Virology Quiz: Structural Investigations and Detection Methods

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17 Questions

What are Negri bodies composed of?

Rabies virus proteins and RNA

What is the appearance of Guarnieri bodies of Poxvirus?

Pink blobs in the cytoplasm of affected epithelial cells

What is the characteristic feature of Nuclear bodies of adenovirus?

Dense, central intranuclear inclusions

What is the characteristic feature of Nuclear and cytoplasmic bodies of cytomegalovirus?

Characteristic Owl’s eye intranuclear bodies

In which type of cells are Negri bodies typically found?

Neurons

What is the purpose of fluorescence microscopy in detecting viral infections?

To detect a fluorescent dye linked to antibody molecules

What is the term for the formation of giant cells with multiple nuclei due to cell fusion?

Syncytium formation

Which of the following is an example of cytopathic effect caused by poliovirus?

Cell death

What is the term for the process by which viruses alter the growth characteristics of infected cells?

Cell transformation

What is the main purpose of electron microscopy in virology?

To study the morphology of virions

What is the term for the nuclear or cytoplasmic aggregates of virus particles due to viral replication?

Inclusion bodies

What is a characteristic of viruses?

They are obligate intracellular parasites.

What is the purpose of phage typing of bacteria?

To determine bacterial strains.

What is the purpose of Viral Transport Medium (VTM)?

To preserve viral infectivity and prevent specimen drying.

What is the method of virus cultivation using cells that can divide indefinitely?

Tissue culture using continuous cell line (Hela cell).

What is the name of the method used to identify and quantify viruses?

Plaque assay.

What is the term for the viral particles that infect bacteria?

Bacteriophage.

Test your knowledge on structural investigations of cells and virions, as well as detection methods, including fluorescence microscopy and electron microscopy. Learn about cytopathogenic effects, inclusion bodies, and hemadsorption.

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