Varicose Veins and Their Etiology

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Questions and Answers

What does the Trendelenburg test II indicate if filling of blood from below upwards is observed within 30-60 seconds?

  • Normal perforator function
  • Superficial vein thrombosis
  • Deep vein thrombosis
  • Perforator incompetence (correct)

The Modified Perthes' test is used to confirm the presence of deep vein thrombosis.

True (A)

What does the Schwartz test assess in a vein?

Incompetent valves between the segments of the vein

Fegan's test involves marking the site where the perforators enter the deep fascia and observing a __________ on lying down.

<p>button-like depression</p> Signup and view all the answers

Match the following tests with their purposes:

<p>Trendelenburg test II = Assess perforator incompetence Multiple tourniquet test = Determine exact site of perforators Schwartz test = Check for superficial column of blood Modified Perthes' test = Rule out deep vein thrombosis</p> Signup and view all the answers

What is one key symptom that patients with dilated veins in the leg may experience?

<p>Swelling of the legs (B)</p> Signup and view all the answers

Night cramps in patients with dilated veins occur due to narrowing of veins.

<p>False (B)</p> Signup and view all the answers

What type of pain is commonly associated with dilated veins in the legs?

<p>Dull aching pain</p> Signup and view all the answers

Increased _______ pressure can lead to swelling in the legs.

<p>hydrostatic</p> Signup and view all the answers

Match the symptoms to their descriptions:

<p>Swelling of the legs = Increased interstitial fluid accumulation Dull aching pain = Heaviness in the limb Night cramps = Change in diameter of veins Ulcers = Prevention of nutrients reaching the muscles</p> Signup and view all the answers

What condition can occur due to pooling of deoxygenated blood in the limbs?

<p>Ulcers (C)</p> Signup and view all the answers

Patients with increased hydrostatic pressure may experience bleeding.

<p>True (A)</p> Signup and view all the answers

What factors contribute to the swelling of the legs in patients?

<p>Increased volume of fluid, impaired lymphatic drainage, increased hydrostatic pressure</p> Signup and view all the answers

What is one reason for examining the abdomen in relation to varicose veins?

<p>To locate pelvic tumours and lymph nodes (D)</p> Signup and view all the answers

Ultrasound of the abdomen is one of the investigations that can be conducted to evaluate varicose veins.

<p>True (A)</p> Signup and view all the answers

What types of tests may be performed to investigate the cause of varicose veins?

<p>Ultrasound abdomen, peripheral smear, platelet count</p> Signup and view all the answers

One potential complication of lymph node compression over veins is _____ in the legs.

<p>varicosity</p> Signup and view all the answers

Match the investigation with its purpose:

<p>Ultrasound abdomen = Visualize pelvic tumours or abnormalities Peripheral smear = Assess blood cell counts Platelet count = Determine clotting ability MRI = Detailed imaging of soft tissues</p> Signup and view all the answers

What is the primary characteristic of varicose veins?

<p>Permanently elongated and dilated veins (C)</p> Signup and view all the answers

Chronic constipation is a risk factor for developing varicose veins.

<p>True (A)</p> Signup and view all the answers

Name one risk factor associated with the development of varicose veins.

<p>female sex</p> Signup and view all the answers

The CEAP classification for varicose veins ranges from ___ to ___.

<p>0 to 6</p> Signup and view all the answers

Which of the following is part of the etiology of varicose veins?

<p>Raised estrogen-progesterone ratio (D)</p> Signup and view all the answers

Match the risk factors for varicose veins with their descriptions:

<p>Heredity = Genetic predisposition to venous issues Prolonged standing = Occupation-related stress on veins High heels = Footwear that increases leg strain Pregnancy = Hormonal changes and increased belly pressure</p> Signup and view all the answers

What is the primary issue with the valves in varicose veins?

<p>Faulty valves cause reversal of blood flow.</p> Signup and view all the answers

The white cell trapping theory suggests that trapped leucocytes activate and cause cell destruction in varicose veins.

<p>True (A)</p> Signup and view all the answers

What condition is suggested by sudden pain in the calf region with fever and oedema?

<p>Deep vein thrombosis (DVT) (C)</p> Signup and view all the answers

Ankle flare is characterized by the presence of reticular veins near the lateral malleolus.

<p>False (B)</p> Signup and view all the answers

What does a single dilated varix at the saphena junction indicate?

<p>Saphena varix</p> Signup and view all the answers

The _____ test indicates saphenofemoral incompetence through a fluid thrill felt at the SF junction.

<p>Cough impulse</p> Signup and view all the answers

Match the signs and tests with their respective descriptions:

<p>Visible dilated veins = A sign of venous insufficiency Brodie-Trendelenburg test = Tests for saphenofemoral incompetence Ankle flare = Reticular veins near the medial malleolus Saphena varix = Dilated varix at the saphena junction</p> Signup and view all the answers

Which of the following symptoms may result from complications of DVT?

<p>Ulceration (A)</p> Signup and view all the answers

The Brodie-Trendelenburg test involves elevating the limb and tying a tourniquet below the sapheno-femoral junction.

<p>True (A)</p> Signup and view all the answers

What skin changes may occur due to venous insufficiency?

<p>Eczema and dermatitis</p> Signup and view all the answers

Flashcards

What are varicose veins?

Varicose veins are permanently enlarged and twisted veins where blood flow is reversed due to faulty valves.

How does raised intra-abdominal pressure contribute to varicose veins?

Increased pressure in the abdomen, often caused by factors like pregnancy, obesity, or tight clothing.

Explain the white cell trapping theory for varicose vein pathogenesis.

The white blood cells get trapped in enlarged veins, leading to inflammation and damage.

What are some common risk factors for varicose veins?

Heredity (family history), female sex, prolonged standing, immobility, pregnancy, and certain medications.

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Where is the saphenofemoral junction located?

The saphenofemoral junction is the point where the great saphenous vein joins the femoral vein. It's located about 4 cm below the lateral tubercle and medial to the pubic tubercle.

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What is the CEAP classification?

The CEAP classification helps categorize varicose veins based on their clinical appearance, etiology, anatomy, and pathophysiology.

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How do hormonal changes influence varicose veins?

Elevated levels of progesterone and altered estrogen-progesterone ratio, particularly during pregnancy.

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What are the consequences of varicose veins?

They are enlarged, twisted veins that can cause pain, swelling, and skin problems.

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Deep Vein Thrombosis (DVT)

A condition where a blood clot forms in a deep vein, often in the legs. It can be caused by prolonged inactivity, injury, or certain medical conditions.

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Varicose Veins

A bulging, dilated vein, often found in the legs. It occurs when the valves in the vein become weak and allow blood to pool.

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Saphena Varix

A saccular dilatation of the upper end of the long saphenous vein at the saphenous opening.

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Cough Impulse Test (Morrissey's Test)

A test where the doctor keeps a finger on the saphenofemoral junction and asks the patient to cough. A fluid thrill, an impulse felt by the fingers, is indicative of ‘saphenofemoral incompetence’.

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Brodie-Trendelenburg Test

The vein is emptied by elevating the limb and a tourniquet is tied just below the sapheno-femoral junction. Patient is asked to stand quickly. When the tourniquet is released, rapid filling from above signifies saphenofemoral incompetence.

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Ankle Flare

A group of reticular veins near the medial malleolus. Complications such as ulceration, bleeding, eczema, and dermatitis may be present. Pigmentation is often seen.

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Blowout

A localised, dilated segment of the vein, often indicating an underlying perforator vein.

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Venous Incompetence

A condition where the valves in the veins are not working properly, causing blood to flow backwards and pool in the legs. Symptoms can include swelling, pain, and fatigue.

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Why is an abdominal exam important for varicose veins?

The abdominal examination may reveal enlarged lymph nodes, which could be pressing on nearby veins and contributing to varicose veins.

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What is an ultrasound used for?

Ultrasound of the abdomen can help identify problems with veins and blood flow in the legs, which can be related to varicose veins.

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Why is a peripheral smear done?

A peripheral blood smear is a test used to examine blood cells under a microscope, which can help identify potential problems like inflammation that may be contributing to varicose veins.

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What is the purpose of a platelet count?

Platelet count measures the number of platelets in the blood, which are crucial for blood clotting and wound healing. If platelet count is low, it can increase the risk of prolonged bleeding, which might worsen varicose veins.

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Trendelenburg Test II

A test used to identify incompetent perforator veins. Involves applying a tourniquet to a leg, observing blood filling from below upwards, and assessing the time taken for filling.

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Multiple Tourniquet Test

A procedure to pinpoint the exact location of perforator veins. Multiple tourniquets are applied to different leg sections, and blood flow is observed.

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Schwartz Test

Used to assess the competency of valves between segments of a superficial vein. It involves palpating a dilated vein segment and tapping it, resulting in a palpable impulse if valves are inadequate.

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Modified Perthes' Test

A test to exclude deep vein thrombosis. It involves applying a tourniquet at the saphenofemoral junction, walking, and observing for pain and swelling. These symptoms suggest a potential DVT.

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Fegan's Test

A method to identify perforator sites in the leg. It involves marking the bulges at perforator locations while standing and then observing depressions at these points in the reclining position.

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Dilated Veins

Enlarged or swollen veins in the leg, often visible on the surface of the skin. This is a common symptom of venous insufficiency.

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Leg Swelling

Swelling in the legs, usually caused by the accumulation of fluid in the tissues due to poor blood circulation.

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Dragging Pain

A dull, aching pain, often described as a feeling of heaviness, usually in the legs. It's often worse in the evening and relieved by elevating the legs.

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Night Cramps

Sharp, sudden pain in the legs, often occurring at night. These cramps are caused by changes in the diameter of the veins.

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Ulcers and Eczema

Ulcers are open sores or wounds, while eczema is a skin condition that causes inflammation, itching, and dryness. Both can occur in venous insufficiency due to poor blood flow and oxygen supply to the area.

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Bleeding

Bleeding, often from the affected area, can occur in venous insufficiency. It's often due to the weakening of blood vessel walls.

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What is Venous Insufficiency?

Venous insufficiency is a condition where the veins in the legs don't work properly, causing blood to pool in the legs instead of flowing back to the heart.

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Evening Worsening

The symptoms of venous insufficiency are often worse in the evening, as blood tends to pool in the legs throughout the day when standing or sitting for long periods.

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Study Notes

Varicose Veins

  • Varicose veins are dilated, elongated veins with a tortuous path, causing abnormal blood flow.
  • Risk factors include heredity, female sex, prolonged standing, immobility, increased intra-abdominal pressure (e.g., pregnancy, sports), tight clothing, high heels, and altered estrogen/progesterone ratios.

Etiology of Varicose Veins

  • Varicose veins are more common in the lower limbs due to upright posture and the need to support a column of blood.
  • Primary varicose veins are due to:
  • Congenital valve incompetence.
  • Weakness or wasting of muscles and connective tissues in the vein walls.
  • Stretching of the deep fascia.
  • Inherited factors (e.g., FOXC2 gene mutations).
  • Conditions like Klippel-Trenaunay syndrome, avalvulia, and Parkes-Weber syndrome.
  • Secondary varicose veins are due to:
  • Recurrent thrombophlebitis.
  • Prolonged standing, like in certain occupations.
  • Obstructions to venous return (tumours, fibrosis, etc).
  • Pregnancy.
  • Obesity.
  • Chronic constipation.
  • Valve incompetence.

Pathogenesis of Varicose Veins

  • White cell trapping theory: inappropriate leucocyte activation leads to proteolytic enzyme release, cell destruction, and ulceration.
  • Incompetent venous valves lead to blood pooling and chronic ambulatory venous hypertension.
  • Red blood cell lysis leads to haemoglobin breakdown and pigment release (haemosiderin).
  • This contributes to pigmentation, inflammation, and subsequent dermatitis.
  • Chronic venous ulceration can occur due to a combination of factors.

Clinical Features and Symptoms

  • Most patients present with dilated veins, swelling, dull aching pain (relieved by elevation), and heaviness in the legs.
  • Impaired lymphatic drainage, increased interstitial fluid, and increased hydrostatic pressure contribute to swelling.
  • Night cramps may occur due to changes in vein diameter and restriction of nutrient/oxygen supply to muscles.
  • Sudden calf pain, swelling, fever, ankle oedema (deep vein thrombosis), pruritus (itching), and skin thickening are also common indicators.
  • Bleeding, dermatitis, and ulceration are possible complications.

Diagnostic Tests and Investigations

  • Cough impulse test (Morrissey's test): Fluid thrill felt with cough indicates saphenofemoral incompetence.

  • Brodie-Trendelenburg test: Rapid filling from above indicates saphenofemoral incompetence; delayed filling from below indicates perforator incompetence.

  • Multiple tourniquet test: Used to determine perforator competency by observing vein filling.

  • Schwartz test: Palpable impulse in dilated veins with incompetent valves between them.

  • Modified Perthes' test for deep vein thrombosis (DVT) assessment.

  • Doppler Ultrasound: Detects blood flow and detects incompetent valves.

  • Venography and Plethysmography: Used less often now due to better diagnostic technologies.

  • Complete physical examination: Examination of the abdomen for tumour & lymph nodes is crucial because they can interfere with the flow pathways.

  • Examination of the leg helps to assess specific details such as location and size of the dilated veins and the presence of associated skin changes.

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