Veterinary Pathology: Necrosis and Gangrene

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What is a characteristic of coagulative necrosis?

Autolysis of cells

Formation of fibrin (correct)

Inflammation

Loss of tissue architecture

What is a common location for coagulative necrosis?

Skin and pancreas

Brain and heart

Lungs

Kidney, liver, and muscles (correct)

What can cause coagulative necrosis?

Trauma and nutritional deficiencies

Infections, ischemia, and mild irritants (correct)

Bacterial infections and cancer

Viral infections

What is a result of coagulative necrosis?

Preservation of tissue architecture Signup and view all the answers

What type of necrosis is characterized by the coagulation of necrotic tissue?

Coagulative necrosis Signup and view all the answers

What color does the organ become due to coagulative necrosis?

Gray/white Signup and view all the answers

Which type of necrosis is characterized by the presence of firm, dry, and cheesy consistency?

Caseative/caseous necrosis Signup and view all the answers

What is the cause of liquefactive necrosis?

Enzymatic dissolution of cells by intracellular hydrolases Signup and view all the answers

What is the microscopic feature of coagulative necrosis?

Absence of nucleus or pyknotic nucleus Signup and view all the answers

What is the etiology of caseative/caseous necrosis?

Chronic infections such as Mycobacterium tuberculosis Signup and view all the answers

What is the characteristic of the dead tissue in caseative/caseous necrosis?

Firm and dry Signup and view all the answers

What is the characteristic of pyknosis?

Condensation of chromatin material, with a dark, reduced, and deeply stained nucleus Signup and view all the answers

What is the term for physiological cell death after completion of its function?

Necrobiosis Signup and view all the answers

What is the type of necrosis characterized by the coagulation of necrotic tissue due to the presence of an enzyme that produces fibrin?

Coagulative necrosis Signup and view all the answers

What is the gross appearance of necrotic tissue?

Pale, soft, friable, and sharply demarcated from viable tissue Signup and view all the answers

What is the etiology of coagulative necrosis?

Infections, ischemia, and mild irritants Signup and view all the answers

What is karyolysis?

Dissolution of nucleus into small fragments Signup and view all the answers

Which type of necrosis is characterized by the presence of a cavity?

Liquefactive necrosis Signup and view all the answers

What is the primary cause of fat necrosis?

Pancreatic juice leakage Signup and view all the answers

What is the term for the death of adipose cells in a living body?

Fat necrosis Signup and view all the answers

What is the purpose of apoptosis in the body?

To control cell number and maintain homeostasis Signup and view all the answers

What is the term for the changes that occur in the nucleus during necrosis?

All of the above Signup and view all the answers

What is the characteristic of the tissue in liquefactive necrosis?

It is soft and cloudy Signup and view all the answers

What is the primary cause of decreased ATP in the body after death?

Hypoxia occurring due to cessation of oxygen supply Signup and view all the answers

What is the characteristic of post-mortem clots in terms of their attachment to endothelium?

They are not attached to the endothelium Signup and view all the answers

What is the primary function of lysosomal enzymes in the process of autolysis?

To digest cells and tissues Signup and view all the answers

What is the difference between red and yellow post-mortem clots?

The distribution of blood components in the clot Signup and view all the answers

What is the primary distinguishing feature of autolysis from putrefaction?

The uniform destruction of cells without inflammatory reaction Signup and view all the answers

What is the source of thrombokinase in post-mortem clotting?

Dying leucocytes and endothelial cells Signup and view all the answers