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Genetic and environmental manipulation of ageing

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9 Questions

How much was the lifespan increase associated with the Age-1 mutation?

50%

What does Age-1 gene encode?

PI3K

What do Daf mutations in the IGF-1 pathway do?

Affect Dauer formation and longevity

What single gene mutation causes Werner syndrome?

WRN

Do dwarf mice with low levels of IGF-1 live shorter lives?

False

What does dietary restriction NOT do?

Increase metabolic activity

What does rapamycin inhibit?

TOR

How much is the increase in lifespan associated with rapamycin?

10-15%

Do mice over expressing GH live longer lives?

False

Test your knowledge about genetics and aging with questions about mutations, gene encoding, and the impact on lifespan. Explore topics like Age-1 mutation, Daf mutations, Werner syndrome, and the effects of dietary restriction.

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