Victoza Flashcards

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Questions and Answers

What is the generic name and class of Victoza?

Liraglutide and GLP-1 (correct)

Rosiglitazone and Thiazolidinedione

Glimepiride and Sulfonylurea

Metformin and Biguanide

What is the efficacy of Victoza?

Effective in lowering sugars in patients with the use of a GLP-1

What is the nature of the clinical data for Victoza?

A 26-week, double-blind, double-dummy, placebo- and active-controlled, 5-armed, parallel trial.

What is the indication for Victoza?

Indicated in adults with type 2 diabetes to lower A1c and blood sugar and also lowers the risk of cardiac events. Signup and view all the answers

Victoza can cause thyroid cancer.

True Signup and view all the answers

List some side effects of Victoza.

Headache, dizziness, upset stomach, loss of appetite, nausea, vomiting, diarrhea, constipation, cold symptoms, back pain, tired feeling, mild skin rash. Signup and view all the answers

What is the initial dosing for Victoza?

0.6 mg per day for one week. Signup and view all the answers

How should Victoza be administered?

Subcutaneously once daily. Signup and view all the answers

What is the mechanism of action of Victoza?

Liraglutide is a GLP-1 receptor agonist that stimulates insulin secretion. Signup and view all the answers

What benefit does Victoza provide regarding cardiac events?

Can reduce the risk of death from cardiac events in patients with type 2 diabetes. Signup and view all the answers

Victoza has poor tolerability with nausea and vomiting.

False Signup and view all the answers

What is unique about the Victoza pen?

The prefilled, disposable Victoza pen can be dialed to the prescribed dose. Signup and view all the answers

What support does the Diabetes Health Coach provide?

Live and digital support to guide patients between office visits. Signup and view all the answers

What is the purpose of the blood sugar tracker?

To allow patients to share their progress with healthcare providers. Signup and view all the answers

Eligible patients can pay more than $25 for their Victoza prescription with the Instant Savings Card.

False Signup and view all the answers

Study Notes

Victoza Overview

Generic name: Liraglutide; belongs to the GLP-1 drug class.
Effective in lowering blood sugar levels in patients using GLP-1.

Clinical Study

Conducted a 26-week, double-blind, double-dummy trial to evaluate efficacy and safety.
Included five arms comparing Victoza, rosiglitazone, and placebo, all with glimepiride for type 2 diabetes management.

Indications and Benefits

Approved for adults with type 2 diabetes to reduce A1c and blood sugar levels.
Proven to lower the risk of cardiac events.

Safety and Risks

Potential risk of thyroid cancer associated with Victoza.
Side effects may include headache, dizziness, gastrointestinal issues, and cold-like symptoms.

Dosing Guidelines

Initial dose is 0.6 mg per day for one week to mitigate gastrointestinal distress.
After one week, the dosage should be increased to 1.2 mg for better glycemic control.

Administration

Administered subcutaneously once daily.

Mechanism of Action

Liraglutide acts as a long-acting GLP-1 receptor agonist, stimulating insulin secretion by binding to GLP-1 receptors.

Impact on Mortality

Has the potential to reduce the risk of death from cardiac events in patients with type 2 diabetes.

Patient Tolerability

Nausea and vomiting are common tolerability challenges in initial treatment phases.

Delivery Devices

Utilizes a prefilled, disposable Victoza pen that can be dialed to the prescribed dose.

Patient Support

Offers the Diabetes Health Coach for live and digital support between doctor visits.
Blood sugar tracker available for patients to share progress with healthcare providers.

Financial Assistance

Eligible patients can utilize the Victoza Instant Savings Card, limiting costs to $25 for prescriptions.

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Description

Test your knowledge about Victoza, including its generic name, drug class, and clinical efficacy. These flashcards will help you understand the important clinical data and effectiveness of Liraglutide as a GLP-1 receptor agonist. Perfect for medical students and healthcare professionals.