Vitamin A Toxicity Quiz
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Questions and Answers

Which of the following is a symptom of vitamin A deficiency?

  • Night blindness
  • Increased susceptibility to respiratory infections
  • Excessive mucin production
  • Xerophthalmia (correct)
  • Dry skin and hair

    • What is the recommended dietary allowance (RDA) of vitamin A for adult women?

  • 9,900 IU/day
  • 5,000 IU/day
  • 2,300 IU/day (correct)
  • 3,000 IU/day
  • 1,000 IU/day

    • How does retinoic acid influence gene expression?

  • By thinning the epithelial tissue
  • By inhibiting keratinization
  • By combining with nuclear receptors (correct)
  • By increasing mucin production
  • By promoting cell growth

    • Which vitamin A derivative is used for the treatment of severe cystic acne?

    <p>Isotretinoin (Accutane)</p> Signup and view all the answers

    What is the upper limit (UL) of vitamin A intake for adults?

    <p>10,000 IU/day</p> Signup and view all the answers

    Which of the following is a symptom of vitamin A toxicity?

    <p>Thickening of the mucin layer in the skin</p> Signup and view all the answers

    What is the primary cause of reported cases of vitamin A toxicity?

    <p>Inappropriate use of vitamin supplements (retinol)</p> Signup and view all the answers

    Which vitamin A derivative is contraindicated for use by pregnant women due to teratogenicity?

    <p>Isotretinoin (Accutane)</p> Signup and view all the answers

    What is the recommended dietary allowance (RDA) of vitamin A for adult men?

    <p>$3,000 IU/day$</p> Signup and view all the answers

    How does retinoic acid influence gene expression?

    <p>By combining with nuclear receptors to influence the growth, differentiation, and function of target cells</p> Signup and view all the answers

    What is the primary cause of reported cases of vitamin A toxicity?

    <p>Ingestion of vitamin supplements (retinol)</p> Signup and view all the answers

    What is the mechanism of action (MOA) of retinoic acid in influencing gene expression?

    <p>Combining with nuclear receptors to influence gene expression</p> Signup and view all the answers

    Which symptom is NOT associated with vitamin A deficiency?

    <p>Increased susceptibility to respiratory infections</p> Signup and view all the answers

    Which vitamin A derivative is used for the treatment of acute promyelocytic leukemia (APL)?

    <p>All-trans-retinoic acid (ATRA)</p> Signup and view all the answers

    What is the upper limit (UL) of vitamin A intake for adults?

    <p>(9,900 IU/day)</p> Signup and view all the answers

    Which of the following is a potential consequence of excessive concentrations of retinoids where goblet cells are present?

    <p>Thickening of the mucin layer and extreme thinning of the epithelial tissue</p> Signup and view all the answers

    What is the primary concern associated with the use of Isotretinoin (Accutane) by pregnant women?

    <p>Teratogenicity</p> Signup and view all the answers

    Which condition results from vitamin A deficiency and leads to permanent blindness?

    <p>Xerophthalmia</p> Signup and view all the answers

    What is the recommended dietary allowance (RDA) of vitamin A for adult men?

    <p>$3,000 IU/day$</p> Signup and view all the answers

    What is the upper limit (UL) of vitamin A intake for adults?

    <p>$9,900 IU/day$</p> Signup and view all the answers

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