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Questions and Answers
Myelosuppression is more severe with cisplatin compared to other conventional anticancer drugs.
Myelosuppression is more severe with cisplatin compared to other conventional anticancer drugs.
False (B)
Tinnitus and hearing loss are more severe with oxaliplatin than with cisplatin.
Tinnitus and hearing loss are more severe with oxaliplatin than with cisplatin.
False (B)
The distortion caused by cisplatin adduct disrupts the normal covalent bonding between DNA bases.
The distortion caused by cisplatin adduct disrupts the normal covalent bonding between DNA bases.
False (B)
Stalled Replication Machinery due to cisplatin adduct physically aids the enzymes responsible for copying DNA.
Stalled Replication Machinery due to cisplatin adduct physically aids the enzymes responsible for copying DNA.
Mispairing During Replication due to altered base pairing sites can lead to correct base pairing during DNA replication.
Mispairing During Replication due to altered base pairing sites can lead to correct base pairing during DNA replication.
Cells do not initiate DNA repair mechanisms in response to cisplatin-induced DNA damage.
Cells do not initiate DNA repair mechanisms in response to cisplatin-induced DNA damage.
The mechanism leading to Peripheral neuropathy caused by cisplatin is well understood.
The mechanism leading to Peripheral neuropathy caused by cisplatin is well understood.
Chronic neurotoxicity from cisplatin infusion lasts for a few days.
Chronic neurotoxicity from cisplatin infusion lasts for a few days.
Hyperuricemia is primarily caused by neurotoxicity from cisplatin, not nephrotoxicity.
Hyperuricemia is primarily caused by neurotoxicity from cisplatin, not nephrotoxicity.
Preventive measures such as generous hydration with normal saline are unnecessary when using cisplatin.
Preventive measures such as generous hydration with normal saline are unnecessary when using cisplatin.
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