Sample Quiz

Summarize this

Silent Mutation 

A nucleotide change occurs at the DNA level but does not result in a structural change to the protein. 

Conservative Missense 

A single base change substitutes one amino acid for another with similar chemical properties (e.g., serine to threonine). 

Non-Conservative Missense 

A single base change substitutes one amino acid for another with different chemical properties, altering the protein’s function. 

Nonsense 

A single nucleotide change converts an amino acid codon into a STOP codon, halting protein synthesis prematurely. 

Frameshift 

Addition or deletion of nucleotides shifts the reading frame, altering the downstream amino acid sequence. 

Substitution (Transition/Transversion) 

Transition: Purine to purine or pyrimidine to pyrimidine. Transversion: Purine to pyrimidine or vice versa.