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Questions and Answers
What is the primary role of Hox genes in the formation of the vertebrate limb?
What is the primary role of Hox genes in the formation of the vertebrate limb?
- Hox genes directly induce the expression of Tbx genes
- Hox genes specify the anterior-posterior patterning of the limb
- Hox genes regulate the expression of FGF10 and FGF8
- Hox genes establish conditions for the synthesis of retinoic acid (correct)
Which of the following factors is responsible for specifying the type of limb that forms?
Which of the following factors is responsible for specifying the type of limb that forms?
- The anterior-posterior patterning of the limb field
- The type of Tbx gene expressed (correct)
- Retinoic acid
- FGF10
What is the primary role of FGF in the initiation of limb bud formation?
What is the primary role of FGF in the initiation of limb bud formation?
- FGF induces the expression of Hox genes
- FGF directly induces the expression of Tbx genes
- FGF can induce the formation of ectopic limbs (correct)
- FGF specifies the anterior-posterior patterning of the limb
What is the role of retinoic acid in the initiation of limb bud formation?
What is the role of retinoic acid in the initiation of limb bud formation?
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Which of the following is a source of cells that contribute to limb bud development?
Which of the following is a source of cells that contribute to limb bud development?
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What is the role of Wnt signaling in the initiation of limb bud formation?
What is the role of Wnt signaling in the initiation of limb bud formation?
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