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Questions and Answers
Which physiological abnormalities are associated with beta thalassemia major?
Which physiological abnormalities are associated with beta thalassemia major?
- High calcium levels, reduced oxidative stress, and abnormal hemoglobin structure
- Iron overload, oxidative stress, and aggregated β-globin proteins (correct)
- Low iron levels, reduced oxidative stress, and aggregated α-globin proteins
- High cholesterol levels, increased oxidative stress, and abnormal RBC size
What is the main role of acetylcholinesterase (AChE) in RBCs of beta thalassemia patients?
What is the main role of acetylcholinesterase (AChE) in RBCs of beta thalassemia patients?
- Producing amyloid β (Aβ) peptides
- Regulating calcium levels
- Participating in reactive oxygen species (ROS) production (correct)
- Preventing inflammatory stress
Which membrane bound proteins show increased contents in RBCs of beta thalassemia patients?
Which membrane bound proteins show increased contents in RBCs of beta thalassemia patients?
- ATP synthase and cytochrome c
- Hemoglobin and myoglobin
- Glutathione peroxidase and catalase
- Cyclooxygenase-2 (COX-2) and CD38 (correct)
Which factor is implicated in the upregulation of cyclooxygenase-2 (COX-2) and CD38 in RBCs of beta thalassemia patients?
Which factor is implicated in the upregulation of cyclooxygenase-2 (COX-2) and CD38 in RBCs of beta thalassemia patients?
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What is the main cause of oxidative stress in beta thalassemia major?
What is the main cause of oxidative stress in beta thalassemia major?
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Which process is induced by the overproduction of amyloid β (Aβ) peptides in RBCs?
Which process is induced by the overproduction of amyloid β (Aβ) peptides in RBCs?
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