6 Questions
What is the primary role of Hox genes in the formation of the vertebrate limb?
Hox genes establish conditions for the synthesis of retinoic acid
Which of the following factors is responsible for specifying the type of limb that forms?
The type of Tbx gene expressed
What is the primary role of FGF in the initiation of limb bud formation?
FGF can induce the formation of ectopic limbs
What is the role of retinoic acid in the initiation of limb bud formation?
Retinoic acid induces the transcription of Tbx genes
Which of the following is a source of cells that contribute to limb bud development?
Somatic mesoderm
What is the role of Wnt signaling in the initiation of limb bud formation?
Wnt signaling is required for the expression of FGF10 and FGF8
Test your knowledge on the formation of vertebrate limbs, including the patterning of the proximal/distal and anterior/posterior axis, initiation of limb outgrowth, limb field specification, and limb bud development.
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