Wound Healing and Tissue Repair - Dr. Natia Bolotashvili Introduction
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Questions and Answers

Which phase of wound healing is characterized by fibroblast activity and production of collagen?

  • Inflammatory phase
  • Remodeling phase
  • Angioneogenesis phase
  • Proliferative phase (correct)
  • Which vitamin is required by fibroblasts to produce collagen during wound healing?

  • Vitamin D
  • Vitamin C (correct)
  • Vitamin E
  • Vitamin A
  • What is the function of platelets during the inflammatory phase of wound healing?

  • Production of collagen
  • Release of cytokines
  • Thrombus formation to limit blood loss (correct)
  • Formation of capillary loops
  • What term describes the initial wound tissue formed during the proliferative phase?

    <p>Granulation tissue</p> Signup and view all the answers

    Which of the following is NOT a common symptom associated with the inflammatory phase of wound healing?

    <p>Itching</p> Signup and view all the answers

    What is the main role of capillary loops in wound healing during the proliferative phase?

    <p>Angioneogenesis</p> Signup and view all the answers

    What is the main characteristic of the remodelling phase of wound healing?

    <p>Decreased wound vascularity</p> Signup and view all the answers

    Which cells are responsible for wound contraction during the remodelling phase?

    <p>Myofibroblasts</p> Signup and view all the answers

    Which type of wound healing aims to reduce the inflammatory and proliferative responses?

    <p>Primary Intention</p> Signup and view all the answers

    What is the recommended time frame for achieving maximal tensile strength in a wound post-injury?

    <p>12 weeks</p> Signup and view all the answers

    What pressure level within muscles indicates compartment syndrome?

    <p>&gt; 30 mmHg</p> Signup and view all the answers

    What is the defining characteristic of pressure sores?

    <p>Prolonged pressure leading to tissue necrosis</p> Signup and view all the answers

    Study Notes

    Wound Healing Phases

    • The proliferative phase is characterized by fibroblast activity and production of collagen.
    • Vitamin C is required by fibroblasts to produce collagen during wound healing.

    Inflammatory Phase

    • Platelets play a crucial role in the inflammatory phase by releasing chemical signals that attract white blood cells to the wound site.
    • Common symptoms associated with the inflammatory phase include pain, redness, swelling, and heat.
    • Itching is NOT a common symptom associated with the inflammatory phase.

    Proliferative Phase

    • The initial wound tissue formed during the proliferative phase is known as granulation tissue.
    • Capillary loops play a crucial role in wound healing during the proliferative phase by providing oxygen and nutrients to the wound site.

    Remodelling Phase

    • The main characteristic of the remodelling phase is the reorganization of collagen fibers to increase wound strength.
    • Myofibroblasts are responsible for wound contraction during the remodelling phase.

    Types of Wound Healing

    • Atraumatic wound healing aims to reduce the inflammatory and proliferative responses.

    Wound Healing Timeline

    • Maximal tensile strength in a wound post-injury is typically achieved within 3-6 months.

    Compartment Syndrome

    • Compartment syndrome is indicated by a pressure level within muscles of greater than 30 mmHg.

    Pressure Sores

    • The defining characteristic of pressure sores is tissue damage caused by constant pressure and lack of movement.

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    Description

    Learn about the mechanism of wound healing and tissue repair as explained by Dr. Natia Bolotashvili. This quiz covers the normal wound healing phases including the inflammatory phase, proliferative phase, and remodelling phase.

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