Vestibulocerebellum Lesions

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Questions and Answers

Lesions to the cerebellum typically result in what type of motor deficit?

  • Inaccurate movements and motor errors. (correct)
  • Inability to initiate movements.
  • Complete paralysis of specific muscle groups.
  • Uncontrollable muscle spasms.

How does the cerebellum contribute to motor control?

  • By correcting motor errors through comparing intended and actual movements. (correct)
  • By directly initiating voluntary movements.
  • By relaying sensory information to the cerebral cortex.
  • By regulating muscle tone and reflexes.

What is the function of the "internal models" used by the cerebellum?

  • To generate emotional responses to movement.
  • To store memories of past motor actions.
  • To control autonomic functions during physical activity.
  • To provide a dynamic representation of the limbs and body. (correct)

How does the cerebellum update its internal models to improve motor performance?

<p>Through trial and error learning. (A)</p>
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What happens to smooth pursuit eye movements when there is a lesion in the left vestibulocerebellum when tracking a target moving from right to left?

<p>Smooth pursuit is interrupted by saccades. (D)</p>
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What is the vestibulo-ocular reflex (VOR)?

<p>A reflex that stabilizes vision during head movements. (D)</p>
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In a patient with normal responses to vestibular stimulation, what happens to their ability to fixate on an object during leftward head rotation if they have a lesion in the vestibulocerebellum?

<p>Fixation is disrupted. (B)</p>
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During prism adaptation, what is the role of the cerebellum?

<p>To update internal models and correct for the altered visual input. (A)</p>
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What is the likely outcome for a patient with focal olivocerebellar lesions when attempting prism adaptation?

<p>The patient will be unable to adapt and correct their movements. (B)</p>
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How does the cerebellum contribute to the accuracy of voluntary movements?

<p>Both A and B (C)</p>
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A patient with cerebellar damage is asked to perform a rapid alternating movement, such as pronating and supinating their hand. What is the likely presentation?

<p>The movement will be slow and irregular. (A)</p>
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Which of the following is NOT a primary function of the cerebellum?

<p>Initiation of voluntary movement (B)</p>
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A patient attempts to touch their nose with their finger, but their movement is hesitant, indirect, and characterized by oscillations around the intended trajectory. What is this called?

<p>Ataxia (C)</p>
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In the context of motor learning, what does the cerebellum contribute by using 'internal models'?

<p>All of the above. (D)</p>
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A person with cerebellar dysfunction might display which of the following characteristics when speaking?

<p>Scanning speech (slow with prolonged pauses) with unnatural inflection. (C)</p>
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You ask a patient to stand with their feet together and eyes closed, and they begin to sway and lose their balance. What is this most likely related to?

<p>Cerebellar ataxia. (B)</p>
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What is the primary role of the cerebellum in maintaining posture?

<p>Fine-tuning muscle tone and coordinating synergistic muscle groups. (A)</p>
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If a patient has difficulty judging distances and overshoots or undershoots when reaching for objects, which condition is most likely affecting them?

<p>Dysmetria (D)</p>
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Which of the following best describes the impact of cerebellar lesions on cognitive function?

<p>Cerebellar lesions can affect specific cognitive domains such as executive function, spatial cognition, and language. (D)</p>
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Why is it important to consider the cerebellum's function when designing rehabilitation strategies for individuals with motor impairments?

<p>To promote error-based learning and recalibration of motor programs. (A)</p>
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Flashcards

Cerebellum Lesions

Cerebellar lesions don't cause paralysis, but lead to errors in movement.

Cerebellum Role

Area of the brain responsible for correcting motor errors.

Internal Models

Internal representations of body mechanics used for movement.

Vestibulocerebellum Lesion Effect

Lesions affect tracking movements towards the side of the lesion.

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Study Notes

  • Lesions of the cerebellum do not paralyze movement, but result in large movement errors
  • The cerebellum plays a role in correcting "motor errors" by comparing the intended movement with the actual movement
  • The cerebellum contains "internal models" that represents a dynamic model of the limbs
  • Internal models are updated by trial and error

Vestibulocerebellum Lesions

  • Lesions in the vestibulocerebellum have large effects on smooth-pursuit eye movements
  • Sinusoidal target motion is tracked with smooth-pursuit eye movements as the target moves from left (L) to right (R)
  • Lesion of the left vestibulocerebellum causes smooth pursuit to be punctuated by saccades when the target moves from right to left
  • Patients with vestibulocerebellum lesions have normal responses to vestibular stimulation
  • Object fixation is disrupted during leftward rotation
  • Each trace shows the eye movements evoked by head rotation while the patient fixates on a target that moves along with him, first in the dark and then in the light
  • In the dark the eyes show a normal vestibulo-ocular reflex (VOR) during rotation in both directions: The eyes move smoothly in the direction opposite to the head's rotation, then reset with saccades in the direction of head rotation
  • In the light the eye position during rightward head rotation is normal: Fixation on the target is excellent and the vestibulo-ocular reflex is suppressed
  • During leftward head rotation, however, the subject is unable to fixate on the object and the vestibulo-ocular reflex cannot be suppressed

Prism Adaptation

  • Individuals adapt to prism glasses over time
  • Patients with lesions to the olivocerebellar area are unable to adapt to prism glasses and cannot hit the target

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