Vitamin A Toxicity Quiz
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Questions and Answers

Which of the following is a symptom of vitamin A deficiency?

  • Night blindness
  • Increased susceptibility to respiratory infections
  • Excessive mucin production
  • Xerophthalmia (correct)
  • Dry skin and hair

What is the recommended dietary allowance (RDA) of vitamin A for adult women?

  • 9,900 IU/day
  • 5,000 IU/day
  • 2,300 IU/day (correct)
  • 3,000 IU/day
  • 1,000 IU/day

How does retinoic acid influence gene expression?

  • By thinning the epithelial tissue
  • By inhibiting keratinization
  • By combining with nuclear receptors (correct)
  • By increasing mucin production
  • By promoting cell growth

Which vitamin A derivative is used for the treatment of severe cystic acne?

<p>Isotretinoin (Accutane) (B)</p> Signup and view all the answers

What is the upper limit (UL) of vitamin A intake for adults?

<p>10,000 IU/day (C)</p> Signup and view all the answers

Which of the following is a symptom of vitamin A toxicity?

<p>Thickening of the mucin layer in the skin (E)</p> Signup and view all the answers

What is the primary cause of reported cases of vitamin A toxicity?

<p>Inappropriate use of vitamin supplements (retinol) (C)</p> Signup and view all the answers

Which vitamin A derivative is contraindicated for use by pregnant women due to teratogenicity?

<p>Isotretinoin (Accutane) (D)</p> Signup and view all the answers

What is the recommended dietary allowance (RDA) of vitamin A for adult men?

<p>$3,000 IU/day$ (C)</p> Signup and view all the answers

How does retinoic acid influence gene expression?

<p>By combining with nuclear receptors to influence the growth, differentiation, and function of target cells (B)</p> Signup and view all the answers

What is the primary cause of reported cases of vitamin A toxicity?

<p>Ingestion of vitamin supplements (retinol) (D)</p> Signup and view all the answers

What is the mechanism of action (MOA) of retinoic acid in influencing gene expression?

<p>Combining with nuclear receptors to influence gene expression (D)</p> Signup and view all the answers

Which symptom is NOT associated with vitamin A deficiency?

<p>Increased susceptibility to respiratory infections (B)</p> Signup and view all the answers

Which vitamin A derivative is used for the treatment of acute promyelocytic leukemia (APL)?

<p>All-trans-retinoic acid (ATRA) (C)</p> Signup and view all the answers

What is the upper limit (UL) of vitamin A intake for adults?

<p>(9,900 IU/day) (C)</p> Signup and view all the answers

Which of the following is a potential consequence of excessive concentrations of retinoids where goblet cells are present?

<p>Thickening of the mucin layer and extreme thinning of the epithelial tissue (D)</p> Signup and view all the answers

What is the primary concern associated with the use of Isotretinoin (Accutane) by pregnant women?

<p>Teratogenicity (B)</p> Signup and view all the answers

Which condition results from vitamin A deficiency and leads to permanent blindness?

<p>Xerophthalmia (C)</p> Signup and view all the answers

What is the recommended dietary allowance (RDA) of vitamin A for adult men?

<p>$3,000 IU/day$ (B)</p> Signup and view all the answers

What is the upper limit (UL) of vitamin A intake for adults?

<p>$9,900 IU/day$ (A)</p> Signup and view all the answers

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