Victoza Flashcards

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Questions and Answers

What is the generic name and class of Victoza?

  • Liraglutide and GLP-1 (correct)
  • Rosiglitazone and Thiazolidinedione
  • Glimepiride and Sulfonylurea
  • Metformin and Biguanide

What is the efficacy of Victoza?

Effective in lowering sugars in patients with the use of a GLP-1

What is the nature of the clinical data for Victoza?

A 26-week, double-blind, double-dummy, placebo- and active-controlled, 5-armed, parallel trial.

What is the indication for Victoza?

<p>Indicated in adults with type 2 diabetes to lower A1c and blood sugar and also lowers the risk of cardiac events.</p> Signup and view all the answers

Victoza can cause thyroid cancer.

<p>True (A)</p> Signup and view all the answers

List some side effects of Victoza.

<p>Headache, dizziness, upset stomach, loss of appetite, nausea, vomiting, diarrhea, constipation, cold symptoms, back pain, tired feeling, mild skin rash.</p> Signup and view all the answers

What is the initial dosing for Victoza?

<p>0.6 mg per day for one week.</p> Signup and view all the answers

How should Victoza be administered?

<p>Subcutaneously once daily.</p> Signup and view all the answers

What is the mechanism of action of Victoza?

<p>Liraglutide is a GLP-1 receptor agonist that stimulates insulin secretion.</p> Signup and view all the answers

What benefit does Victoza provide regarding cardiac events?

<p>Can reduce the risk of death from cardiac events in patients with type 2 diabetes.</p> Signup and view all the answers

Victoza has poor tolerability with nausea and vomiting.

<p>False (B)</p> Signup and view all the answers

What is unique about the Victoza pen?

<p>The prefilled, disposable Victoza pen can be dialed to the prescribed dose.</p> Signup and view all the answers

What support does the Diabetes Health Coach provide?

<p>Live and digital support to guide patients between office visits.</p> Signup and view all the answers

What is the purpose of the blood sugar tracker?

<p>To allow patients to share their progress with healthcare providers.</p> Signup and view all the answers

Eligible patients can pay more than $25 for their Victoza prescription with the Instant Savings Card.

<p>False (B)</p> Signup and view all the answers

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Study Notes

Victoza Overview

  • Generic name: Liraglutide; belongs to the GLP-1 drug class.
  • Effective in lowering blood sugar levels in patients using GLP-1.

Clinical Study

  • Conducted a 26-week, double-blind, double-dummy trial to evaluate efficacy and safety.
  • Included five arms comparing Victoza, rosiglitazone, and placebo, all with glimepiride for type 2 diabetes management.

Indications and Benefits

  • Approved for adults with type 2 diabetes to reduce A1c and blood sugar levels.
  • Proven to lower the risk of cardiac events.

Safety and Risks

  • Potential risk of thyroid cancer associated with Victoza.
  • Side effects may include headache, dizziness, gastrointestinal issues, and cold-like symptoms.

Dosing Guidelines

  • Initial dose is 0.6 mg per day for one week to mitigate gastrointestinal distress.
  • After one week, the dosage should be increased to 1.2 mg for better glycemic control.

Administration

  • Administered subcutaneously once daily.

Mechanism of Action

  • Liraglutide acts as a long-acting GLP-1 receptor agonist, stimulating insulin secretion by binding to GLP-1 receptors.

Impact on Mortality

  • Has the potential to reduce the risk of death from cardiac events in patients with type 2 diabetes.

Patient Tolerability

  • Nausea and vomiting are common tolerability challenges in initial treatment phases.

Delivery Devices

  • Utilizes a prefilled, disposable Victoza pen that can be dialed to the prescribed dose.

Patient Support

  • Offers the Diabetes Health Coach for live and digital support between doctor visits.
  • Blood sugar tracker available for patients to share progress with healthcare providers.

Financial Assistance

  • Eligible patients can utilize the Victoza Instant Savings Card, limiting costs to $25 for prescriptions.

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