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Questions and Answers
What effect does light have on photoreceptors?
What effect does light have on photoreceptors?
What is the role of less released glutamate in bipolar cells?
What is the role of less released glutamate in bipolar cells?
Which structure in the visual system is responsible for crossing visual information from the contralateral side?
Which structure in the visual system is responsible for crossing visual information from the contralateral side?
What happens if enough EPSP is generated in a ganglion cell?
What happens if enough EPSP is generated in a ganglion cell?
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In the visual pathway, where does visual information finally reach?
In the visual pathway, where does visual information finally reach?
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What is the primary function of the lateral rectus muscle?
What is the primary function of the lateral rectus muscle?
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Which structure of the eye acts as a protective, transparent covering?
Which structure of the eye acts as a protective, transparent covering?
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What triggers the pupils to constrict during close vision?
What triggers the pupils to constrict during close vision?
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What is the primary role of the retinal pigmented layer?
What is the primary role of the retinal pigmented layer?
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During which state do pupils dilate as a response to emotional changes?
During which state do pupils dilate as a response to emotional changes?
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Which layer of the eye contains the blood vessels and is darkly pigmented?
Which layer of the eye contains the blood vessels and is darkly pigmented?
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What is the main function of the lacrimal glands?
What is the main function of the lacrimal glands?
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Which part of the eye is responsible for light sensing?
Which part of the eye is responsible for light sensing?
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What is the primary function of rods in the visual system?
What is the primary function of rods in the visual system?
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Which type of cell in the retina primarily responds to bright light and produces color vision?
Which type of cell in the retina primarily responds to bright light and produces color vision?
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What neurotransmitter is released by horizontal cells upon depolarization?
What neurotransmitter is released by horizontal cells upon depolarization?
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What occurs to retinal in the rods when they absorb light?
What occurs to retinal in the rods when they absorb light?
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What is the main purpose of the amacrine cells in the retina?
What is the main purpose of the amacrine cells in the retina?
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Which photopigment is associated with rods for vision in low light?
Which photopigment is associated with rods for vision in low light?
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What distinguishes color blindness in terms of the types of cones affected?
What distinguishes color blindness in terms of the types of cones affected?
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What role do bipolar cells play during light and dark conditions?
What role do bipolar cells play during light and dark conditions?
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What is the metabolic role of the inner segment of photoreceptors?
What is the metabolic role of the inner segment of photoreceptors?
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How do the three types of cones contribute to color vision?
How do the three types of cones contribute to color vision?
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Which of the following accurately describes the role of taste receptors?
Which of the following accurately describes the role of taste receptors?
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What is the primary function of the tympanic membrane?
What is the primary function of the tympanic membrane?
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Which statement is true about the process of dynamic equilibrium?
Which statement is true about the process of dynamic equilibrium?
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Which of the following statements about smell receptors is accurate?
Which of the following statements about smell receptors is accurate?
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What distinguishes sensorineural deafness from conduction deafness?
What distinguishes sensorineural deafness from conduction deafness?
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Which of the following structures is part of the inner ear?
Which of the following structures is part of the inner ear?
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How do otoliths contribute to static equilibrium?
How do otoliths contribute to static equilibrium?
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Which nerve is primarily involved in transmitting taste impulses to the brain?
Which nerve is primarily involved in transmitting taste impulses to the brain?
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The organ responsible for detecting sound waves in the cochlea is known as:
The organ responsible for detecting sound waves in the cochlea is known as:
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What role does the pharyngotympanic tube serve?
What role does the pharyngotympanic tube serve?
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Which of the following best explains the mechanics of hearing?
Which of the following best explains the mechanics of hearing?
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Which component of balance and equilibrium primarily responds to gravity?
Which component of balance and equilibrium primarily responds to gravity?
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What is the function of the semicircular canals?
What is the function of the semicircular canals?
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How does motion sickness occur according to the equilibrium system?
How does motion sickness occur according to the equilibrium system?
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Which of the following tastes is NOT considered one of the five basic tastes?
Which of the following tastes is NOT considered one of the five basic tastes?
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Study Notes
Lecture 4: Special Senses
- This lecture covers the special senses, including the visual, chemical (taste and smell), auditory, and vestibular systems. It draws on Sherwood Chapter 5 for detailed information.
Objectives
- The lecture will cover the visual system, including the eye itself and its accessory structures.
- It will look at chemical senses (taste and smell).
- The auditory system will be explored.
- Finally, the vestibular system will be discussed.
Visual System: The Eye
- 70% of all sensory receptors are located in the eye.
- The eye is largely sheltered by fat and bony orbit.
- Accessory structures include:
- Eyebrows: shade the eye and prevent perspiration.
- Eyelids: protect the eye, and have glands that secrete oil.
- Eye lashes: initiate reflexive blinking.
- Eye muscles: control eye movement.
Visual System: Extraocular Muscles
- Lateral Rectus Muscle: abducts the eye.
- Medial Rectus Muscle: adducts the eye.
- Superior Rectus Muscle: moves the eye upward.
- Inferior Rectus Muscle: moves the eye downward.
- Superior Oblique Muscle: moves the eye downward.
- Inferior Oblique Muscle: moves the eye upward.
Visual System: Structures of the Eye
- Cornea: transparent, protective covering of the iris and pupil.
- Sclera: protective, white, connective tissue covering.
- Conjunctiva: epithelial layer connecting the sclera to the eyelids.
- Lacrimal glands: secrete aqueous tear film which lubricates the eye.
Visual System: Structures of the Eye
- Iris: the colored part of the eyeball, regulates the amount of light entering the eye.
- Pupil: central opening of the iris. -Pupil constrict in bright light and close vision -Pupils dilate in dim light and during emotional states
- Lens: clear, flexible tissue responsible for focusing.
- Retina: light-sensing tissue at the back of the eye.
- A delicate, two-layered membrane with photoreceptors
Visual System: Retinal Layers
- Pigmented Layer: absorbs stray light rays.
- Neural Layer: processes visual data.
Visual System: Cells of the Retina
- Photoreceptors:
- Rods: numerous (~120 million), used for dim light and peripheral vision, do not detect colour, see grayscale.
- Cones: less numerous (~6 million), detect colour in bright light.
- Ganglion Cells: receive visual information from photoreceptors and send signals to the optic nerve, ON and OFF responses associated with light/dark.
- Bipolar Cells: receive signals from photoreceptors and transmit signals to ganglion cells.
- Horizontal Cells: modulate signaling between photoreceptors and bipolar cells.
- Amacrine Cells: modulate signaling between ganglion and bipolar cells.
Visual System: Cells of the Retina (more detailed)
- Outer Segment: detects light, contains photopigments.
- Inner Segment: metabolic area of the receptor.
- Synaptic Terminal: transmits signals to bipolar cells.
Visual System: Light Sensitive Photopigment
- Photopigments are present in the rods and cones.
- Rhodopsin (rods): absorbs all wavelengths of light.
- Photopsin (cones): three types (red, green, blue) for colour vision.
Visual System: Dark Vision (Rods)
- 11-cis-retinal in the dark.
- All-trans-retinal in the light.
- Light stimulus causes retinal to change shape.
- That starts the conversion of energy (photon) into a nerve impulse
- Conversion of 11-cis-retinal to all-trans-retinal in response to light initiates the process of transduction.
- The conversion of 11-cis-retinal to all-trans-retinal in response to light initiates the process of transduction.
Visual System: Colour Vision (Cones)
- Three types of photoreceptors:
- Photopsin I (red)
- Photopsin II (green)
- Photopsin III (blue)
- Colour vision is the result of combinations of these cone stimulations
- Colour blindness is related to lack of one or more cone types.
Chemical Senses (Taste and Smell):
- Their chemoreceptors respond to chemicals dissolved in solutions.
- Taste – dissolved in Saliva
- Smell – dissolved in nasal fluids
- 5 basic tastes: Sweet, Sour, Salty, Bitter and Umami
- Taste and smell are closely related; smell contributes substantially to taste experience.
Taste Receptors (Gustation)
- Located along edges of small, depressed areas called fissures (on the tongue)
- Stimulated when substance is dissolved in solution
- Taste receptors are often G-protein coupled receptors.
- Taste is sent to the brain via CN VII (facial nerve) and CN IX.
Smell Receptors (Olfaction)
- Located in the olfactory epithelium (upper part of nasal cavity)
- Chemicals detected must be dissolved in solution
- Must "sniff" to bring odors upward.
Hearing:
- The ear (inner, outer, and middle ear) contains hearing and balance receptors.
- The outer and middle ear are involved in hearing only.
- Receptors for hearing and balance respond to different stimuli independently.
The Ear (overall summary of structures):
- Houses hearing and equilibrium
- The three parts of the ear: external (outer), middle and inner ear; and receptors for hearing and balance.
- Hearing and balance receptors respond to separate stimuli.
- They are activated independently
Anatomy of the Ear
- External ear (outer): pinna and external auditory meatus, lined with ceruminous glands that secrete cerumen
- Middle ear (tympanic membrane): sound waves cause vibration that moves the auditory ossicles
- Inner ear (bony labyrinth): vestibule, semicircular canals and cochlea,
- These structures have hair cells -In the inner ear, hair cells are mechanoreceptors.
Internal Ear
- Comprised of bony chambers in the temporal bone that house parts for hearing and balance
-The vestibule and semicircular canals are used for balance
- The cochlea contains hair cells, mechanoreceptors for hearing
The Cochlea (of the Inner Ear)
- Contains the spiral organ of Corti.
- The spiral organ of Corti contains thousands of hair cells.
- These hair cells are receptors for hearing.
Organ of Corti (detailed look at the cochlea)
- Contains hair cells that are the hearing receptors.
- Sound waves, travelling through the ear, causes vibration in fluids of the cochlea.
- These vibrations stimulate hair cells which then transmit signals through the cochlear nerve and onto the auditory cortex.
Sound Transduction:
- Sound waves vibrate the eardrum.
- These vibrations are transmitted across the middle ear and vibrate the oval window (of inner ear).
- Vibrations cause fluid movement in the cochlea.
- This movement causes bending of hairs on inner hair cells located on the basilar membrane which leads to transduction of vibrations into electrical signals to be sent further along.
Auditory Pathway
- The auditory pathway includes the cochlea, vestibulocochlear nerve, medulla, midbrain and the medial geniculate body of the thalamus and the primary auditory cortex.
- Vibrations are transduced and carried to the auditory cortex in the temporal lobe.
Deafness
- Sensorineural deafness: issues with hair cells, cochlear nerve or neurons.
- Could be caused by prolonged drug exposure, loud noise.
- Conduction deafness: sound vibrations cannot reach inner ear due to buildup of earwax or injury to eardrum.
The Vestibular System
- Responds to head movements.
- Equilibrium receptors in the inner ear.
- Static equilibrium - Vestibule (responds to head position relative to gravity)
- Dynamic equilibrium - Semicircular canals (responds to head position/movement relative to body motion)
Anatomy of the Vestibular Apparatus
- Consists of the bony and membranous labyrinths. -Bony labyrinth – filled with perilymph, -Membranous labyrinth - suspended within the perilymph and filled with endolymph.
Static Equilibrium
- Macula: patches of hair cells embedded in otolithic membrane w/ tiny stones (otoliths)
- Otoliths' movement in response to head position pulls on the gel, bending hair cells, sending impulses to the cerebellum.
Dynamic Equilibrium
- Cristae ampullaris: Hair cells in semicircular canals covered by the cupula.
- When the head moves, endolymph lags behind causing the cupula to deflect, stimulating hair cells, sending vestibular nerve impulses to cerebellum.
Balance and Orientation Pathways
- Three input modes: vestibular receptors, visual receptors, and somatic receptors.
- These receptors allow the body to respond reflexively to maintain balance and orientation.
Input and output of the Vestibular Nuclei
- Visual, cutaneous, and proprioceptive inputs are used in coordination
Homeostatic Imbalance: Motion Sickness
- Sensory mismatch between vestibular and visual inputs from movement results in motion sickness
Lecture 4 Pop Quiz Questions
- These are questions for a quiz. The questions are about the different special senses. -Function of middle and inner ear -Process of transmission of impulses to auditory cortex -Difficulties differentiating between conduction and sensorineural deafness -Static and dynamic equilibrium differences -Description of how dynamic equilibrium works -Case study examining vertigo, semicircular canals and how the brain processes conflicting impulses to generate motion sickness
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Explore the intricate details of photoreceptors and their role in the visual system through this quiz. Dive into topics such as the effect of light on photoreceptors, the function of glutamate in bipolar cells, and the crossing of visual information. Test your understanding of the visual pathway and its components.