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Questions and Answers

Which side effect is generally transient and often dose related during therapy?

  • Weight gain due to fluid retention
  • Visual field scotoma
  • Fine tremor (correct)
  • Leukocytosis
  • What management strategy could be employed for treating fine tremors?

  • Increase the dose significantly
  • Add a beta blocker (correct)
  • Switch to immediate release formulation
  • Discontinue the treatment immediately
  • Which of the following is a potential long-term side effect that is not dose related?

  • Hypotension
  • Diabetic insipidus
  • Memory problems (correct)
  • Bradycardia
  • What is a common consequence of fluid retention leading to weight gain?

    <p>Decreased metabolic rate due to hypothyroidism</p> Signup and view all the answers

    Which renal side effect is reversible?

    <p>Electrolyte abnormalities</p> Signup and view all the answers

    What is a key effect of valproate as noted in the information provided?

    <p>It has anti-aggressive effects.</p> Signup and view all the answers

    Which of the following is a potential adverse effect of valproate?

    <p>Hepatotoxicity</p> Signup and view all the answers

    How is valproate used in combination with other treatments?

    <p>It can augment antimanic effects when combined with lithium.</p> Signup and view all the answers

    What is the initial dosing guideline for delayed release valproate?

    <p>500 mg BID.</p> Signup and view all the answers

    What is the recommended trough level for valproate?

    <p>50-125 mcg/ml.</p> Signup and view all the answers

    What is a common symptom that Chelsea is experiencing in her current depressive episode?

    <p>Loss of interest in sex</p> Signup and view all the answers

    According to Chelsea's husband, how many periods of depression has Chelsea experienced as an adult?

    <p>Five</p> Signup and view all the answers

    Which of the following best describes the nature of Chelsea's energy levels during her mood episodes?

    <p>Fluctuating between high and low energy</p> Signup and view all the answers

    What behavior has Chelsea adopted that indicates her struggle with depression?

    <p>Watching TV for hours</p> Signup and view all the answers

    What weight change has Chelsea experienced recently, and how has it affected her self-perception?

    <p>Gained six pounds, worsening her self-esteem</p> Signup and view all the answers

    What recurring thought does Chelsea have when she is experiencing her depressive episodes?

    <p>Death seems like a viable option</p> Signup and view all the answers

    How does Chelsea's experience of energy levels during manic episodes contrast with her depressive states?

    <p>Her energy decreases during depressive states</p> Signup and view all the answers

    What is one of the main factors contributing to Chelsea's feelings of depression since starting her new job?

    <p>Concern about her performance as perceived by her boss</p> Signup and view all the answers

    What distinguishes bipolar I disorder from bipolar II disorder?

    <p>Presence of manic episodes</p> Signup and view all the answers

    Which treatment consideration is important for patients with rapid cycling bipolar disorder?

    <p>Combination of two drugs may be required</p> Signup and view all the answers

    What is a common comorbidity in patients with bipolar disorder?

    <p>Substance abuse</p> Signup and view all the answers

    What is the average age at onset for bipolar disorder?

    <p>21 years old</p> Signup and view all the answers

    What symptom is NOT associated with a manic episode?

    <p>Significant memory loss</p> Signup and view all the answers

    What factor is a major predictor of functioning levels in bipolar disorder?

    <p>Adherence to treatment</p> Signup and view all the answers

    What prognosis is typically associated with individuals having rapid cycling bipolar disorder?

    <p>Poorer prognosis</p> Signup and view all the answers

    What is a frequent symptom experienced by patients with mixed features in bipolar disorder?

    <p>Agitation</p> Signup and view all the answers

    What is a common reason for medication non-adherence in bipolar disorder patients?

    <p>Intolerance to side effects</p> Signup and view all the answers

    Which mood episode frequency categorizes rapid cycling in bipolar disorder?

    <p>4 or more episodes per year</p> Signup and view all the answers

    What is the primary reason for avoiding antidepressants in patients with a history of antidepressant-induced mania?

    <p>They may lead to rapid cycling.</p> Signup and view all the answers

    Which of the following combinations is categorized as a common first-line treatment for bipolar disorder?

    <p>Quetiapine + Lithium/Divalproex</p> Signup and view all the answers

    What is recommended if a drug used for acute treatment is continued into the maintenance phase?

    <p>Conduct a dose reduction if necessary.</p> Signup and view all the answers

    Which of the following agents is considered a second-line monotherapy in the treatment of bipolar disorder?

    <p>Carbamazepine</p> Signup and view all the answers

    What should be the approach if therapy with first-line agents is inadequate or not tolerated?

    <p>Add an additional first-line agent.</p> Signup and view all the answers

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