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Questions and Answers
What is a brand name for Vilazodone?
What is a brand name for Vilazodone?
What class does Vilazodone belong to?
What class does Vilazodone belong to?
SPARI
What is Vilazodone commonly prescribed for?
What is Vilazodone commonly prescribed for?
Major depressive disorder; Off label for anxiety; OCD
Are there any tests required for healthy individuals taking Vilazodone?
Are there any tests required for healthy individuals taking Vilazodone?
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What are some noticeable side effects of Vilazodone?
What are some noticeable side effects of Vilazodone?
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Weight gain is a common side effect of Vilazodone.
Weight gain is a common side effect of Vilazodone.
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Sedation is a frequent side effect of Vilazodone.
Sedation is a frequent side effect of Vilazodone.
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What is the usual dosage range for Vilazodone?
What is the usual dosage range for Vilazodone?
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What are the dosage forms of Vilazodone?
What are the dosage forms of Vilazodone?
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To start Vilazodone, an initial dose of ______ mg/day is recommended.
To start Vilazodone, an initial dose of ______ mg/day is recommended.
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How should Vilazodone be taken?
How should Vilazodone be taken?
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What is the recommended method for stopping Vilazodone?
What is the recommended method for stopping Vilazodone?
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No dose adjustment is necessary for patients with renal impairment taking Vilazodone.
No dose adjustment is necessary for patients with renal impairment taking Vilazodone.
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Vilazodone has been studied extensively in patients with severe hepatic impairment.
Vilazodone has been studied extensively in patients with severe hepatic impairment.
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Vilazodone has shown significant effects on heart rate and blood pressure.
Vilazodone has shown significant effects on heart rate and blood pressure.
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Is there a dose adjustment necessary for elderly patients taking Vilazodone?
Is there a dose adjustment necessary for elderly patients taking Vilazodone?
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The safety and efficacy of Vilazodone have been established for children.
The safety and efficacy of Vilazodone have been established for children.
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Vilazodone is classified as a Risk C medication during pregnancy.
Vilazodone is classified as a Risk C medication during pregnancy.
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Study Notes
Vilazodone Overview
- Vilazodone is marketed under the brand name Viibryd and is classified as an SPARI (Serotonin Partial Agonist and Reuptake Inhibitor).
Indications
- Approved by the FDA for the treatment of major depressive disorder.
- Off-label uses include anxiety and obsessive-compulsive disorder (OCD).
Testing and Monitoring
- No specific tests required for healthy individuals taking Vilazodone.
Side Effects
- Common noticeable side effects include nausea, diarrhea, vomiting, insomnia, and dizziness.
- Weight gain and sedation are unusual side effects.
Dosage Information
- The standard dosage range is 40 mg per day.
- Available in tablet forms of 10 mg, 20 mg, and 40 mg.
- Dosage initiation begins at 10 mg/day, increasing to 20 mg after one week, and then to 40 mg after another week; should be taken with food.
Discontinuation
- Tapering off the medication is recommended to prevent withdrawal reactions. Generally, a 50% dose reduction for 3 days followed by another 50% reduction for 3 days is effective.
Special Populations
- Renal Impairment: No dose adjustment necessary.
- Hepatic Impairment: No adjustment needed for mild to moderate impairment; severe impairment has not been specifically studied.
- Cardiac Impairment: Not systematically evaluated; has shown no significant effects on blood pressure, heart rate, or QT intervals in controlled trials.
- Elderly: No dose adjustment required; some may better tolerate lower doses; there is a reduced risk of suicidality with antidepressants compared to placebo in adults aged 65 and older.
- Children: Safety and efficacy not established; use with caution due to potential bipolar disorder and suicidal ideation risks; parents or guardians should be informed of these risks.
- Pregnancy: Classified as Risk C; some animal studies indicate adverse effects, but no controlled human studies are available.
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Test your knowledge on Vilazodone with these flashcards. This quiz covers its brand names, class, common prescriptions, and notable side effects. Perfect for students or anyone interested in pharmacology.