Vulvar Lesions and Vulval Intraepithelial Neoplasia Quiz
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Questions and Answers

Which type of vulval intraepithelial neoplasia (VIN) is now called low grade squamous intraepithelial lesion (LSIL)?

  • Extramammary Paget’s disease
  • High grade squamous intraepithelial lesion (HSIL)
  • Differentiated VIN (dVIN)
  • Usual VIN (correct)
  • What is the most common type of VIN and is associated with high risk types of HPV?

  • Extramammary Paget’s disease
  • Differentiated VIN (dVIN)
  • Low grade squamous intraepithelial lesion (LSIL)
  • High grade squamous intraepithelial lesion (HSIL) (correct)
  • In which age group does high grade squamous intraepithelial lesion (HSIL) mainly occur?

  • 50 to 60
  • 30 to 50 (correct)
  • 20 to 30
  • 10 to 20
  • What is the main risk factor associated with the occurrence of high grade squamous intraepithelial lesion (HSIL)?

    <p>Smoking</p> Signup and view all the answers

    What may happen to untreated high grade squamous intraepithelial lesion (HSIL) over time?

    <p>It may develop into cancer</p> Signup and view all the answers

    What typically causes low grade squamous intraepithelial lesion (LSIL)?

    <p>High risk types of HPV</p> Signup and view all the answers

    Which type of VIN has a higher risk of developing into cancer?

    <p>Differentiated VIN</p> Signup and view all the answers

    What is the most common histological pattern for vulvar cancer?

    <p>Squamous cell carcinoma (SCC)</p> Signup and view all the answers

    Which condition is commonly found in women with Differentiated VIN?

    <p>Lichen sclerosus</p> Signup and view all the answers

    What is the incidence of Extramammary Paget’s disease?

    <p>0.53/100,000</p> Signup and view all the answers

    Which type of vulvar cancer is associated with lichen sclerosus?

    <p>Warty type</p> Signup and view all the answers

    What is the best treatment for Differentiated VIN?

    <p>Surgical excision</p> Signup and view all the answers

    What is the most common age range for the occurrence of Carcinoma of the vulva?

    <p>50-60 years</p> Signup and view all the answers

    Which type of vulvar cancer is mainly associated with usual VIN and HPV infection?

    <p>Basoloid/warty type</p> Signup and view all the answers

    From which glandular epithelium does Extramammary Paget’s disease arise?

    <p>Apocrine glandular epithelium</p> Signup and view all the answers

    What is the most common symptom in patients with Paget’s disease of the vulva?

    <p>Pruritus</p> Signup and view all the answers

    Which histologic category of Gestational Trophoblastic Neoplasia (GTN) is characterized by aggressive invasion of the endometrium and myometrium by trophoblastic cells?

    <p>Invasive mole</p> Signup and view all the answers

    What is the approximate incidence of Gestational Trophoblastic Neoplasia (GTN) in the USA and Europe?

    <p>1:50,000 pregnancies</p> Signup and view all the answers

    What is a significant risk factor for Gestational Trophoblastic Neoplasia (GTN)?

    <p>Age &gt; 40 years</p> Signup and view all the answers

    Which criteria are used to diagnose Trophoblastic Neoplasia I?

    <p>Sustained HCG level plateau 610% of 4 values over a 3-wk duration</p> Signup and view all the answers

    What is a high-risk patient characteristic for Gestational Trophoblastic Neoplasia (GTN)?

    <p>Excessively high β-HCG titer prior to evacuation</p> Signup and view all the answers

    Which histologic category of GTN is characterized by liver or brain metastasis?

    <p>Gestational choriocarcinoma</p> Signup and view all the answers

    What is the most common malignant form of gestational trophoblastic neoplasia?

    <p>Gestational choriocarcinoma</p> Signup and view all the answers

    Which type of gestational trophoblastic neoplasia is characterized by invasion of the myometrium or uterine blood vessels?

    <p>Invasive mole</p> Signup and view all the answers

    Which form of gestational trophoblastic neoplasia tends to develop early blood-borne systemic metastases?

    <p>Gestational choriocarcinoma</p> Signup and view all the answers

    What is the characteristic feature of placental-site trophoblastic tumor (PSTT)?

    <p>Expansive growth mimicking cervical carcinoma</p> Signup and view all the answers

    Which stage of gestational trophoblastic neoplasia involves GTN extending to the lungs, with or without known genital tract involvement?

    <p>Stage III</p> Signup and view all the answers

    At what age does placental-site trophoblastic tumor (PSTT) typically arise?

    <p>&gt;40 years</p> Signup and view all the answers

    Which form of gestational trophoblastic neoplasia has a characteristic serum marker of HPL (human placental lactogen)?

    <p>Placental site trophoblastic disease</p> Signup and view all the answers

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