Podcast
Questions and Answers
What condition is caused by a deficiency of Vitamin C?
What condition is caused by a deficiency of Vitamin C?
- Rickets
- Scurvy (correct)
- Osteomalacia
- Gingivitis
Which type of skin cancer is known to be the slowest growing?
Which type of skin cancer is known to be the slowest growing?
- Melanoma
- Basal Cell Carcinoma (correct)
- Squamous Cell Carcinoma
- Keratoacanthoma
Which vitamin is primarily responsible for calcium absorption in the digestive tract?
Which vitamin is primarily responsible for calcium absorption in the digestive tract?
- Vitamin C
- Vitamin D (correct)
- Vitamin A
- Vitamin K
Where is the most common site for Squamous Cell Carcinoma (SCC) in the oral cavity?
Where is the most common site for Squamous Cell Carcinoma (SCC) in the oral cavity?
What deficiency condition results from a lack of Vitamin D in children?
What deficiency condition results from a lack of Vitamin D in children?
Which of the following is a common result of scurvy?
Which of the following is a common result of scurvy?
Basal Cell Carcinoma is most commonly found in which area of the body?
Basal Cell Carcinoma is most commonly found in which area of the body?
Which condition is characterized by bone softening in adults due to Vitamin D deficiency?
Which condition is characterized by bone softening in adults due to Vitamin D deficiency?
What is the primary activity that occurs in keratinocytes within the Stratum Basale?
What is the primary activity that occurs in keratinocytes within the Stratum Basale?
Which layer of the skin is also referred to as the Malpighian Layer?
Which layer of the skin is also referred to as the Malpighian Layer?
Which disease is characterized by the absence of melanin production despite the presence of melanocytes?
Which disease is characterized by the absence of melanin production despite the presence of melanocytes?
What process do cells in the Stratum Granulosum undergo as they become fully keratinized?
What process do cells in the Stratum Granulosum undergo as they become fully keratinized?
What is the primary role of lysosome enzymes during the apoptosis of skin cells?
What is the primary role of lysosome enzymes during the apoptosis of skin cells?
Which amino acid is necessary for the synthesis of melanin, dopamine, and other hormones?
Which amino acid is necessary for the synthesis of melanin, dopamine, and other hormones?
What happens to the tonofilament production in cells of the Stratum Granulosum?
What happens to the tonofilament production in cells of the Stratum Granulosum?
Which of the following statements about the Stratum Granulosum is incorrect?
Which of the following statements about the Stratum Granulosum is incorrect?
What is the primary function of the thoracic duct?
What is the primary function of the thoracic duct?
Which veins connect to the thoracic duct?
Which veins connect to the thoracic duct?
What is the term for the reabsorption failure that results in fluid accumulation?
What is the term for the reabsorption failure that results in fluid accumulation?
Where does the cisterna chyli drain lymph from?
Where does the cisterna chyli drain lymph from?
What occurs to deoxygenated blood after it returns to the heart?
What occurs to deoxygenated blood after it returns to the heart?
Which areas of the body does the thoracic duct primarily connect?
Which areas of the body does the thoracic duct primarily connect?
What might uncontrolled reabsorption lead to?
What might uncontrolled reabsorption lead to?
What is housed in the interstitium?
What is housed in the interstitium?
What condition is characterized by excessive growth of hair in non-common areas?
What condition is characterized by excessive growth of hair in non-common areas?
Which of the following describes a blister that is larger than 5mm?
Which of the following describes a blister that is larger than 5mm?
Which type of skin condition is commonly associated with allergic reactions?
Which type of skin condition is commonly associated with allergic reactions?
Methemoglobinemia results in which notable physical symptom?
Methemoglobinemia results in which notable physical symptom?
What is the primary function of sebaceous glands?
What is the primary function of sebaceous glands?
Which type of skin elevation is characterized as being less than 10mm in diameter?
Which type of skin elevation is characterized as being less than 10mm in diameter?
HPV types 2 and 4 are primarily associated with which skin condition?
HPV types 2 and 4 are primarily associated with which skin condition?
What is the term for the process of scar formation?
What is the term for the process of scar formation?
Which term refers to the excess growth of hair throughout the entire body?
Which term refers to the excess growth of hair throughout the entire body?
What skin condition is defined as itching, but is not synonymous with urticaria?
What skin condition is defined as itching, but is not synonymous with urticaria?
What is the primary function of Vitamin K in the human body?
What is the primary function of Vitamin K in the human body?
Which compound is initially involved in the synthesis of Vitamin D in the skin?
Which compound is initially involved in the synthesis of Vitamin D in the skin?
Which type of tumor is characterized by the presence of keratin pearls?
Which type of tumor is characterized by the presence of keratin pearls?
What is a characteristic clinical feature of melanoma as described by the ABCDE criteria?
What is a characteristic clinical feature of melanoma as described by the ABCDE criteria?
What is the most serious type of skin cancer mentioned in the content?
What is the most serious type of skin cancer mentioned in the content?
What type of sweat glands produces the more viscous and odoriferous sweat?
What type of sweat glands produces the more viscous and odoriferous sweat?
What condition is associated with Vitamin D or calcium deficiency before the closure of the epiphyseal plate?
What condition is associated with Vitamin D or calcium deficiency before the closure of the epiphyseal plate?
In which part of the body are eccrine sweat glands primarily found?
In which part of the body are eccrine sweat glands primarily found?
What is the role of Rhogam or Rho(D) Immune Globulin during pregnancy?
What is the role of Rhogam or Rho(D) Immune Globulin during pregnancy?
Which vitamin is also referred to as ergocalciferol?
Which vitamin is also referred to as ergocalciferol?
What genetic trait influences the baby’s blood type when the mother has a negative Rh factor?
What genetic trait influences the baby’s blood type when the mother has a negative Rh factor?
What is the likely outcome if a second baby is conceived with an Rh-negative mother and an Rh-positive father?
What is the likely outcome if a second baby is conceived with an Rh-negative mother and an Rh-positive father?
What defines a benign mole compared to melanoma?
What defines a benign mole compared to melanoma?
What is the consequence of metaplasia in the context of vitamin D deficiency?
What is the consequence of metaplasia in the context of vitamin D deficiency?
What is the primary function of lymphatic vessels?
What is the primary function of lymphatic vessels?
Which cells are specifically responsible for producing keratin in the epidermis?
Which cells are specifically responsible for producing keratin in the epidermis?
What is the role of macrophages in the lymphatic system?
What is the role of macrophages in the lymphatic system?
Hydrostatic pressure in the capillaries primarily serves to:
Hydrostatic pressure in the capillaries primarily serves to:
Which type of melanin produces a brown to black pigment?
Which type of melanin produces a brown to black pigment?
What type of epithelium characterizes the epidermis?
What type of epithelium characterizes the epidermis?
Where in the spleen are white blood cells primarily found?
Where in the spleen are white blood cells primarily found?
Which fluid is filtered by the lymphatic system before returning to the veins?
Which fluid is filtered by the lymphatic system before returning to the veins?
What purpose do lymph nodes serve in the lymphatic system?
What purpose do lymph nodes serve in the lymphatic system?
What happens to the nucleus of melanocytes in response to UV rays?
What happens to the nucleus of melanocytes in response to UV rays?
What role do Langerhans Cells play in the epidermis?
What role do Langerhans Cells play in the epidermis?
What is the primary goal of the lymphatic system?
What is the primary goal of the lymphatic system?
What are the two main components of the integumentary system?
What are the two main components of the integumentary system?
Which pressure pulls fluid into the capillaries from the interstitium?
Which pressure pulls fluid into the capillaries from the interstitium?
Flashcards
Thoracic Duct
Thoracic Duct
The largest lymphatic duct in the body, responsible for collecting lymph from three-quarters of the body.
Arterial End of Lymphatics
Arterial End of Lymphatics
The end of the lymphatic system where fluids and nutrients are released from the bloodstream to cells in the interstitial space.
Interstitial Space
Interstitial Space
The space between cells where fluid and nutrients are exchanged.
Venous End of Lymphatics
Venous End of Lymphatics
The end of the lymphatic system where excess fluids and waste products are reabsorbed into the bloodstream.
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Reabsorption
Reabsorption
The process of fluids and nutrients being reabsorbed from the interstitial space back into the bloodstream.
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Edema
Edema
An accumulation of fluid in the interstitial space, often caused by impaired lymphatic drainage.
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Cisterna Chyli
Cisterna Chyli
A dilated sac at the lower end of the thoracic duct, which collects lymph from the intestines and lumbar area.
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Lymph Duct Drainage
Lymph Duct Drainage
The lymphatic ducts drain into two specific veins, the internal jugular vein and the subclavian vein, returning lymph to the bloodstream.
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Stratum Corneum
Stratum Corneum
The outer most layer of the epidermis, primarily composed of dead, keratinized cells (corneocytes). It serves as a water-resistant barrier and protects the skin from the environment.
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Stratum Granulosum
Stratum Granulosum
The layer of the epidermis where cells undergo apoptosis (programmed cell death) and begin to flatten. This is also where keratinization (formation of keratin) starts.
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Stratum Basale
Stratum Basale
The deepest layer of the epidermis, responsible for producing new skin cells. It contains actively dividing cells (mitotic activity) and melanocytes.
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Dendritic Cells
Dendritic Cells
A type of cell found primarily in the stratum spinosum, responsible for immune function in the skin. They are also known as Langerhans cells.
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Albinism
Albinism
A genetic condition characterized by the absence of melanin, resulting in pale skin, hair, and eyes.
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Vitiligo
Vitiligo
A skin condition characterized by the loss of melanin in patches, resulting in lighter areas on the skin.
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Keratinization
Keratinization
The process by which cells in the epidermis die and become filled with keratin, forming a tough, protective outer layer (stratum corneum).
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Melanocytes
Melanocytes
The specialized cells in the stratum basale that produce melanin, a pigment responsible for skin color.
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Red Blood Cell Recycling
Red Blood Cell Recycling
The process of recycling red blood cells and breaking them down into their components. This happens primarily in the spleen.
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Lymph
Lymph
The fluid found in the lymphatic vessels, responsible for carrying immune cells and other substances back to the circulatory system.
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Lymph Nodes
Lymph Nodes
Lymphatic structures responsible for filtering lymph, containing lymphocytes for immunity.
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Lymphocytes
Lymphocytes
Functional immune cells produced in the lymph nodes, playing a role in adaptive immunity.
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B Cells
B Cells
Specialized white blood cells that mature into plasma cells, responsible for producing antibodies.
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Plasma Cells
Plasma Cells
White blood cells that develop from B cells and produce antibodies to neutralize pathogens
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Hydrostatic Pressure
Hydrostatic Pressure
The pressure generated by the fluid inside a capillary, pushing fluids outward.
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Oncotic Pressure
Oncotic Pressure
The pressure exerted by proteins in the blood, drawing fluid inward.
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Interstitial Oncotic Pressure
Interstitial Oncotic Pressure
Pressure exerted by proteins in the interstitial fluid, pulling fluid outward from capillaries.
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Blood Oncotic Pressure
Blood Oncotic Pressure
Pressure exerted by proteins in the blood, pulling fluid into the capillaries.
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Integumentary System
Integumentary System
Includes the skin and its associated structures.
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Epidermis
Epidermis
The outermost layer of the skin, composed of stratified squamous epithelium.
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Keratinocytes
Keratinocytes
The most abundant cells in the epidermis. They produce keratin, a protein responsible for the skin's toughness.
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Langerhans Cells
Langerhans Cells
A type of macrophage (immune cell) found in the epidermis, responsible for immune surveillance.
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Vitamin C (Ascorbic Acid)
Vitamin C (Ascorbic Acid)
Vitamin C, also known as ascorbic acid, is crucial for wound healing, maintaining healthy tissues, and boosting immune function.
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Scurvy
Scurvy
Scurvy is a deficiency of Vitamin C, causing symptoms like fatigue, joint pain, bleeding gums, and impaired wound healing.
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Scorbutic Gingivitis
Scorbutic Gingivitis
Scorbutic gingivitis is a type of inflammation of the gums caused by Vitamin C deficiency (scurvy).
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Basal Cell Carcinoma (BCC)
Basal Cell Carcinoma (BCC)
Basal cell carcinoma (BCC) is a common type of skin cancer originating from the basal cells of the epidermis. It's usually slow-growing and often found on the midface.
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Vitamin D (Calciferol, aka Sunshine vitamin)
Vitamin D (Calciferol, aka Sunshine vitamin)
Vitamin D, also known as calciferol and the sunshine vitamin, is crucial for calcium absorption, bone health, and immune function.
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Rickets
Rickets
Rickets is a disease that affects children, characterized by bone softening and deformities due to vitamin D deficiency and inadequate calcium absorption.
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Osteomalacia
Osteomalacia
Osteomalacia is a condition in adults similar to rickets, where bones soften and weaken due to vitamin D deficiency and calcium loss.
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Squamous Cell Carcinoma (SCC)
Squamous Cell Carcinoma (SCC)
Squamous cell carcinoma (SCC) is a common skin cancer arising from the squamous epithelial cells, often found on the lips or skin.
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Vitamin E (Tocopherol)
Vitamin E (Tocopherol)
A vitamin that functions as an antioxidant, protecting the body from free radical damage. It also boosts the immune system.
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Vitamin K
Vitamin K
A vitamin essential for blood clotting. It is produced by bacteria in the small intestine.
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Melanoma
Melanoma
A type of skin cancer that arises from melanocytes. It is the deadliest form of skin cancer due to its high metastatic rate.
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7-dehydrocholesterol
7-dehydrocholesterol
A precursor to Vitamin D3, found in our skin. It is activated by UVB rays from the sun.
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Calcitriol (1,25-dihydroxycholecalciferol)
Calcitriol (1,25-dihydroxycholecalciferol)
The active form of Vitamin D, produced in the kidney. It plays a crucial role in calcium metabolism and bone health.
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Calcidiol
Calcidiol
The inactive form of Vitamin D, produced in the liver. It is converted into the active form, calcitriol, in the kidney.
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Eccrine Sweat Glands
Eccrine Sweat Glands
Glands found throughout the body that produce sweat, helping to regulate body temperature.
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Apocrine Sweat Glands
Apocrine Sweat Glands
Glands concentrated in the axilla, areola, and perianal regions that produce a protein-rich sweat, responsible for body odor.
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Ceruminous Glands
Ceruminous Glands
Glands located in the ear canal that secrete cerumen, commonly known as earwax.
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Photosensitivity
Photosensitivity
The term used to describe excessive sensitivity to light, particularly UV rays. It can be a side effect of certain medications.
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Erythroblastosis Fetalis
Erythroblastosis Fetalis
A condition caused by Rh incompatibility between a mother and her baby, leading to the breakdown of red blood cells in the baby's blood, resulting in a bluish discoloration of the skin.
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Blue Baby Syndrome
Blue Baby Syndrome
A condition caused by Rh incompatibility between a mother and her baby, leading to the breakdown of red blood cells in the baby's blood, resulting in a bluish discoloration of the skin.
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Vitamin D2 (Ergocalciferol)
Vitamin D2 (Ergocalciferol)
A type of Vitamin D found in plant diets, also known as Ergocalciferol.
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Vitamin D3 (Cholecalciferol)
Vitamin D3 (Cholecalciferol)
A type of Vitamin D synthesized in the skin upon exposure to UVB rays, also known as Cholecalciferol.
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Methemoglobinemia
Methemoglobinemia
A blood disorder where there is too much methemoglobin in the blood. This results in the blood not carrying oxygen molecules, causing a bluish discoloration of the skin.
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Arrector pili muscles
Arrector pili muscles
The smooth muscle responsible for creating 'goosebumps' on the skin.
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Alopecia
Alopecia
Partial or complete loss of hair. It can often be treated with the medication minoxidil.
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Hirsutism
Hirsutism
Excessive hair growth localized to specific areas.
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Hypertrichosis
Hypertrichosis
Excess hair growth all over the body. It is often linked to a Y-linked inheritance pattern.
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Sebaceous Glands
Sebaceous Glands
Glands responsible for secreting sebum, an oily substance that prevents water from evaporating from the skin.
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Cicatrix
Cicatrix
A type of scar, often referred to as CICA
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Ephelis or Ephelides
Ephelis or Ephelides
Another name for freckles, which are caused by excessive melanin.
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Rule of 9
Rule of 9
A method to assess the percentage of burn body part. Used to estimate the severity of burns based on the percentage of the body affected.
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Blister
Blister
Fluid-filled lesions.
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Bula/Bullae
Bula/Bullae
A large blister with fluid, 5mm or larger.
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Vesicle
Vesicle
A small blister with fluid, less than 5mm.
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Cyst
Cyst
A fluid-filled, semi-fluid filled, or air-filled sac with a developed epithelial wall. The presence of this epithelial wall is what defines a cyst.
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Papule
Papule
An elevation of the skin less than 10 mm in diameter.
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Nodule
Nodule
An elevation of the skin larger than 10 mm in diameter.
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Hives
Hives
Medically referred to as 'urticaria'. This is characterized by reddened, elevated, itchy patches of skin, often caused by allergic reactions.
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Pruritus
Pruritus
Itching, medically known as Pruritus
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Common Wart (Verruca Vulgaris)
Common Wart (Verruca Vulgaris)
Common warts, often caused by HPV (Human Papillomavirus). The most common types are HPV2 and HPV4.
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HPV16 and HPV18
HPV16 and HPV18
High-risk HPV strains like HPV16 and HPV18 can lead to cervical cancer, but they are NOT related to common wart formation.
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Lymphatic System
- Lymphatic system absorbs fluids not absorbed by capillaries
- This is to prevent fluid buildup, also known as edema
- It filters fluids in the circulatory system
- Lymph nodes clean and filter fluids and return them to veins
- Lymph nodes act as checkpoints in the lymphatic system
Lymphatic Organs
- Bone marrow and thymus are primary lymphatic organs
- Lymph nodes, spleen, and tonsils are secondary organs
- These organs produce lymphocytes (a type of white blood cell)
Lymphatic Circulation
- Begins with the heart
- Blood is pumped through arteries, arterioles, and capillaries
- Fluids and nutrients move from capillaries into cells
- Fluids return to capillaries, known as reabsorption
- If reabsorption doesn't occur properly, edema will result
Lymphatic Ducts
- Lymphatic ducts are the largest lymphatic vessels
- They carry lymph (filtered fluid) to veins
- There are two main ducts: left (thoracic) and right
- Left lymphatic duct is larger and drains most of the body
Spleen
- Red pulp of the spleen contains red blood cells and macrophages
- White pulp of the spleen contains white blood cells (B and T lymphocytes)
- Which specifically turn into plasma cells
Capillary Dynamics
- Interstitial fluid has oncotic pressure, and blood has its own oncotic pressure
- Hydrostatic pressure pushes fluid into capillaries
- Hydrostatic pressure of interstitium and hydrostatic pressure of blood move fluids in opposite directions
- Capillary movement is controlled by pressures like blood hydrostatic pressure, blood oncotic pressure, interstitial hydrostatic pressure, and interstitial oncotic pressure
Integumentary System
- Largest system of the body, mostly the skin
- Consists of the epidermis and dermis
- Epidermis is the outer layer (keratinized stratified squamous epithelium)
- Contains 4 cell types: keratinocytes, melanocytes, Langerhans cells, and Merkel cells
Epidermis Layers
- Stratum basale is the deepest layer, responsible for keratin production and mitotic activity
- Stratum spinosum is the thickest layer
- Stratum granulosum, lucidum, and corneum have no mitotic activity
Layers
- Stratum Corneum: outermost layer, composed of dead keratinocytes
- Stratum Lucidum: clear cell layer, present in thick skin (palms, soles)
- Stratum Granulosum: keratinocytes begin to die
- Stratum Spinosum: numerous cells, abundant keratin filaments
- Stratum Basale: deepest layer, containing stem cells and melanocytes
Medical Terms
- Cyanosis: bluish discoloration due to inadequate oxygen
- Blue Baby Syndrome: birth defect characterized by bluish skin
- Arrector pili muscles: cause goosebumps
- Alopecia: hair loss
- Hair Hypertrichosis or hirsutism: excess hair growth
- Sweat glands, ceruminous glands, and osteomalacia and rickets are related to calcium/vitamin D deficiencies
Skin Cancer
- Basal cell carcinoma and squamous cell carcinoma are common skin cancers
- Melanoma is the deadliest skin cancer, with high metastatic rate
Vitamins
- Vitamin deficiencies can cause various health problems, including impaired vision, beriberi, and pellagra
- Importance of vitamins for RBC production, bone health, and immunity
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