Antidiuretic Agonists Antagonists

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Questions and Answers

Which of the following is a common adverse effect of antidiuretic antagonists?

  • Dry mouth (correct)
  • Decreased urination
  • Weight gain
  • Fluid retention

What is the primary action of antidiuretic antagonists on water reabsorption?

  • Increases water reabsorption in kidneys
  • Decreases water reabsorption in kidneys (correct)
  • Increases sodium retention
  • No effect on water reabsorption

Which of the following is a caution associated with the use of antidiuretic antagonists?

  • Lower blood pressure
  • Possible severe dehydration in fluid-restricted patients (correct)
  • Reduced thirst
  • Increased risk of edema

What is the effect of antidiuretic antagonists on urine formation?

<p>Increased urine formation (C)</p> Signup and view all the answers

Which of the following is a listed adverse effect of antidiuretic antagonists?

<p>Dry skin (B)</p> Signup and view all the answers

What is the effect of antidiuretic antagonists on sodium concentration in the blood?

<p>Decreases sodium concentration (A)</p> Signup and view all the answers

Which of the following is a caution related to antidiuretic antagonists?

<p>May cause severe dehydration (C)</p> Signup and view all the answers

Which of the following is the generic name for Neph-Tolvaptan?

<p>Tolvaptan (A)</p> Signup and view all the answers

Which of the following is an antidiuretic antagonists?

<p>Tolvaptan (B)</p> Signup and view all the answers

Flashcards

Antidiuretic Antagonists

Antidiuretic antagonists decrease water reabsorption in the kidneys. They promote urine formation and decrease sodium concentration in the blood.

Vaptan Drugs

Tolvaptan and Conivaptan

Adverse Effects of -Vaptans

Dry mouth, dry skin, frequent urination, and severe liver damage.

Cautions with -Vaptans

Patients with restricted fluid intake can become severely dehydrated

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Study Notes

  • Antidiuretic agonists are antagonists
  • These agents decrease water reabsorption in the kidneys, promoting urine formation and decreasing sodium concentration in the blood.
  • The drug class name is Vaptans

Drug names

  • Tolvaptan
  • Conivaptan
  • Tolvaptan Tablets are available in 15mg

Adverse effects

  • Dry mouth
  • Dry skin
  • Frequent urination
  • Severe liver damage

Cautions

  • Fluid-restricted patients can become severely dehydrated.

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