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Questions and Answers
What are the three characteristics of Whipple's triad?
Low blood glucose level, symptoms of hypoglycemia, symptomatic relief with glucose administration
What does Whipple's triad strongly suggest?
True hypoglycemia
What happens to symptoms in Whipple's triad with the administration of glucose?
Symptomatic relief
What is the significance of low blood glucose level in Whipple's triad?
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How many components make up Whipple's triad?
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Why are most type 1 diabetics dependent on exogenous insulin?
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How should daily basal insulin be provided to type 1 diabetics?
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What is the consequence of discontinuing the morning dose of NPH in type 1 diabetics?
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Why do normal individuals have basal insulin production even without food intake?
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How does the lack of endogenous insulin impact type 1 diabetics?
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Study Notes
Whipple's Triad
- Characterized by three components: low blood glucose level, symptoms of hypoglycemia, and symptomatic relief with glucose administration
- Strongly suggestive of true hypoglycemia
Insulin Production
- Normal individuals have basal insulin production even without food intake
- Type 1 diabetics are dependent on exogenous insulin administration for survival due to lack of endogenous insulin
Insulin Administration
- Daily basal insulin should be provided to type 1 diabetics through:
- Two injections of intermediate acting insulin (NPH, lente)
- One dose of long acting insulin (glargine)
- Discontinuation of morning NPH dose may lead to unwanted evening hyperglycemia
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Description
Test your knowledge on Whipple's triad, which is characterized by a low blood glucose level, symptoms of hypoglycemia, and symptomatic relief with glucose administration. Learn more about the significance of Whipple's triad in diagnosing true hypoglycemia.
