Podcast
Questions and Answers
Topical ______ are effective to decrease inflammation and pruritus in acute and chronic forms of AD.
Topical ______ are effective to decrease inflammation and pruritus in acute and chronic forms of AD.
Corticosteroids
Wet wrap dressings have been shown to reduce ______ and pruritus by serving as a barrier to trauma, cooling the skin and improving penetration of topical therapies.
Wet wrap dressings have been shown to reduce ______ and pruritus by serving as a barrier to trauma, cooling the skin and improving penetration of topical therapies.
inflammation
For mild disease activity, small amounts of ______ in combination with liberal emollient use may be sufficient without producing adverse effects.
For mild disease activity, small amounts of ______ in combination with liberal emollient use may be sufficient without producing adverse effects.
TCS
Wet wrap dressings involve wrapping damp ______ gauze over the affected skin, underneath a layer of dry gauze, usually overnight.
Wet wrap dressings involve wrapping damp ______ gauze over the affected skin, underneath a layer of dry gauze, usually overnight.
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The lowest effective ______ of TCS should be used to avoid irreversible atrophy of the skin.
The lowest effective ______ of TCS should be used to avoid irreversible atrophy of the skin.
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Long-term control of AD can be maintained with twice-weekly use of the ______ or Topical Calcineurin Inhibitors (TCI) to areas previously affected even if they appear normal.
Long-term control of AD can be maintained with twice-weekly use of the ______ or Topical Calcineurin Inhibitors (TCI) to areas previously affected even if they appear normal.
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Epidermal barrier failure is thought to be a main driving force behind subsequent proinflammatory ______ in AD
Epidermal barrier failure is thought to be a main driving force behind subsequent proinflammatory ______ in AD
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Moisturizers are a daily part of skin care in atopic dermatitis and patients often use a variety of products based on ______, skin type, season, and disease state
Moisturizers are a daily part of skin care in atopic dermatitis and patients often use a variety of products based on ______, skin type, season, and disease state
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Regular ______ use has been demonstrated to have a steroid-sparing benefit in managing atopic dermatitis
Regular ______ use has been demonstrated to have a steroid-sparing benefit in managing atopic dermatitis
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Therapy with systemic ______ and anxiolytics are effective through their soporific effects used in the evening
Therapy with systemic ______ and anxiolytics are effective through their soporific effects used in the evening
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Ceramides, hyaluronic acid, dimethicone, licorice extract (glycyrrhetinic acid), and ______ are ingredients in prescription “barrier repair creams”
Ceramides, hyaluronic acid, dimethicone, licorice extract (glycyrrhetinic acid), and ______ are ingredients in prescription “barrier repair creams”
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Relieving the ______ of AD is crucial in preventing the itch-scratching cycle of this disorder
Relieving the ______ of AD is crucial in preventing the itch-scratching cycle of this disorder
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Calcineurin inhibitors prevent T-cell ______, inhibit inflammatory cytokine release and down-regulate high affinity IgE receptor expression on Langerhans cells.
Calcineurin inhibitors prevent T-cell ______, inhibit inflammatory cytokine release and down-regulate high affinity IgE receptor expression on Langerhans cells.
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Topical ______ (ProtopicTM) and pimecrolimus (ElidelTM) have been approved for the treatment of AD in the United States and Europe.
Topical ______ (ProtopicTM) and pimecrolimus (ElidelTM) have been approved for the treatment of AD in the United States and Europe.
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The most common adverse side effect of crisaborole ointment (EucrisaTM) consists of ______ at the site of application.
The most common adverse side effect of crisaborole ointment (EucrisaTM) consists of ______ at the site of application.
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Crisaborole ointment (EucrisaTM) came on the market at the end of 2016 for children over 2 years of age and adults with ______ to moderate AD.
Crisaborole ointment (EucrisaTM) came on the market at the end of 2016 for children over 2 years of age and adults with ______ to moderate AD.
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Crisaborole ointment (EucrisaTM) works by inhibiting ______-4 (PDE-4), preventing breakdown of cyclic AMP (cAMP).
Crisaborole ointment (EucrisaTM) works by inhibiting ______-4 (PDE-4), preventing breakdown of cyclic AMP (cAMP).
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Crisaborole ointment (EucrisaTM) ultimately leads to an increase in ______ cytokines.
Crisaborole ointment (EucrisaTM) ultimately leads to an increase in ______ cytokines.
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