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BIOCHEM L3C | Water Soluble Vitamins
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BIOCHEM L3C | Water Soluble Vitamins

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Questions and Answers

Which of the following is true about water-soluble vitamins?

  • Water-soluble vitamins are stored in the liver
  • Excess water-soluble vitamins are stored in the fat cells
  • The body has no storage capacity for most water-soluble vitamins, except for vitamin B9 & B12 (correct)
  • The body stores all water-soluble vitamins for later use
  • What is the role of vitamin B1 in the body?

  • It is primarily involved in iron metabolism
  • It is responsible for calcium absorption in the intestines
  • It acts as an antioxidant in the body
  • It serves as a coenzyme in carbohydrate, fat, and protein metabolism reactions (correct)
  • What is the active form of vitamin B1?

  • Niacinamide
  • Cobalamin
  • Thiamine pyrophosphate (TPP) (correct)
  • Riboflavin
  • What are the symptoms of vitamin B1 deficiency?

    <p>Loss of appetite, constipation, and nausea</p> Signup and view all the answers

    How quickly can thiamine depletion, leading to vitamin B1 deficiency, occur?

    <p>Approximately 14 days</p> Signup and view all the answers

    What happens to any excess water-soluble vitamins in the body?

    <p>They are excreted in the urine</p> Signup and view all the answers

    Which vitamin functions as a cofactor for dehydrogenase enzyme reactions including pyruvate dehydrogenase and α-ketoglutarate dehydrogenase?

    <p>Vitamin B1</p> Signup and view all the answers

    What is the primary deficiency symptom associated with impaired glucose breakdown and ATP depletion?

    <p>Dilated cardiomyopathy</p> Signup and view all the answers

    Which vitamin deficiency leads to glossitis and symptoms of pellagra such as diarrhea, dementia, and dermatitis?

    <p>Vitamin B3</p> Signup and view all the answers

    Which vitamin acts as a cofactor for the synthesis of cystathionine, heme, niacin, histamine, and neurotransmitters such as serotonin and dopamine?

    <p>Vitamin B6</p> Signup and view all the answers

    Which vitamin deficiency can cause convulsions, hyperirritability, and peripheral neuropathy?

    <p>Vitamin B12</p> Signup and view all the answers

    What is the main function of Vitamin B9 (Folate)?

    <p>Coenzyme for 1-carbon transfer/methylation reactions</p> Signup and view all the answers

    Which vitamin is responsible for the conversion of dopamine into norepinephrine?

    <p>Vitamin B6</p> Signup and view all the answers

    Which vitamin deficiency can lead to scurvy and collagen synthesis defects?

    <p>Vitamin C</p> Signup and view all the answers

    Which vitamin is derived from tryptophan and acts as a component of NAD+ and NADP+ used in redox reactions?

    <p>Vitamin B3</p> Signup and view all the answers

    What is the primary symptom associated with Vitamin B5 (Pantothenic acid) deficiency?

    <p>Alopecia</p> Signup and view all the answers

    What is the primary symptom associated with Vitamin B6 (Pyridoxine) deficiency?

    <p>Convulsions</p> Signup and view all the answers

    Which combination of symptoms is known as Wernicke-Korsakoff psychosis?

    <p>Mental confusion, ataxia, and loss of eye coordination</p> Signup and view all the answers

    Which vitamin deficiency results in angular stomatitis, glossitis, and scaly dermatitis?

    <p>Vitamin B2</p> Signup and view all the answers

    Which vitamin is required for synthesis of NAD+ and NADP+ related to energy expenditure?

    <p>Vitamin B3</p> Signup and view all the answers

    Which vitamin participates in carbohydrate and lipid metabolism and is particularly important for amino acid metabolism?

    <p>Vitamin B6</p> Signup and view all the answers

    What serves as a coenzyme in multienzyme complexes involved in carboxylation reactions in lipogenesis and gluconeogenesis?

    <p>Vitamin B7</p> Signup and view all the answers

    Which vitamin deficiency can cause depression, hallucinations, muscle pain, hair loss, and dermatitis?

    <p>Vitamin B7</p> Signup and view all the answers

    Which vitamin is required for the synthesis of the neurotransmitters like serotonin and noradrenaline?

    <p>Vitamin B6</p> Signup and view all the answers

    Which vitamin is necessary for the synthesis of purines and pyrimidine thymine?

    <p>Folic acid</p> Signup and view all the answers

    What is the vitamin deficiency characterized by megaloblastic anemia, fatigue, constipation, and neurologic symptoms?

    <p>Vitamin B12 deficiency</p> Signup and view all the answers

    In which form is Vitamin B12 absent from all plants but concentrated in animal livers, fish, and dairy products?

    <p>All of the above</p> Signup and view all the answers

    What vitamin deficiency can lead to capillary fragility, muscle weakness, soft, swollen, bleeding gums, and anemia?

    <p>Vitamin C deficiency</p> Signup and view all the answers

    Which vitamin is responsible for improving the absorption of nonheme iron and participating in bone mineral metabolism?

    <p>Vitamin C</p> Signup and view all the answers

    What is the primary function of Vitamin C?

    <p>Maintaining metal cofactors in lower valence states</p> Signup and view all the answers

    What vitamin is synthesized solely by bacteria and is absent from all plants?

    <p>Vitamin B12</p> Signup and view all the answers

    Which vitamin participates in nucleic acid synthesis and the production of erythrocytes?

    <p>(Cobalamin) Vitamin B12</p> Signup and view all the answers

    In which deficiency can individuals experience reduced immunocompetence and poor wound healing?

    <p>(Ascorbic acid) Vitamin C deficiency</p> Signup and view all the answers

    What is the complex ring structure of Vitamin B12 similar to?

    <p>Porphyrin of heme</p> Signup and view all the answers

    What is the essential function of Vitamin C in collagen synthesis?

    <p>Hydroxylation of proline &amp; lysine</p> Signup and view all the answers

    What are the sources of Folic acid (Vitamin B9)?

    <p>Liver, yeast, green leafy vegetables (spinach), citrus fruits</p> Signup and view all the answers

    Study Notes

    Water-Soluble Vitamins

    • Water-soluble vitamins are not stored in the body, and excess amounts are excreted in the urine.
    • Vitamin B1 (Thiamine) plays a crucial role in the body as a cofactor for dehydrogenase enzyme reactions, including pyruvate dehydrogenase and α-ketoglutarate dehydrogenase.
    • The active form of Vitamin B1 is Thiamine pyrophosphate (TPP).

    Vitamin B1 Deficiency

    • Symptoms of Vitamin B1 deficiency include impaired glucose breakdown, ATP depletion, and symptoms of Beri-Beri, such as muscle weakness, fatigue, and nerve damage.
    • Thiamine depletion can occur rapidly, leading to Vitamin B1 deficiency.

    Vitamin B3 (Niacin)

    • Vitamin B3 deficiency leads to Pellagra, characterized by symptoms such as diarrhea, dementia, and dermatitis.
    • Vitamin B3 is synthesized from tryptophan and acts as a component of NAD+ and NADP+ used in redox reactions.

    Vitamin B5 (Pantothenic acid)

    • The primary symptom associated with Vitamin B5 deficiency is fatigue.

    Vitamin B6 (Pyridoxine)

    • The primary symptom associated with Vitamin B6 deficiency is neuropathy.

    Vitamin B9 (Folate)

    • The main function of Vitamin B9 is to participate in nucleic acid synthesis and the production of erythrocytes.
    • Sources of Folic acid include leafy green vegetables, legumes, and fortified cereals.

    Vitamin B12

    • Vitamin B12 is required for the synthesis of the neurotransmitters like serotonin and noradrenaline.
    • Vitamin B12 deficiency is characterized by megaloblastic anemia, fatigue, constipation, and neurologic symptoms.
    • Vitamin B12 is absent from all plants but concentrated in animal livers, fish, and dairy products.

    Vitamin C

    • The primary function of Vitamin C is to improve the absorption of nonheme iron and participate in bone mineral metabolism.
    • Vitamin C deficiency can lead to scurvy, capillary fragility, muscle weakness, soft, swollen, bleeding gums, and anemia.
    • Vitamin C is essential for collagen synthesis, and its deficiency can lead to poor wound healing.

    Other Vitamins

    • Vitamin B2 (Riboflavin) is required for the synthesis of cystathionine, heme, and neurotransmitters such as serotonin and dopamine.
    • Vitamin B6 (Pyridoxine) is responsible for the conversion of dopamine into norepinephrine.
    • Biotin serves as a coenzyme in multienzyme complexes involved in carboxylation reactions in lipogenesis and gluconeogenesis.

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