25 Questions
What is the primary mode of CMV infection?
Direct contact with bodily fluids
Which drug is a DNA polymerase inhibitor used in the treatment of CMV infection?
Cidofovir
In which patient population is Maribavir specifically used for resistant CMV?
Renal patients
Which organ transplantation procedure is most affected by CMV reactivation?
Kidney transplantation
What is the hallmark of CMV infection histologically known as?
"Owl eyes" inclusion bodies
Which virus is associated with Burkitt lymphoma in immunocompromised individuals primarily outside the U.S.?
Epstein-Barr Virus (EBV)
What is the most common mode of transmission for Epstein-Barr Virus (EBV)?
Saliva
Which virus causes over 90% of cases of infectious mononucleosis, also known as the 'kissing disease'?
Epstein-Barr Virus (EBV)
Which of the following is NOT a symptom associated with Epstein-Barr Virus (EBV) infection?
Pneumonia
Which virus is commonly treated with Ganciclovir or Valganciclovir?
Cytomegalovirus (CMV)
Which virus is the main focus of treatment with Ganciclovir/Valganciclovir?
Cytomegalovirus (CMV)
Which infection is commonly associated with symptoms like postherpetic neuralgia?
Shingles
In case of resistance to acyclovir in HSV infections, which drug is used as an alternative (though nephrotoxic)?
Foscarnet
Which drug is known for causing nephrotoxicity and is primarily used in the treatment of CMV infections?
Foscarnet
Which antiviral drug is known for inhibiting viral DNA polymerase to stop DNA synthesis in the treatment of various herpes infections?
Acyclovir
What is the recommended treatment for Cytomegalovirus (CMV) infection in immunocompromised patients?
Valganciclovir
Which of the following is a potential side effect of Ganciclovir therapy for CMV infection?
Peripheral neuropathy
What is the primary mode of transmission of Epstein-Barr Virus (EBV)?
Respiratory droplets
Which of the following antiviral drugs is a pyrophosphate analog used in the treatment of Cytomegalovirus (CMV) retinitis?
Foscarnet
In which patient population is Maribavir primarily indicated for the treatment of CMV infection?
Immunocompromised patients
Which treatment for CMV works by inhibiting viral DNA polymerase and causing termination of DNA elongation?
Foscarnet
What is the mechanism of action of Ganciclovir/Valganciclovir in treating CMV?
Selective inhibition of CMV replication by DNA incorporation
What is a potential side effect of Foscarnet used in CMV treatment?
Nephrotoxicity
Which medication used for CMV treatment can lead to the development of retinitis as a side effect?
Cidofovir
Which CMV treatment is known for its mechanism of action involving inhibition of the viral terminase complex?
Maribavir
Test your knowledge about Varicella Zoster Virus (VZV), also known as HSV3. Explore its transmission, primary infection sites, latency in neurons, and the relationship between chickenpox and shingles.
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