Podcast
Questions and Answers
Which of the following drugs inhibits the reuptake of both norepinephrine (NE) and dopamine (DA)?
Which of the following drugs inhibits the reuptake of both norepinephrine (NE) and dopamine (DA)?
- Ketamine
- THC
- Bupropion (Zyban) (correct)
- Xylazine
Which receptor does THC act as a partial agonist at?
Which receptor does THC act as a partial agonist at?
- kappa receptor
- Alpha-2
- CB1R (correct)
- nAChR
Which of the following drugs is an NMDA antagonist?
Which of the following drugs is an NMDA antagonist?
- Xylazine
- Ketamine and PCP (correct)
- Bupropion (Zyban)
- THC
Which receptor does nicotine selectively agonize?
Which receptor does nicotine selectively agonize?
Which of the following is NOT a characteristic of tolerance?
Which of the following is NOT a characteristic of tolerance?
Which of the following is a major structure of hallucinogens?
Which of the following is a major structure of hallucinogens?
Which type of pain is characterized by deep, aching, and poorly localized sensations?
Which type of pain is characterized by deep, aching, and poorly localized sensations?
What is the recommended maximum daily intake of acetaminophen to avoid hepatotoxicity?
What is the recommended maximum daily intake of acetaminophen to avoid hepatotoxicity?
Which of the following is a long-term benefit of quitting smoking?
Which of the following is a long-term benefit of quitting smoking?
Which enzyme is induced when actively smoking and can affect drug metabolism?
Which enzyme is induced when actively smoking and can affect drug metabolism?
Which vitamin is important to prevent Wernicke-Korsakoff syndrome during alcohol withdrawal treatment?
Which vitamin is important to prevent Wernicke-Korsakoff syndrome during alcohol withdrawal treatment?
Which medication used for alcohol dependence can cause diarrhea as a common side effect?
Which medication used for alcohol dependence can cause diarrhea as a common side effect?
What is the recommended dosing of Disulfiram (Antabuse) for alcohol dependence?
What is the recommended dosing of Disulfiram (Antabuse) for alcohol dependence?
Which medication has a ceiling effect on respiratory depression and for analgesia?
Which medication has a ceiling effect on respiratory depression and for analgesia?
Which medication should be used with caution when transferring from a pure agonist to it due to the risk of precipitated withdrawal?
Which medication should be used with caution when transferring from a pure agonist to it due to the risk of precipitated withdrawal?
Which medication is no longer used due to the risk of accumulation of the active metabolite, normaperedine, which can cause seizures in patients with impaired renal function?
Which medication is no longer used due to the risk of accumulation of the active metabolite, normaperedine, which can cause seizures in patients with impaired renal function?
Which class of medications is used in fibromyalgia, and if contraindicated, Duloxetine can be used as an alternative?
Which class of medications is used in fibromyalgia, and if contraindicated, Duloxetine can be used as an alternative?
Which medication class should be avoided in older adults, patients with glaucoma, enlarged prostate, and seizure disorder due to their anticholinergic effects?
Which medication class should be avoided in older adults, patients with glaucoma, enlarged prostate, and seizure disorder due to their anticholinergic effects?
When converting to another opioid, what adjustment should be made to the dose to account for incomplete tolerance?
When converting to another opioid, what adjustment should be made to the dose to account for incomplete tolerance?
Which opioid has a long half-life and is lipophilic, making it dangerous at initiation due to the potential accumulation and risk of respiratory depression?
Which opioid has a long half-life and is lipophilic, making it dangerous at initiation due to the potential accumulation and risk of respiratory depression?
What should be used to control breakthrough pain, and at what dose relative to the daily dose?
What should be used to control breakthrough pain, and at what dose relative to the daily dose?
Which medication class should not be used together with benzodiazepines due to the risk of respiratory depression?
Which medication class should not be used together with benzodiazepines due to the risk of respiratory depression?
During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.
During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.
Peak brain alcohol concentration is achieved at 15 minutes. Peak blood alcohol concentration is achieved at 75 minutes.
Peak brain alcohol concentration is achieved at 15 minutes. Peak blood alcohol concentration is achieved at 75 minutes.
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) have considerable polymorphisms.
Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) have considerable polymorphisms.
The variant ADH1B*2 increases vmax, resulting in faster conversion of ethanol to acetaldehyde.
The variant ADH1B*2 increases vmax, resulting in faster conversion of ethanol to acetaldehyde.
ALDH2*2 is a variant that increases acetaldehyde.
ALDH2*2 is a variant that increases acetaldehyde.
Having both ADH1B2 and ALDH22 variants would cause a person to feel effects of alcohol much faster.
Having both ADH1B2 and ALDH22 variants would cause a person to feel effects of alcohol much faster.
Disulfiram (Antabuse) inhibits aldehyde dehydrogenase, evoking unpleasant acetaldehyde syndrome when drinking.
Disulfiram (Antabuse) inhibits aldehyde dehydrogenase, evoking unpleasant acetaldehyde syndrome when drinking.
During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.
During absorption, alcohol concentration in the brain is greater than alcohol concentration in the blood.
During elimination, alcohol concentrations in blood are higher than alcohol concentrations in the brain.
During elimination, alcohol concentrations in blood are higher than alcohol concentrations in the brain.
Blood alcohol does not exactly reflect psychomotor impairment.
Blood alcohol does not exactly reflect psychomotor impairment.
The variant ADH1B*2 increases vmax which means faster conversion of ethanol to acetaldehyde.
The variant ADH1B*2 increases vmax which means faster conversion of ethanol to acetaldehyde.
ALDH2*2 is a variant that increases acetaldehyde.
ALDH2*2 is a variant that increases acetaldehyde.
Having both the ADH1B2 and ALDH22 variants would cause the person to feel effects much faster.
Having both the ADH1B2 and ALDH22 variants would cause the person to feel effects much faster.
Which medication is a weak NMDA receptor antagonist and GABAA agonist?
Which medication is a weak NMDA receptor antagonist and GABAA agonist?