Visceral vs

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Which of the following drugs inhibits the reuptake of both norepinephrine (NE) and dopamine (DA)?

Ketamine

THC

Bupropion (Zyban) (correct)

Xylazine

Which receptor does THC act as a partial agonist at?

kappa receptor

Alpha-2

CB1R (correct)

nAChR

Which of the following drugs is an NMDA antagonist?

Xylazine

Ketamine and PCP (correct)

Bupropion (Zyban)

THC

Which receptor does nicotine selectively agonize?

nAChR Signup and view all the answers

Which of the following is NOT a characteristic of tolerance?

Build tolerance to hallucinations Signup and view all the answers

Which of the following is a major structure of hallucinogens?

Phenylalkylamines Signup and view all the answers

Which type of pain is characterized by deep, aching, and poorly localized sensations?

Visceral pain Signup and view all the answers

What is the recommended maximum daily intake of acetaminophen to avoid hepatotoxicity?

4 grams Signup and view all the answers

Which of the following is a long-term benefit of quitting smoking?

Decreased lung cancer risk Signup and view all the answers

Which enzyme is induced when actively smoking and can affect drug metabolism?

CYP1A2 Signup and view all the answers

Which vitamin is important to prevent Wernicke-Korsakoff syndrome during alcohol withdrawal treatment?

Thiamine Signup and view all the answers

Which medication used for alcohol dependence can cause diarrhea as a common side effect?

Acamprosate Signup and view all the answers

What is the recommended dosing of Disulfiram (Antabuse) for alcohol dependence?

666mg three times daily Signup and view all the answers

Which medication has a ceiling effect on respiratory depression and for analgesia?

Buprenorphine Signup and view all the answers

Which medication should be used with caution when transferring from a pure agonist to it due to the risk of precipitated withdrawal?

Buprenorphine Signup and view all the answers

Which medication is no longer used due to the risk of accumulation of the active metabolite, normaperedine, which can cause seizures in patients with impaired renal function?

Meperidine Signup and view all the answers

Which class of medications is used in fibromyalgia, and if contraindicated, Duloxetine can be used as an alternative?

TCAs Signup and view all the answers

Which medication class should be avoided in older adults, patients with glaucoma, enlarged prostate, and seizure disorder due to their anticholinergic effects?

Anticholinergic drugs Signup and view all the answers

When converting to another opioid, what adjustment should be made to the dose to account for incomplete tolerance?

Decrease the dose Signup and view all the answers

Which opioid has a long half-life and is lipophilic, making it dangerous at initiation due to the potential accumulation and risk of respiratory depression?

Methadone Signup and view all the answers

What should be used to control breakthrough pain, and at what dose relative to the daily dose?

Immediate-release formulations at 10-15% of daily dose Signup and view all the answers

Which medication class should not be used together with benzodiazepines due to the risk of respiratory depression?

Opioids Signup and view all the answers

During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.

Alcohol concentration in the brain is higher than alcohol concentration in the blood during absorption. Signup and view all the answers

Peak brain alcohol concentration is achieved at 15 minutes. Peak blood alcohol concentration is achieved at 75 minutes.

Peak brain alcohol concentration is achieved at 75 minutes. Peak blood alcohol concentration is achieved at 15 minutes. Signup and view all the answers

Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) have considerable polymorphisms.

Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) have polymorphisms. Signup and view all the answers

The variant ADH1B*2 increases vmax, resulting in faster conversion of ethanol to acetaldehyde.

The variant ADH1B*2 decreases vmax, resulting in slower conversion of ethanol to acetaldehyde. Signup and view all the answers

ALDH2*2 is a variant that increases acetaldehyde.

ALDH2*2 is a variant that increases acetaldehyde. Signup and view all the answers

Having both ADH1B2 and ALDH22 variants would cause a person to feel effects of alcohol much faster.

Having both ADH1B2 and ALDH22 variants would cause a person to feel effects of alcohol much faster. Signup and view all the answers

Disulfiram (Antabuse) inhibits aldehyde dehydrogenase, evoking unpleasant acetaldehyde syndrome when drinking.

Disulfiram (Antabuse) inhibits aldehyde dehydrogenase. Signup and view all the answers

During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.

Alcohol is absorbed faster in the brain than in the blood Signup and view all the answers

During elimination, alcohol concentrations in blood are higher than alcohol concentrations in the brain.

Alcohol is eliminated faster from the blood than from the brain Signup and view all the answers

Blood alcohol does not exactly reflect psychomotor impairment.

Blood alcohol is only partially indicative of psychomotor impairment Signup and view all the answers

The variant ADH1B*2 increases vmax which means faster conversion of ethanol to acetaldehyde.

Speeds up the conversion of ethanol to acetaldehyde Signup and view all the answers

ALDH2*2 is a variant that increases acetaldehyde.

Increases acetaldehyde levels Signup and view all the answers

Having both the ADH1B2 and ALDH22 variants would cause the person to feel effects much faster.

Speeds up the effects of alcohol Signup and view all the answers

Which medication is a weak NMDA receptor antagonist and GABAA agonist?

Acamprosate (Compral) Signup and view all the answers

Visceral vs

Podcast Beta

Questions and Answers

Which of the following drugs inhibits the reuptake of both norepinephrine (NE) and dopamine (DA)?

Which receptor does THC act as a partial agonist at?

Which of the following drugs is an NMDA antagonist?

Which receptor does nicotine selectively agonize?

Which of the following is NOT a characteristic of tolerance?

Which of the following is a major structure of hallucinogens?

Which type of pain is characterized by deep, aching, and poorly localized sensations?

What is the recommended maximum daily intake of acetaminophen to avoid hepatotoxicity?

Which of the following is a long-term benefit of quitting smoking?

Which enzyme is induced when actively smoking and can affect drug metabolism?

Which vitamin is important to prevent Wernicke-Korsakoff syndrome during alcohol withdrawal treatment?

Which medication used for alcohol dependence can cause diarrhea as a common side effect?

What is the recommended dosing of Disulfiram (Antabuse) for alcohol dependence?

Which medication has a ceiling effect on respiratory depression and for analgesia?

Which medication should be used with caution when transferring from a pure agonist to it due to the risk of precipitated withdrawal?

Which medication is no longer used due to the risk of accumulation of the active metabolite, normaperedine, which can cause seizures in patients with impaired renal function?

Which class of medications is used in fibromyalgia, and if contraindicated, Duloxetine can be used as an alternative?

Which medication class should be avoided in older adults, patients with glaucoma, enlarged prostate, and seizure disorder due to their anticholinergic effects?

When converting to another opioid, what adjustment should be made to the dose to account for incomplete tolerance?

Which opioid has a long half-life and is lipophilic, making it dangerous at initiation due to the potential accumulation and risk of respiratory depression?

What should be used to control breakthrough pain, and at what dose relative to the daily dose?

Which medication class should not be used together with benzodiazepines due to the risk of respiratory depression?

During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.

Peak brain alcohol concentration is achieved at 15 minutes. Peak blood alcohol concentration is achieved at 75 minutes.

Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) have considerable polymorphisms.

The variant ADH1B*2 increases vmax, resulting in faster conversion of ethanol to acetaldehyde.

ALDH2*2 is a variant that increases acetaldehyde.

Having both ADH1B2 and ALDH22 variants would cause a person to feel effects of alcohol much faster.

Disulfiram (Antabuse) inhibits aldehyde dehydrogenase, evoking unpleasant acetaldehyde syndrome when drinking.

During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.

During elimination, alcohol concentrations in blood are higher than alcohol concentrations in the brain.

Blood alcohol does not exactly reflect psychomotor impairment.

The variant ADH1B*2 increases vmax which means faster conversion of ethanol to acetaldehyde.

ALDH2*2 is a variant that increases acetaldehyde.

Having both the ADH1B2 and ALDH22 variants would cause the person to feel effects much faster.

Which medication is a weak NMDA receptor antagonist and GABAA agonist?

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