Podcast
Questions and Answers
What is the estimated prevalence of hypothyroidism in dogs?
What is the estimated prevalence of hypothyroidism in dogs?
Which condition is least likely to be related to hypothyroidism in dogs?
Which condition is least likely to be related to hypothyroidism in dogs?
What common ocular abnormality can be found in canines?
What common ocular abnormality can be found in canines?
What is a potential consequence of bullous retinal detachment in dogs?
What is a potential consequence of bullous retinal detachment in dogs?
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Which of the following does not describe a complication commonly associated with hypothyroidism in dogs?
Which of the following does not describe a complication commonly associated with hypothyroidism in dogs?
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What condition remained unchanged in the untreated eye?
What condition remained unchanged in the untreated eye?
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What does the conclusion suggest about lamellar keratectomy?
What does the conclusion suggest about lamellar keratectomy?
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Which of the following options relates to the surgical approach mentioned?
Which of the following options relates to the surgical approach mentioned?
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What is the implication of corneal lipidosis in the untreated eye?
What is the implication of corneal lipidosis in the untreated eye?
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Which of the following statements is most consistent with the conclusions drawn?
Which of the following statements is most consistent with the conclusions drawn?
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What is the primary cause of the lesions described in the population?
What is the primary cause of the lesions described in the population?
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Which of the following is NOT a subtype of corneal lipidosis?
Which of the following is NOT a subtype of corneal lipidosis?
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What characterizes arcus lipoides corneae?
What characterizes arcus lipoides corneae?
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What types of deposits can cause corneal opacities according to the information?
What types of deposits can cause corneal opacities according to the information?
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The condition that leads to corneal lipidosis is often associated with which other manifestation?
The condition that leads to corneal lipidosis is often associated with which other manifestation?
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What was the main focus of the examination 2 months after the initial presentation?
What was the main focus of the examination 2 months after the initial presentation?
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Which of the following sections was spared from resection during the keratectomy?
Which of the following sections was spared from resection during the keratectomy?
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What does the term 'keratectomy' refer to?
What does the term 'keratectomy' refer to?
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Which statement best describes the relationship between the cornea and the initial examination findings?
Which statement best describes the relationship between the cornea and the initial examination findings?
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What was determined during the examination two months post-surgery?
What was determined during the examination two months post-surgery?
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Which task did Schenk NOT perform in the process outlined?
Which task did Schenk NOT perform in the process outlined?
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What role did Schenk play in the original draft process?
What role did Schenk play in the original draft process?
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In the overall process described, which activity is primarily focused on refining the work?
In the overall process described, which activity is primarily focused on refining the work?
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Which of the following best describes formal analysis in this context?
Which of the following best describes formal analysis in this context?
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What is the primary function of data curation in Schenk's outlined process?
What is the primary function of data curation in Schenk's outlined process?
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Who is acknowledged for their assistance with the critical review of the manuscript?
Who is acknowledged for their assistance with the critical review of the manuscript?
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What type of assistance did Thomas Miller provide?
What type of assistance did Thomas Miller provide?
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In the acknowledgment section, the authors express gratitude specifically towards which individual?
In the acknowledgment section, the authors express gratitude specifically towards which individual?
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The authors' acknowledgment implies the importance of which aspect in manuscript preparation?
The authors' acknowledgment implies the importance of which aspect in manuscript preparation?
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The acknowledgment serves to highlight contributions from individuals who are not part of which group?
The acknowledgment serves to highlight contributions from individuals who are not part of which group?
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Study Notes
Canine Hypothyroidism and Corneal Lipidosis
- Hypothyroidism is the most common canine endocrinopathy, estimated at 0.2%-0.8% prevalence.
- It often results from primary acquired thyroiditis, but other types exist.
- Clinical signs include systemic and ocular manifestations, including keratoconjunctivitis sicca, arcus lipoides corneae, lipemic aqueous, ocular hemorrhage, lipemia retinalis, and bullous retinal detachment.
- Corneal lipidosis, specifically arcus lipoides corneae, involves lipid deposition in the cornea.
- Arcus lipoides corneae often manifests bilaterally and is associated with hypothyroidism in dogs.
Case Summary
- A 4-year-old spayed female Sheepdog-Poodle presented with visual impairment due to corneal opacification.
- The opacification and impairment had progressed over 2 years.
- Initial presentation showed bilateral, severe arcus lipoides corneae.
- Bilateral, symmetric, and multifocal bullous retinal detachments were noted.
- Hyperlipidemia (likely related to primary acquired thyroiditis) was detected.
- Unilateral lamellar keratectomy improved corneal clarity and visual function.
- Bilateral retinal detachment and hyperlipidemia resolved following thyroxine supplementation.
- Ocular symptoms improved, with the treated eye showing better clarity and the untreated eye remaining static.
Surgical Procedure
- Lamellar keratectomy was performed on the affected eye (OD).
- A 6400 Beaver blade was used to perform the circumferential lamellar keratectomy, avoiding ~1 mm from the limbus.
- The depth was less than 50% of total corneal thickness.
- A Martinez corneal dissector was used to continue the dissection.
- Some clear cornea was preserved centrally.
- Amnion membrane was applied to the cornea, secured with sutures, and covered with a bandage contact lens.
- Partial temporary tarsorrhaphy was done.
Post-Operative Care
- Topical and systemic medications were prescribed post-operatively, and systemic medication was continued with monitoring.
- Ofloxacin, tobramycin, and topical lubrication were administered.
- Carprofen and gabapentin were also given.
Histopathology
- Histopathological analysis of the excised cornea exhibited severe chronic granulomatous keratitis, stromal fibrosis, and cholesterol clefts.
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Description
Test your knowledge on the prevalence and complications of hypothyroidism in dogs, as well as common ocular abnormalities found in canines. This quiz covers surgical approaches and implications of various eye conditions. Challenge yourself to see how much you know about these important veterinary topics.
