Viruses: Nature and Characteristics

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Questions and Answers

What is the primary component of a virus's structure that surrounds its nucleic acid?

  • Ribosome
  • Cell membrane
  • Capsid (correct)
  • Cytoplasm

Which characteristic does NOT describe a virus as non-living?

  • They are ultra-microscopic.
  • They cannot reproduce without a host cell.
  • They have metabolic enzymes. (correct)
  • They can be crystallized.

What type of nucleic acid can be found in viruses?

  • Either DNA or RNA (correct)
  • Only RNA
  • Only DNA
  • Both DNA and RNA co-existing

Which scientist concluded that viruses are neither living nor non-living?

<p>Lowff (B)</p> Signup and view all the answers

What is the term used for viruses that have a lipid or lipoprotein outer coat?

<p>Lipovirus (A)</p> Signup and view all the answers

Which characteristic is considered a living characteristic of a virus?

<p>They can mutate and vary. (C)</p> Signup and view all the answers

Which statement about the capsid is true?

<p>It protects the nucleic acid and aids in reproduction. (B)</p> Signup and view all the answers

What is the main reason antibiotics are ineffective against viruses?

<p>Viruses have a unique protein composition. (D)</p> Signup and view all the answers

What constitutes the outer coat of some viruses?

<p>Lipid or lipoprotein (C)</p> Signup and view all the answers

What do biochemists prioritize when studying viruses?

<p>The non-living characteristics of viruses. (A)</p> Signup and view all the answers

Which of the following viruses are classified as DNA viruses?

<p>Vaccinia virus (A)</p> Signup and view all the answers

What shape is the Tobacco mosaic virus (TMV)?

<p>Rod Shaped (A)</p> Signup and view all the answers

What characterizes viruses as obligate intracellular parasites?

<p>They require a host cell for reproduction. (A)</p> Signup and view all the answers

Which type of virus predominantly infects animals?

<p>Animal Virus (C)</p> Signup and view all the answers

Which of the following statements about the structure of viruses is true?

<p>Viruses contain either DNA or RNA and a protein coat. (C)</p> Signup and view all the answers

Which historical figure is associated with the discovery of the yellow fever virus?

<p>Walter Reed (B)</p> Signup and view all the answers

Which of the following is NOT classified as a plant virus?

<p>HIV (B)</p> Signup and view all the answers

What year was the tobacco mosaic virus crystallized, proving its protein and nucleic acid composition?

<p>1935 (C)</p> Signup and view all the answers

What is the main nucleic acid type of RNA viruses?

<p>Single-stranded RNA (D)</p> Signup and view all the answers

What is the size range of viruses as mentioned?

<p>From 8 nm to 300 nm (B)</p> Signup and view all the answers

Which virus is known for being a retrovirus?

<p>HIV (B)</p> Signup and view all the answers

What type of outer membrane does the influenza virus possess?

<p>With outer membrane (D)</p> Signup and view all the answers

What does the term 'acellular' mean in reference to viruses?

<p>They lack a cellular structure. (D)</p> Signup and view all the answers

Which of the following statements about RNA viruses is true?

<p>RNA viruses can cause mainly plant diseases. (C)</p> Signup and view all the answers

Who discovered the silent killer hepatitis C virus?

<p>Hervey J. Alter (A)</p> Signup and view all the answers

In terms of shape, which classification correctly describes the Ebola virus?

<p>Cylindrical (A)</p> Signup and view all the answers

What crucial role does the protein coat play in a virus?

<p>It protects the nucleic acid core. (D)</p> Signup and view all the answers

Which of the following is classified as a bacteriophage?

<p>T2 virus (C)</p> Signup and view all the answers

Flashcards

RNA Virus

Viruses that use RNA as their genetic material.

DNA Virus

Viruses that use DNA as their genetic material.

Bacteriophage

Viruses that infect bacteria. They are a type of DNA virus.

Plant Virus

A virus that infects plants and causes diseases like mosaic viruses.

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Animal Virus

A virus that causes infections in animals.

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Rod-shaped Viruses

The rod-shaped structure of certain viruses like Tobacco Mosaic Virus.

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Spherical Viruses

Viruses with a spherical shape, like Polio and HIV.

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Cubical Viruses

Viruses with a cubical shape, like Herpes.

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Viruses Without Outer Membrane

Viruses that lack an outer membrane, like TMV and Tâ‚‚ virus.

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Viruses with Outer Membrane

Viruses with an outer membrane, like Influenza and HIV.

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What makes viruses unique?

Viruses are obligate intracellular parasites, meaning they can only reproduce inside a host cell. They lack the cellular structure of bacteria and are too small to be seen with a light microscope.

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What is a capsid?

A protein coat that encases and protects the viral nucleic acid. It's the outer layer of the virus.

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What is the nucleic acid core of a virus?

The core of a virus, containing either DNA or RNA. It carries the genetic information needed for viral replication.

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What is the process of viral replication?

The process by which viruses replicate inside a host cell, using the host's resources to create more viruses.

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What is a bacteriophage?

A bacteriophage is a type of virus that specifically infects bacteria.

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Why are viruses considered ultramicroscopic?

They are too small to be seen with a light microscope, and require the use of an electron microscope.

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When was the first documented observation of a virus-borne disease?

The first time a virus-borne disease was noticed, Edward Jenner observed smallpox in 1796.

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When was the AIDS virus discovered?

The discovery of the AIDS virus, a significant milestone in virology, occurred in 1984.

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Acellular Nature of Viruses

Viruses are acellular, meaning they lack a cell membrane, cytoplasm, ribosomes, and other cellular structures.

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Lack of Metabolism

Viruses lack metabolic enzymes, so they cannot perform metabolic processes like respiration or nutrient breakdown. They rely on host cells for these functions.

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Obligate intracellular parasites

Viruses are unable to reproduce independently. They require a host cell to replicate their genetic material and produce new viruses.

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Viral Capsid

Viral capsids are protein shells that surround the viral nucleic acid (DNA or RNA). These shells are composed of protein subunits called capsomeres.

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Capsid Structure and Shape

The arrangement of capsomeres in a viral capsid determines the shape and size of the virus. This structure can be either helical (rod-like) or polyhedral (round).

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Classification of Viruses

Viruses can be classified into different categories based on factors like their genetic material (DNA or RNA), capsid morphology, and the type of host they infect.

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Viral Envelope

Some viruses have an outer envelope composed of lipids, lipoproteins, or carbohydrates. This envelope helps the virus to enter and exit host cells.

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Viral Nucleic Acid

Viral nucleic acid, either DNA or RNA, is the core component of a virus. It carries the genetic information for replicating the virus.

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Viral Proteins

Viral proteins are essential for the virus's survival and replication. They can act as antigens, triggering immune responses in the host, or as enzymes involved in viral replication.

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Mutation and Variation in Viruses

Changes in the genetic material (mutation) or the arrangement of proteins (variation) can occur in viruses, leading to evolution and adaptation.

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Study Notes

Shape of Virus

  • Viruses can have various shapes: rod-like, ring-shaped, tadpole, cylindrical, oval, or polygonal.

Nature of Virus

  • Scientists are uncertain about the nature of viruses.
  • Viruses are neither completely living nor non-living.
  • In 1962, Stanley and Valens said viruses are intermediate between chemical molecules and living cells.
  • In 1974, Salle stated that viruses are substances between living and non-living.

Characteristics of Virus (Non-Living)

  • Viruses are acellular and don't contain mitochondria.
  • Viruses lack metabolic enzymes.
  • They cannot reproduce without a host cell.
  • They cannot be filtered by bacteria filters.
  • They can be crystallized.
  • Outside of a host cell, they are inactive, like chemical particles.
  • Viruses don't have physical growth and do not respond to environmental stimulation.
  • Chemical compounds like acids, bases, and salts have little to no effect on viruses.

Characteristics of Virus (Living)

  • Viruses can reproduce inside host cells.
  • Each virus produces a similar virus.
  • Structurally, viruses have nucleic acid (either DNA or RNA).
  • They are obligate parasites.
  • Viruses have a capability to mutate and change.
  • Viruses have adaptive capabilities.
  • Genetic recombination may occur in viruses.

Structure of Virus

  • Viruses have a centrally placed nucleic acid.
  • A protein sheath surrounds the nucleic acid, called the capsid.
  • The protein molecules in the capsid are arranged in a rod-shaped helix or form a round or polyhedron.
  • The outer surface of the capsid sometimes has spikes.

Chemical Structure of Virus

  • Viruses usually contain either DNA or RNA, but not both.
  • The protein shell protects the nucleic acid.
  • Some viruses have an outer coat made of lipid or lipoprotein.
  • The outer layer surrounding the capsid is called the envelope.
  • The outer coat is vital in some viruses, especially in protecting the nucleic acid during the cold and flu season.

Classification of Virus

  • Based on shape: rod-shaped, spherical, cubic, tadpole, or cylindrical.
  • Based on nucleic acid: DNA or RNA viruses.
  • Based on the outer membrane: enveloped or non-enveloped.
  • Based on the host: plant viruses, animal viruses, bacteriophages (viruses that attack bacteria).
  • Other types include: cyanophages (attack cyanobacteria), mycophages (attack mycoplasma), phytophagans (attack fungi), and zoophages (attack animals).
  • Examples of viruses include: Tobacco mosaic virus (TMV), HIV, influenza, herpes, smallpox, polio, mumps, measles, West Nile virus, and many more.

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