Vaginal Squamous Cell Carcinoma in Female Reproductive System

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What is the typical age range for women to experience breast fibrocystic changes?

50-70 years

Over 70 years

25-50 years (correct)

15-25 years

Which protein is the immature teratoma component positive for?

Glial fibrillary acidic protein (GFAP) (correct)

Estrogen receptor

Progesterone receptor

Androgen receptor

What is the main cause of gynecomastia in elderly men?

Puberty

Chemotherapy

Endogenous hormonal imbalance (correct)

Liver failure

What type of cells typically line type 1 breast cysts in fibrocystic changes?

Metaplastic apocrine cells Signup and view all the answers

What is the microscopic feature of 'florid type' gynecomastia?

Increased ducts with cellular periductal stroma Signup and view all the answers

What is the defining feature of adenososis?

Increased ductules and lobular expansion with epithelial proliferation Signup and view all the answers

Which histologic type is the most common in primary vaginal squamous cell carcinoma?

Usual nonkeratinizing Signup and view all the answers

What defines a primary vaginal squamous cell carcinoma?

No history of invasive SCC of the cervix or vulva diagnosed for at least 10 years Signup and view all the answers

What are the three independent prognostic factors for primary vaginal squamous cell carcinoma?

Old age, tumor size >4 cm, advanced stage Signup and view all the answers

Where does sarcoma botryoides (embryonal rhabdomyosarcoma) most commonly occur in the female genital tract?

Vagina Signup and view all the answers

At what age group does sarcoma botryoides (embryonal rhabdomyosarcoma) typically occur?

Young girls less than 10 years of age Signup and view all the answers

How does sarcoma botryoides (embryonal rhabdomyosarcoma) typically present?

With a characteristic appearance of a 'bunch of grapes' Signup and view all the answers

What is the size threshold that differentiates a benign serous tumor from a cortical inclusion cyst?

1 cm Signup and view all the answers

In what percentage of cases are benign serous tumors bilateral?

20% Signup and view all the answers

What may be apparent in the cyst wall of benign serous tumors that does not necessarily indicate low malignant potential?

Nodularity/papillary structures Signup and view all the answers

Which type of epithelium lines serous cystadenomas?

Flat epithelium Signup and view all the answers

What differentiates serous cystadenomas from serous cystadenofibromas regarding architecture?

Presence of broad fibrous stromal cores Signup and view all the answers

What term is used to describe foci of epithelial changes in serous cystadenomas involving less than 10% of the neoplasm?

Serous cystadenoma with focal epithelial proliferation Signup and view all the answers

What is a characteristic feature of infiltrating lobular carcinoma that makes it difficult to detect on mammography?

Permeative growth pattern Signup and view all the answers

Which type of breast carcinoma has a predilection for metastasizing to viscera, bone marrow, and meninges?

Lobular carcinoma Signup and view all the answers

What is a common histologic feature of the classic form of infiltrating lobular carcinoma?

Desmoplastic stroma with basophilic appearance Signup and view all the answers

Which age group is more commonly affected by carcinoma of the male breast compared to women?

60+ years Signup and view all the answers

What type of breast carcinoma may have both clinically inflammatory features without lymphatic plugging?

Inflammatory carcinoma Signup and view all the answers

What is a distinguishing feature of lobular neoplasia in infiltrating lobular carcinoma cases?

Often arranged in targetoid patterns around ducts Signup and view all the answers

Which type of endometrial carcinoma is typically high-grade and has early dissemination to the pelvis and abdomen?

Serous carcinoma Signup and view all the answers

What is the most common uterine neoplasm, typically presenting with symptoms like pain, pressure sensation, and abnormal uterine bleeding?

Leiomyoma Signup and view all the answers

In serous carcinoma, what factor has been reported to be over-expressed and/or amplified in a significant proportion of cases, suggesting it may be a therapeutic target?

HER2 Signup and view all the answers

Which type of carcinoma is characterized by a papillary pattern with broad fibrovascular cores, high-grade nuclei, and frequent mitotic figures along with necrotic foci?