6 Questions
Which physiological abnormalities are associated with beta thalassemia major?
Iron overload, oxidative stress, and aggregated β-globin proteins
What is the main role of acetylcholinesterase (AChE) in RBCs of beta thalassemia patients?
Participating in reactive oxygen species (ROS) production
Which membrane bound proteins show increased contents in RBCs of beta thalassemia patients?
Cyclooxygenase-2 (COX-2) and CD38
Which factor is implicated in the upregulation of cyclooxygenase-2 (COX-2) and CD38 in RBCs of beta thalassemia patients?
Iron overload
What is the main cause of oxidative stress in beta thalassemia major?
Iron overload and increased amyloid β (Aβ) peptides
Which process is induced by the overproduction of amyloid β (Aβ) peptides in RBCs?
Cell death, named eryptosis
Explore the physiological abnormalities and processes related to β thalassemia major through this study. Understand the possible changes facilitating eryptosis and death process in RBCs of patients with β thalassemia major.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
