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Questions and Answers
What is the function of a class II fusion protein during viral entry?
What is the function of a class II fusion protein during viral entry?
- Mediates virus attachment to the host cell
- Induces conformational changes that lead to membrane fusion or penetration (correct)
- Binds to specific receptors on the host cell
- Facilitates viral genome replication inside the cell
In the infectious cycle, which type of cell is the only one capable of taking up a virus particle and replicating it?
In the infectious cycle, which type of cell is the only one capable of taking up a virus particle and replicating it?
- Permissive cell
- Non-functional cell
- Resistant cell
- Susceptible cell (correct)
What is the primary role of a class I fusion protein in viral entry?
What is the primary role of a class I fusion protein in viral entry?
- Facilitates assembly and release of new virions
- Mediates fusion of viral and cellular membranes (correct)
- Stimulates viral mRNA production and translation
- Attaches to specific receptors on the host cell surface
Why are viruses considered obligate intracellular parasites?
Why are viruses considered obligate intracellular parasites?
During viral attachment, what is the significance of step 1 - adhering to the cell surface?
During viral attachment, what is the significance of step 1 - adhering to the cell surface?
What differentiates a permissive cell from a susceptible cell in terms of viral replication?
What differentiates a permissive cell from a susceptible cell in terms of viral replication?
What is the specific receptor in the endosome membrane that the viral fusion protein binds to?
What is the specific receptor in the endosome membrane that the viral fusion protein binds to?
Which type of fusion protein requires proteolytic cleavage to activate for fusion?
Which type of fusion protein requires proteolytic cleavage to activate for fusion?
How are genomes released from non-enveloped viruses like Adenovirus?
How are genomes released from non-enveloped viruses like Adenovirus?
Which virus requires a low pH environment for fusion to occur?
Which virus requires a low pH environment for fusion to occur?
What allows some viruses to breach the strong cell wall of bacterial cells during infection?
What allows some viruses to breach the strong cell wall of bacterial cells during infection?
Why do plant viruses require assistance from external trauma for entry into plant cells?
Why do plant viruses require assistance from external trauma for entry into plant cells?
What is the main mechanism of entry for influenza virus into host cells?
What is the main mechanism of entry for influenza virus into host cells?
Which type of fusion protein is mostly α-helical and forms trimers?
Which type of fusion protein is mostly α-helical and forms trimers?
In acid-catalyzed membrane fusion, what does the hemagglutinin (HA) protein of influenza virus undergo?
In acid-catalyzed membrane fusion, what does the hemagglutinin (HA) protein of influenza virus undergo?
Which type of fusion proteins are mostly β-sheet and form dimers parallel to the membrane?
Which type of fusion proteins are mostly β-sheet and form dimers parallel to the membrane?
Which type of sialic acid is preferentially bound by human strains of influenza viruses?
Which type of sialic acid is preferentially bound by human strains of influenza viruses?
What is the key event that mediates the fusion of viral and host cell membranes during viral entry?
What is the key event that mediates the fusion of viral and host cell membranes during viral entry?
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