Questions and Answers
What is a brand name for Vilazodone?
What class does Vilazodone belong to?
SPARI
What is Vilazodone commonly prescribed for?
Major depressive disorder; Off label for anxiety; OCD
Are there any tests required for healthy individuals taking Vilazodone?
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What are some noticeable side effects of Vilazodone?
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Weight gain is a common side effect of Vilazodone.
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Sedation is a frequent side effect of Vilazodone.
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What is the usual dosage range for Vilazodone?
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What are the dosage forms of Vilazodone?
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To start Vilazodone, an initial dose of ______ mg/day is recommended.
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How should Vilazodone be taken?
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What is the recommended method for stopping Vilazodone?
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No dose adjustment is necessary for patients with renal impairment taking Vilazodone.
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Vilazodone has been studied extensively in patients with severe hepatic impairment.
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Vilazodone has shown significant effects on heart rate and blood pressure.
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Is there a dose adjustment necessary for elderly patients taking Vilazodone?
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The safety and efficacy of Vilazodone have been established for children.
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Vilazodone is classified as a Risk C medication during pregnancy.
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Study Notes
Vilazodone Overview
- Vilazodone is marketed under the brand name Viibryd and is classified as an SPARI (Serotonin Partial Agonist and Reuptake Inhibitor).
Indications
- Approved by the FDA for the treatment of major depressive disorder.
- Off-label uses include anxiety and obsessive-compulsive disorder (OCD).
Testing and Monitoring
- No specific tests required for healthy individuals taking Vilazodone.
Side Effects
- Common noticeable side effects include nausea, diarrhea, vomiting, insomnia, and dizziness.
- Weight gain and sedation are unusual side effects.
Dosage Information
- The standard dosage range is 40 mg per day.
- Available in tablet forms of 10 mg, 20 mg, and 40 mg.
- Dosage initiation begins at 10 mg/day, increasing to 20 mg after one week, and then to 40 mg after another week; should be taken with food.
Discontinuation
- Tapering off the medication is recommended to prevent withdrawal reactions. Generally, a 50% dose reduction for 3 days followed by another 50% reduction for 3 days is effective.
Special Populations
- Renal Impairment: No dose adjustment necessary.
- Hepatic Impairment: No adjustment needed for mild to moderate impairment; severe impairment has not been specifically studied.
- Cardiac Impairment: Not systematically evaluated; has shown no significant effects on blood pressure, heart rate, or QT intervals in controlled trials.
- Elderly: No dose adjustment required; some may better tolerate lower doses; there is a reduced risk of suicidality with antidepressants compared to placebo in adults aged 65 and older.
- Children: Safety and efficacy not established; use with caution due to potential bipolar disorder and suicidal ideation risks; parents or guardians should be informed of these risks.
- Pregnancy: Classified as Risk C; some animal studies indicate adverse effects, but no controlled human studies are available.
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Test your knowledge on Vilazodone with these flashcards. This quiz covers its brand names, class, common prescriptions, and notable side effects. Perfect for students or anyone interested in pharmacology.
