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Questions and Answers
What type of toxins primarily affect the intestinal mucosa and cause hypersecretory diarrhea in neonatal farm animals?
What type of toxins primarily affect the intestinal mucosa and cause hypersecretory diarrhea in neonatal farm animals?
- Metabolic toxins
- Endotoxins
- Exotoxins (correct)
- Neurotoxins
What are endotoxins primarily made of?
What are endotoxins primarily made of?
- Nucleic acids
- Lipopolysaccharides (correct)
- Proteins
- Carbohydrates
What is the major consequence of endotoxins being released into the bloodstream?
What is the major consequence of endotoxins being released into the bloodstream?
- Coughing
- Muscle spasms
- Morbidity and mortality (correct)
- Skin rashes
What condition can occur due to anaphylaxis from repeated biological preparations?
What condition can occur due to anaphylaxis from repeated biological preparations?
What is the primary cause of metabolic toxins in the body?
What is the primary cause of metabolic toxins in the body?
Which of the following reactions is least likely to cause anaphylaxis upon the first injection?
Which of the following reactions is least likely to cause anaphylaxis upon the first injection?
What causes edema in tissues?
What causes edema in tissues?
Where does endotoxin gain access to the bloodstream primarily?
Where does endotoxin gain access to the bloodstream primarily?
What is one condition that can lead to insufficient heat production in animals?
What is one condition that can lead to insufficient heat production in animals?
Which type of fever is characterized by little change in elevated temperature during a 24-hour period?
Which type of fever is characterized by little change in elevated temperature during a 24-hour period?
What condition could lead to excessive heat loss in an animal?
What condition could lead to excessive heat loss in an animal?
What is a potential cause of hyperthermia?
What is a potential cause of hyperthermia?
Which type of fever displays recurring elevated temperature separated by intervals of normal temperature?
Which type of fever displays recurring elevated temperature separated by intervals of normal temperature?
Which of the following conditions may contribute to a decrease in skeletal muscle contraction?
Which of the following conditions may contribute to a decrease in skeletal muscle contraction?
What is a characteristic of transient fever?
What is a characteristic of transient fever?
Which of the following is NOT a cause of hyperthermia?
Which of the following is NOT a cause of hyperthermia?
Which condition is primarily associated with increased hydrostatic pressure in capillaries?
Which condition is primarily associated with increased hydrostatic pressure in capillaries?
What is one of the primary signs of chronic toxemia?
What is one of the primary signs of chronic toxemia?
What major cause contributes to dehydration?
What major cause contributes to dehydration?
What condition is characterized by an increased body temperature that is independent of ambient conditions?
What condition is characterized by an increased body temperature that is independent of ambient conditions?
Which clinical sign indicates acute overhydration?
Which clinical sign indicates acute overhydration?
Which of the following decreases as a result of decreased plasma oncotic pressure?
Which of the following decreases as a result of decreased plasma oncotic pressure?
Which of the following is a cause of dehydration related to fever?
Which of the following is a cause of dehydration related to fever?
What is a common manifestation of toxic or septic shock due to toxin formation?
What is a common manifestation of toxic or septic shock due to toxin formation?
What is septicemia primarily associated with?
What is septicemia primarily associated with?
Which condition is associated with abnormal depletion of body fluids?
Which condition is associated with abnormal depletion of body fluids?
Which toxic substance can lead to atypical fever due to poisoning?
Which toxic substance can lead to atypical fever due to poisoning?
Which factor is NOT typically associated with the regulation of fever?
Which factor is NOT typically associated with the regulation of fever?
Which sign indicates both acute and chronic toxemia?
Which sign indicates both acute and chronic toxemia?
What is a major risk for newborn farm animals that fail to consume colostrum in the first 24 hours?
What is a major risk for newborn farm animals that fail to consume colostrum in the first 24 hours?
Which condition is associated with viruses invading the systemic circulation?
Which condition is associated with viruses invading the systemic circulation?
What is a common cause of morbidity in horses related to temperature regulation?
What is a common cause of morbidity in horses related to temperature regulation?
What condition is primarily characterized by a reduction in circulating blood volume due to rapid loss of blood?
What condition is primarily characterized by a reduction in circulating blood volume due to rapid loss of blood?
Which of the following is a common cause of acidosis?
Which of the following is a common cause of acidosis?
What defines obstructive shock?
What defines obstructive shock?
Hypocalcemia is associated with which of the following conditions?
Hypocalcemia is associated with which of the following conditions?
What primarily causes alkalosis?
What primarily causes alkalosis?
Which electrolyte abnormality would NOT typically be associated with hypophosphatemia?
Which electrolyte abnormality would NOT typically be associated with hypophosphatemia?
What physiological reaction primarily leads to pain perception?
What physiological reaction primarily leads to pain perception?
What could potentially cause hypomagnesemia?
What could potentially cause hypomagnesemia?
Which condition is most commonly associated with hyponatremia?
Which condition is most commonly associated with hyponatremia?
What is a possible consequence of hyperthermia in severe endotoxemia?
What is a possible consequence of hyperthermia in severe endotoxemia?
Which electrolyte imbalance is likely associated with muscular weakness and recumbency?
Which electrolyte imbalance is likely associated with muscular weakness and recumbency?
What triggers shock in the context of severe endotoxemia?
What triggers shock in the context of severe endotoxemia?
Hypochloremia is most likely to occur as a result of which condition?
Hypochloremia is most likely to occur as a result of which condition?
Which sign would be least expected in a patient suffering from severe endotoxemia?
Which sign would be least expected in a patient suffering from severe endotoxemia?
What is a major electrolyte of concern during severe endotoxemia?
What is a major electrolyte of concern during severe endotoxemia?
Which symptom indicates the progression of severe endotoxemia toward shock?
Which symptom indicates the progression of severe endotoxemia toward shock?
Flashcards
Hyperthermia
Hyperthermia
A condition where the body's core temperature rises above its normal set point. This can be caused by exposure to excessive heat, prolonged physical exertion, or underlying medical conditions.
Exposure to Cold Air
Exposure to Cold Air
A type of hyperthermia caused by exposure to cold air temperatures. The animal's inability to generate enough heat leads to a decrease in core body temperature.
Remittent Fever
Remittent Fever
A fever that fluctuates throughout the day but never reaches normal body temperature.
Sustained/Continuous Fever
Sustained/Continuous Fever
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Transient Fever
Transient Fever
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Intermittent Fever
Intermittent Fever
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Neurogenic Hyperthermia
Neurogenic Hyperthermia
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Prolonged, Severe Muscular Exertion
Prolonged, Severe Muscular Exertion
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Fever (Pyrexia)
Fever (Pyrexia)
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Bacteremia
Bacteremia
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Viremia
Viremia
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Septicemia
Septicemia
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Enterotoxins
Enterotoxins
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Endotoxins
Endotoxins
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How Endotoxins Reach the Bloodstream
How Endotoxins Reach the Bloodstream
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Metabolic Toxins
Metabolic Toxins
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Anaphylaxis
Anaphylaxis
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Edema
Edema
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Anaphylactic Shock
Anaphylactic Shock
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Factors Contributing to Anaphylaxis
Factors Contributing to Anaphylaxis
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Hyperthermia followed by Hypothermia
Hyperthermia followed by Hypothermia
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Tachycardia Followed by Decreased Cardiac Output
Tachycardia Followed by Decreased Cardiac Output
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Decreased Systemic Blood Pressure
Decreased Systemic Blood Pressure
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Cool Skin and Extremities
Cool Skin and Extremities
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Electrolyte Imbalances
Electrolyte Imbalances
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Shock (Hypovolemic, Hemorrhagic, Maldistributive and Obstructive Shock)
Shock (Hypovolemic, Hemorrhagic, Maldistributive and Obstructive Shock)
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Diarrhea
Diarrhea
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Congested mucosa with Increased CRT
Congested mucosa with Increased CRT
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Hypovolemic Shock
Hypovolemic Shock
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Hemorrhagic Shock
Hemorrhagic Shock
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Maldistributive Shock
Maldistributive Shock
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Obstructive Shock
Obstructive Shock
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Acidosis
Acidosis
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Alkalosis
Alkalosis
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Pain
Pain
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Corticosteroid Side Effects
Corticosteroid Side Effects
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Study Notes
Manifestation of Clinical Diseases
- A disease is an inability to perform physiological functions at normal levels, even with adequate nutrition and environment.
- Systemic alterations are common during disease processes.
- Infections can manifest locally or systemically, gradually developing over days to years.
- Infections can affect multiple organs, and symptoms may resolve with treatment.
Systemic States
- Hypothermia: Lower than normal body temperature, a major cause of neonatal mortality and morbidity. Causes include excessive heat loss (exposure to cold) and insufficient heat production (low energy reserves, poor feed intake). It can also be a symptom of other diseases.
- Hyperthermia (Heat Stroke/Heat Exhaustion): Increased core body temperature often due to exposure to high environmental temperatures or strenuous exercise. Other contributing factors include neurogenic issues, dehydration, excessive activity, and various poisonings.
Fever Types
- Septic Fever: Infection with bacteria, viruses, protozoa, or fungi, causing localized or systemic issues (bacteremia, endocarditis, septicemia).
- Aseptic Fever: Fever associated with aseptic wounds, likely due to leukocyte breakdown or tissue damage.
- Chemical Fever: Fever caused by substances like foreign proteins or dinitrophenols.
- Surgical Fever: Fever due to tissue breakdown and inflammation (muscle damage, hemolytic crises, infarctions, neoplasms).
Forms of Fever
- Transient: Body temperature fluctuates around normal during the day.
- Sustained/Continuous: Little change in temperature over a 24-hour period (not exceeding 1°C variation).
- Remittent: Temperature fluctuates but never reaches normal levels.
- Intermittent: Recurring fever attacks with periods of normal temperature in between.
- Atypical: Irregular temperature variations.
Septicemia and Viremia
- Septicemia: Acute invasion of the bloodstream by pathogenic bacteria, often with septic shock and possible localization in organs.
- Bacteremia: Bacteria in the bloodstream, not associated with clinical signs and not necessarily causing sepsis or shock.
- Viremia: Pathogenic viruses in the bloodstream potentially affecting tissues.
Toxemia and Endotoxemia
- Toxemia: Widespread host response to toxins from bacteria or tissue damage; detectable toxins in the blood are crucial for diagnosis.
- Two classifications of toxins are: 1) Antigenic toxins which are often produced by bacteria and helminth parasites and stimulate antibody production and 2) Metabolic toxin toxins that result from incomplete elimination or abnormal metabolism of body materials
Fever (Pyrexia)
- Increased body temperature independent of environmental conditions.
- A combination of hyperthermia and infection/inflammation, rising from a higher temperature setpoint by the body.
- Mediated by endogenous pyrogens (produced by immune cells) and exogenous pyrogens (bacteria, viruses, toxins).
Pain (Nociception)
- Pain is a distressing sensation resulting from stimulation of specific nerve endings. There are three types: cutaneous, visceral, and somatic.
Stress
- A systemic state resulting from long-term exposure to stressors.
- May lead to psychosomatic diseases, increased susceptibility to infections, and decreased productivity in animals.
Localized Infections
- Abscess: Localized collection of pus, often occurring in response to infection or foreign material.
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