Podcast
Questions and Answers
What is the generic name and class of Victoza?
What is the generic name and class of Victoza?
- Liraglutide and GLP-1 (correct)
- Rosiglitazone and Thiazolidinedione
- Glimepiride and Sulfonylurea
- Metformin and Biguanide
What is the efficacy of Victoza?
What is the efficacy of Victoza?
Effective in lowering sugars in patients with the use of a GLP-1
What is the nature of the clinical data for Victoza?
What is the nature of the clinical data for Victoza?
A 26-week, double-blind, double-dummy, placebo- and active-controlled, 5-armed, parallel trial.
What is the indication for Victoza?
What is the indication for Victoza?
Victoza can cause thyroid cancer.
Victoza can cause thyroid cancer.
List some side effects of Victoza.
List some side effects of Victoza.
What is the initial dosing for Victoza?
What is the initial dosing for Victoza?
How should Victoza be administered?
How should Victoza be administered?
What is the mechanism of action of Victoza?
What is the mechanism of action of Victoza?
What benefit does Victoza provide regarding cardiac events?
What benefit does Victoza provide regarding cardiac events?
Victoza has poor tolerability with nausea and vomiting.
Victoza has poor tolerability with nausea and vomiting.
What is unique about the Victoza pen?
What is unique about the Victoza pen?
What support does the Diabetes Health Coach provide?
What support does the Diabetes Health Coach provide?
What is the purpose of the blood sugar tracker?
What is the purpose of the blood sugar tracker?
Eligible patients can pay more than $25 for their Victoza prescription with the Instant Savings Card.
Eligible patients can pay more than $25 for their Victoza prescription with the Instant Savings Card.
Study Notes
Victoza Overview
- Generic name: Liraglutide; belongs to the GLP-1 drug class.
- Effective in lowering blood sugar levels in patients using GLP-1.
Clinical Study
- Conducted a 26-week, double-blind, double-dummy trial to evaluate efficacy and safety.
- Included five arms comparing Victoza, rosiglitazone, and placebo, all with glimepiride for type 2 diabetes management.
Indications and Benefits
- Approved for adults with type 2 diabetes to reduce A1c and blood sugar levels.
- Proven to lower the risk of cardiac events.
Safety and Risks
- Potential risk of thyroid cancer associated with Victoza.
- Side effects may include headache, dizziness, gastrointestinal issues, and cold-like symptoms.
Dosing Guidelines
- Initial dose is 0.6 mg per day for one week to mitigate gastrointestinal distress.
- After one week, the dosage should be increased to 1.2 mg for better glycemic control.
Administration
- Administered subcutaneously once daily.
Mechanism of Action
- Liraglutide acts as a long-acting GLP-1 receptor agonist, stimulating insulin secretion by binding to GLP-1 receptors.
Impact on Mortality
- Has the potential to reduce the risk of death from cardiac events in patients with type 2 diabetes.
Patient Tolerability
- Nausea and vomiting are common tolerability challenges in initial treatment phases.
Delivery Devices
- Utilizes a prefilled, disposable Victoza pen that can be dialed to the prescribed dose.
Patient Support
- Offers the Diabetes Health Coach for live and digital support between doctor visits.
- Blood sugar tracker available for patients to share progress with healthcare providers.
Financial Assistance
- Eligible patients can utilize the Victoza Instant Savings Card, limiting costs to $25 for prescriptions.
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Description
Test your knowledge about Victoza, including its generic name, drug class, and clinical efficacy. These flashcards will help you understand the important clinical data and effectiveness of Liraglutide as a GLP-1 receptor agonist. Perfect for medical students and healthcare professionals.
