Vulvar Lesions and Vulval Intraepithelial Neoplasia Quiz

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Questions and Answers

Which type of vulval intraepithelial neoplasia (VIN) is now called low grade squamous intraepithelial lesion (LSIL)?

  • Extramammary Paget’s disease
  • High grade squamous intraepithelial lesion (HSIL)
  • Differentiated VIN (dVIN)
  • Usual VIN (correct)

What is the most common type of VIN and is associated with high risk types of HPV?

  • Extramammary Paget’s disease
  • Differentiated VIN (dVIN)
  • Low grade squamous intraepithelial lesion (LSIL)
  • High grade squamous intraepithelial lesion (HSIL) (correct)

In which age group does high grade squamous intraepithelial lesion (HSIL) mainly occur?

  • 50 to 60
  • 30 to 50 (correct)
  • 20 to 30
  • 10 to 20

What is the main risk factor associated with the occurrence of high grade squamous intraepithelial lesion (HSIL)?

<p>Smoking (B)</p> Signup and view all the answers

What may happen to untreated high grade squamous intraepithelial lesion (HSIL) over time?

<p>It may develop into cancer (A)</p> Signup and view all the answers

What typically causes low grade squamous intraepithelial lesion (LSIL)?

<p>High risk types of HPV (B)</p> Signup and view all the answers

Which type of VIN has a higher risk of developing into cancer?

<p>Differentiated VIN (A)</p> Signup and view all the answers

What is the most common histological pattern for vulvar cancer?

<p>Squamous cell carcinoma (SCC) (B)</p> Signup and view all the answers

Which condition is commonly found in women with Differentiated VIN?

<p>Lichen sclerosus (A)</p> Signup and view all the answers

What is the incidence of Extramammary Paget’s disease?

<p>0.53/100,000 (C)</p> Signup and view all the answers

Which type of vulvar cancer is associated with lichen sclerosus?

<p>Warty type (C)</p> Signup and view all the answers

What is the best treatment for Differentiated VIN?

<p>Surgical excision (D)</p> Signup and view all the answers

What is the most common age range for the occurrence of Carcinoma of the vulva?

<p>50-60 years (B)</p> Signup and view all the answers

Which type of vulvar cancer is mainly associated with usual VIN and HPV infection?

<p>Basoloid/warty type (A)</p> Signup and view all the answers

From which glandular epithelium does Extramammary Paget’s disease arise?

<p>Apocrine glandular epithelium (D)</p> Signup and view all the answers

What is the most common symptom in patients with Paget’s disease of the vulva?

<p>Pruritus (D)</p> Signup and view all the answers

Which histologic category of Gestational Trophoblastic Neoplasia (GTN) is characterized by aggressive invasion of the endometrium and myometrium by trophoblastic cells?

<p>Invasive mole (C)</p> Signup and view all the answers

What is the approximate incidence of Gestational Trophoblastic Neoplasia (GTN) in the USA and Europe?

<p>1:50,000 pregnancies (C)</p> Signup and view all the answers

What is a significant risk factor for Gestational Trophoblastic Neoplasia (GTN)?

<p>Age &gt; 40 years (C)</p> Signup and view all the answers

Which criteria are used to diagnose Trophoblastic Neoplasia I?

<p>Sustained HCG level plateau 610% of 4 values over a 3-wk duration (B)</p> Signup and view all the answers

What is a high-risk patient characteristic for Gestational Trophoblastic Neoplasia (GTN)?

<p>Excessively high β-HCG titer prior to evacuation (A)</p> Signup and view all the answers

Which histologic category of GTN is characterized by liver or brain metastasis?

<p>Gestational choriocarcinoma (B)</p> Signup and view all the answers

What is the most common malignant form of gestational trophoblastic neoplasia?

<p>Gestational choriocarcinoma (A)</p> Signup and view all the answers

Which type of gestational trophoblastic neoplasia is characterized by invasion of the myometrium or uterine blood vessels?

<p>Invasive mole (B)</p> Signup and view all the answers

Which form of gestational trophoblastic neoplasia tends to develop early blood-borne systemic metastases?

<p>Gestational choriocarcinoma (C)</p> Signup and view all the answers

What is the characteristic feature of placental-site trophoblastic tumor (PSTT)?

<p>Expansive growth mimicking cervical carcinoma (D)</p> Signup and view all the answers

Which stage of gestational trophoblastic neoplasia involves GTN extending to the lungs, with or without known genital tract involvement?

<p>Stage III (C)</p> Signup and view all the answers

At what age does placental-site trophoblastic tumor (PSTT) typically arise?

<p>&gt;40 years (B)</p> Signup and view all the answers

Which form of gestational trophoblastic neoplasia has a characteristic serum marker of HPL (human placental lactogen)?

<p>Placental site trophoblastic disease (D)</p> Signup and view all the answers

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