Podcast
Questions and Answers
Why might a veterinarian be cautious about prescribing certain analgesics to dogs, considering their metabolic processes?
Why might a veterinarian be cautious about prescribing certain analgesics to dogs, considering their metabolic processes?
- Dogs have a less effective metabolism of certain analgesics compared to cats. (correct)
- Dogs have more sensitive pain receptors, making it harder to find an effective dose.
- Dogs tend to be more active, increasing the risk of injury while medicated.
- Dogs generally have higher body fat percentages, leading to slower drug absorption.
What is the study of how drugs move into, through, and out of the body, influencing dosage and frequency?
What is the study of how drugs move into, through, and out of the body, influencing dosage and frequency?
- Pharmacovigilance
- Pharmacokinetics (correct)
- Pharmacodynamics
- Pharmacognosy
Which of the following best describes pharmacodynamics?
Which of the following best describes pharmacodynamics?
- The process by which the body breaks down and eliminates drugs.
- The method of drug delivery that maximizes bioavailability.
- The study of how drugs produce their effects on the body. (correct)
- The study of how drug concentrations change over time in the body.
A drug administered orally has a lower concentration in the systemic circulation than when administered intravenously. What term describes this phenomenon?
A drug administered orally has a lower concentration in the systemic circulation than when administered intravenously. What term describes this phenomenon?
What property of a drug determines how readily it will bind to its target receptor?
What property of a drug determines how readily it will bind to its target receptor?
A drug binds to a receptor and triggers a cellular response. What term describes the drug's ability to initiate this response?
A drug binds to a receptor and triggers a cellular response. What term describes the drug's ability to initiate this response?
Which two catecholamines are primarily responsible for mediating the effects of the sympathetic nervous system?
Which two catecholamines are primarily responsible for mediating the effects of the sympathetic nervous system?
What potent vasoconstrictor, vital for blood pressure regulation, is activated by ACE (angiotensin-converting enzyme)?
What potent vasoconstrictor, vital for blood pressure regulation, is activated by ACE (angiotensin-converting enzyme)?
Which hormone plays a primary role in regulating sodium reabsorption in the kidneys, impacting blood volume and pressure?
Which hormone plays a primary role in regulating sodium reabsorption in the kidneys, impacting blood volume and pressure?
How do pharmacokinetics and pharmacodynamics differ in their focus within the realm of drug action?
How do pharmacokinetics and pharmacodynamics differ in their focus within the realm of drug action?
What is the type of cardiac drugs that have the recognizable "pail" at the end?
What is the type of cardiac drugs that have the recognizable "pail" at the end?
This receptor, when stimulated increases the HR.
This receptor, when stimulated increases the HR.
What drug is a venous dilator that is applied as a cream?
What drug is a venous dilator that is applied as a cream?
This drug is a potassium sparing diuretic.
This drug is a potassium sparing diuretic.
What drug has been indicated with DCM in dogs and Mitral valve disease in cats?
What drug has been indicated with DCM in dogs and Mitral valve disease in cats?
This drug is a centrally acting opioid antitussive; the only FDA approved Veterinary product for cough.
This drug is a centrally acting opioid antitussive; the only FDA approved Veterinary product for cough.
What is the term that describes a drug made by coming an opioid drug with a tranquilizer or sedative?
What is the term that describes a drug made by coming an opioid drug with a tranquilizer or sedative?
What drug is a mixed strong kappa-agonist opioid that also has weak mu-agonist or u-antagonist activity; ceiling effect; approved for use as a canine antitussive?
What drug is a mixed strong kappa-agonist opioid that also has weak mu-agonist or u-antagonist activity; ceiling effect; approved for use as a canine antitussive?
Flashcards
Analgesic Disadvantage in Dogs
Analgesic Disadvantage in Dogs
Dogs metabolize some analgesics less effectively than cats, leading to potential toxicity.
Pharmacokinetics
Pharmacokinetics
The study of how drugs move through the body, including absorption, distribution, metabolism, and excretion.
Pharmacodynamics
Pharmacodynamics
The study of how drugs produce their effects on the body, including mechanism of action and effects.
Bioavailability
Bioavailability
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Affinity
Affinity
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Intrinsic Activity
Intrinsic Activity
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Sympathetic Catecholamines
Sympathetic Catecholamines
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Angiotensin II
Angiotensin II
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Aldosterone
Aldosterone
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Study Notes
- A significant disadvantage of using analgesics in dogs compared to cats is that dogs have less effective metabolism of certain analgesics.
- Pharmacokinetics refers to the study of how drugs move into, through, and out of the body.
- Pharmacodynamics refers to the study of how drugs produce their effects on the body.
- Bioavailability describes the concentration of a drug administered that actually makes it into systemic circulation.
- Affinity describes the ability of a drug molecule to combine with a receptor.
- Intrinsic activity describes the ability of a drug molecule to cause an effect on a cell once it has combined with the cell receptor
- Epinephrine and norepinephrine are the two catecholamines released by the sympathetic nervous system that produce its effects.
- Angiotensin II, converted to its active form by ACE, is the body's most potent vasoconstrictor.
- Aldosterone is the hormone that regulates sodium reabsorption from urine.
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