> Signup and view all the answers

    What is the term used to describe the ability of cardiac cells to conduct impulses?

    <p>Conductivity</p> Signup and view all the answers

    Which of the following can lead to ectopic pacemaker activity and reentry tachycardia?

    <p>Conduction velocity, automaticity, refractoriness</p> Signup and view all the answers

    How do the effects of different classes of antiarrhythmic drugs on the electrical properties of the heart relate to their therapeutic uses and potential adverse effects?

    <p>They have a direct relation</p> Signup and view all the answers

    Which class of drugs has been shown to reduce mortality in patients with myocardial infarction?

    <p>Class II</p> Signup and view all the answers

    What are the contraindications for using non-dihydropyridine CCBs?

    <p>All of the above</p> Signup and view all the answers

    Which class of drugs reduces SA nodal rate, AV conduction, and inotropy?

    <p>Class IV</p> Signup and view all the answers

    What are the indications for using verapamil or diltiazem?

    <p>All of the above</p> Signup and view all the answers

    What are the unwanted effects of non-dihydropyridine CCBs?

    <p>Headache, dizziness, minor GI disturbances</p> Signup and view all the answers

    Why should non-dihydropyridine CCBs not be combined with β-blockers?

    <p>They can result in severe cardiosuppression</p> Signup and view all the answers

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