USMLE Review Part I
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Questions and Answers

What is the appropriate vaccination schedule for a non-pregnant, non-immunocompromised person aged 2 months?

  • HPV, Pneumo PCV13, Polio Salk
  • HepB, Polio Salk, Pneumo PCV13, DPT, HiB, rotavirus (correct)
  • MMR, Varicella, DPT, HepB
  • Pneumo PCV13, PPSV23, HiB
  • At what age should the second dose of the MMR vaccine be administered?

  • 6-14 months
  • 12-15 months
  • 2 years
  • 4-6 years (correct)
  • Which condition is characterized by a circular lesion in the pancreas associated with pancreatitis?

  • Pseudoabscess (correct)
  • Pseudocyst
  • Pancreatic cancer
  • Abscess
  • Which of the following lung issues is associated with centri-acinar emphysema?

    <p>Smokers</p> Signup and view all the answers

    What is true about FEV1/FVC ratios in restrictive lung disease?

    <p>Normal or increased FEV1/FVC</p> Signup and view all the answers

    What is the most common cause of otitis media?

    <p>Streptococcus pneumoniae</p> Signup and view all the answers

    What treatment is recommended for recurrent otitis media?

    <p>Amoxicillin/clavulanate</p> Signup and view all the answers

    What is the initial treatment approach for rheumatoid arthritis?

    <p>Symptom-relief and DMARDs</p> Signup and view all the answers

    Which of the following treatments is appropriate for otitis externa?

    <p>Topical ciprofloxacin + hydrocortisone drops</p> Signup and view all the answers

    What type of joint involvement is characteristic of osteoarthritis compared to rheumatoid arthritis?

    <p>Only DIPs involved</p> Signup and view all the answers

    What laboratory findings indicate iron deficiency anemia?

    <p>Low hematocrit, low MCV, low iron, low ferritin</p> Signup and view all the answers

    What is the mechanism of action of methotrexate?

    <p>Inhibits dihydrofolate reductase</p> Signup and view all the answers

    In a patient with anemia of chronic disease, what is the treatment if the cause is renal failure?

    <p>Erythropoietin (EPO)</p> Signup and view all the answers

    What is the best approach for reducing stroke risk in a hypertensive smoker with a history of TIA?

    <p>Lisinopril</p> Signup and view all the answers

    Which of the following patients is most likely to develop septic arthritis?

    <p>A person with prosthetic joint implants</p> Signup and view all the answers

    What is the diagnosis method for thalassemia?

    <p>Hemoglobin electrophoresis</p> Signup and view all the answers

    What are the common side effects associated with methotrexate?

    <p>Pulmonary fibrosis and hepatotoxicity</p> Signup and view all the answers

    What is the most common finding in systemic lupus erythematosus (SLE)?

    <p>Arthritis</p> Signup and view all the answers

    Which finding is associated with thalassemia rather than iron deficiency anemia?

    <p>Low hematocrit + normal MCV + normal iron + normal ferritin</p> Signup and view all the answers

    Which drug is considered the first-line disease-modifying anti-rheumatic drug (DMARD) for early rheumatoid arthritis?

    <p>Methotrexate</p> Signup and view all the answers

    In patients with osteoarthritis taking NSAIDs, what causes the peripheral edema?

    <p>Increased sodium retention due to decreased renal blood flow</p> Signup and view all the answers

    What is the most specific antibody for Systemic Lupus Erythematosus (SLE)?

    <p>anti-Smith</p> Signup and view all the answers

    Which histological pattern is characteristic of diffuse proliferative glomerulonephritis (DPGN) in lupus nephritis?

    <p>Wire looping capillary pattern</p> Signup and view all the answers

    What is the initial treatment for an immune thrombocytopenic purpura (ITP) episode?

    <p>Steroids</p> Signup and view all the answers

    In a patient with bleeding, which finding is indicative of a platelet problem?

    <p>Increased bleeding time</p> Signup and view all the answers

    Which of the following drugs is associated with drug-induced lupus?

    <p>Hydralazine</p> Signup and view all the answers

    What is the mechanism of immune thrombocytopenic purpura (ITP)?

    <p>Antibodies against platelets</p> Signup and view all the answers

    What is the classic presentation of hemophilia in a child?

    <p>Hemarthrosis</p> Signup and view all the answers

    What is the next best step in diagnosis for viral-induced aplastic anemia?

    <p>Bone marrow aspiration</p> Signup and view all the answers

    What is the secondary function of von Willebrand factor (vWF)?

    <p>Stabilizes factor VIII in plasma</p> Signup and view all the answers

    Which symptoms are indicative of a platelet problem in von Willebrand disease (vWD)?

    <p>Epistaxis, bruising, and petechiae</p> Signup and view all the answers

    What is the main cause of vitamin K deficiency in adults?

    <p>Chronic antibiotic use</p> Signup and view all the answers

    What mutation leads to sickle cell disease?

    <p>Glutamic acid to valine on beta-chain</p> Signup and view all the answers

    What is a common presentation of agranulocytosis in patients?

    <p>Mouth ulcers and fever</p> Signup and view all the answers

    Which antibiotics are examples of broad-spectrum agents used for febrile neutropenia?

    <p>Piperacillin/tazobactam; cefepime + vancomycin</p> Signup and view all the answers

    What is the strongest indication for anticoagulation therapy?

    <p>Prosthetic material in heart / prosthetic valve</p> Signup and view all the answers

    What is an appropriate use for ganciclovir?

    <p>Treatment of CMV infections</p> Signup and view all the answers

    Which organism is associated with bloody diarrhea after poultry consumption?

    <p>Campylobacter jejuni</p> Signup and view all the answers

    What is the first-line treatment for Clostridium difficile infection?

    <p>Vancomycin</p> Signup and view all the answers

    In a patient with community-acquired pneumonia presenting with bilateral infiltrates on chest X-ray, which organism is most likely implicated?

    <p>Mycoplasma pneumoniae</p> Signup and view all the answers

    What is the characteristic triad of symptoms indicating cardiac tamponade?

    <p>Hypotension + muffled heart sounds + JVD</p> Signup and view all the answers

    What is the most appropriate screening method for pulmonary embolism in a pregnant patient?

    <p>V/Q scan</p> Signup and view all the answers

    Which of the following acid-base disturbances is expected in a patient with pulmonary embolism?

    <p>Respiratory alkalosis</p> Signup and view all the answers

    Which organism is typically responsible for pneumonia in patients with exposure to rabbits?

    <p>Francisella tularensis</p> Signup and view all the answers

    When treating a pulmonary embolism in a patient who is already on warfarin, what is the next step?

    <p>Perform a spiral CT to confirm the diagnosis</p> Signup and view all the answers

    Study Notes

    USMLE Review Part I

    • This is a review guide for the USMLE Part I exam.
    • The document includes information on various medical topics.
    • It covers travel-related illnesses, diarrhea-causing pathogens, and their respective treatments.
    • It details other digestive issues and their diagnoses.
    • The document includes information relevant to cardiac conditions, like ischemia and pericarditis.
    • It provides details about diagnosing and managing conditions like cardiac ischemia, pericarditis, and ECG interpretation.
    • It includes information regarding various types of pneumonia and appropriate treatments.
    • The review covers diagnoses for various types of incontinence, with specific treatments for each.
    • The content is focused on the diagnosis and treatment of various medical conditions in a clinical context related to the USMLE Part I exam.

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    HY USMLE Review Part I PDF

    Description

    Prepare for the USMLE Part I exam with this comprehensive review guide. Covering critical medical topics such as travel-related illnesses, cardiac conditions, and pneumonia, this resource equips you with essential knowledge on diagnoses and treatments. Perfect for anyone looking to excel in the exam and strengthen their clinical understanding.

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