Vertebrate Limb Formation Quiz
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Questions and Answers

What is the primary role of Hox genes in the formation of the vertebrate limb?

  • Hox genes directly induce the expression of Tbx genes
  • Hox genes specify the anterior-posterior patterning of the limb
  • Hox genes regulate the expression of FGF10 and FGF8
  • Hox genes establish conditions for the synthesis of retinoic acid (correct)

    • Which of the following factors is responsible for specifying the type of limb that forms?

  • The anterior-posterior patterning of the limb field
  • The type of Tbx gene expressed (correct)
  • Retinoic acid
  • FGF10

    • What is the primary role of FGF in the initiation of limb bud formation?

  • FGF induces the expression of Hox genes
  • FGF directly induces the expression of Tbx genes
  • FGF can induce the formation of ectopic limbs (correct)
  • FGF specifies the anterior-posterior patterning of the limb

    • What is the role of retinoic acid in the initiation of limb bud formation?

    <p>Retinoic acid induces the transcription of Tbx genes</p> Signup and view all the answers

    Which of the following is a source of cells that contribute to limb bud development?

    <p>Somatic mesoderm</p> Signup and view all the answers

    What is the role of Wnt signaling in the initiation of limb bud formation?

    <p>Wnt signaling is required for the expression of FGF10 and FGF8</p> Signup and view all the answers

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