Ch 25, L4

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Questions and Answers

What is the primary function of tubular reabsorption in the kidneys?

  • To produce urine
  • To return essential substances to the bloodstream (correct)
  • To remove waste products from the blood
  • To filter blood cells and proteins

In what part of the kidney does tubular reabsorption primarily occur?

  • Glomerulus
  • Renal tubule (correct)
  • Bowman's capsule
  • Renal pelvis

What type of substances are almost entirely reabsorbed in the tubules?

  • Inorganic salts
  • Toxins
  • Metabolic wastes
  • Organic nutrients (correct)

Which process describes the movement of substances from the peritubular capillaries into the renal tubule?

<p>Secretion (B)</p> Signup and view all the answers

What is the role of antidiuretic hormone (ADH) in water reabsorption?

<p>Increases water reabsorption (B)</p> Signup and view all the answers

Which hormone regulates sodium reabsorption by the distal tubule and collecting duct?

<p>Aldosterone (A)</p> Signup and view all the answers

What is the driving force for the reabsorption of water in the proximal tubule?

<p>Osmosis due to solute concentration gradients (C)</p> Signup and view all the answers

Which ion's reabsorption is primarily controlled by parathyroid hormone (PTH)?

<p>Calcium (A)</p> Signup and view all the answers

Where does the majority of obligatory water reabsorption occur?

<p>Proximal tubule (A)</p> Signup and view all the answers

What is the impact of atrial natriuretic peptide (ANP) on sodium reabsorption in the kidneys?

<p>Decreases sodium reabsorption (B)</p> Signup and view all the answers

In the kidneys, what is meant by the term 'tubular secretion'?

<p>The movement of substances from the blood into the nephron tubule (C)</p> Signup and view all the answers

Which of the following is NOT typically reabsorbed in the tubules?

<p>Creatinine (D)</p> Signup and view all the answers

What type of transport requires energy (ATP) for reabsorption in the kidney tubules?

<p>Active transport (B)</p> Signup and view all the answers

Regarding water reabsorption, what is the role of aquaporins?

<p>They are channels that facilitate water movement (C)</p> Signup and view all the answers

What percentage of filtrate volume is typically reabsorbed?

<p>99% (B)</p> Signup and view all the answers

If blood pH is too acidic, what will the kidney tubules secrete?

<p>Hydrogen ions (B)</p> Signup and view all the answers

In which part of the nephron is the filtrate's osmolarity highest?

<p>Descending limb of the loop of Henle (A)</p> Signup and view all the answers

How does aldosterone affect potassium levels in the body?

<p>Increases potassium secretion (A)</p> Signup and view all the answers

What is the primary role of the sodium-potassium pump in tubular reabsorption?

<p>To establish a sodium gradient (D)</p> Signup and view all the answers

If a patient has high blood pressure, which hormone would the body likely release to reduce sodium reabsorption?

<p>Atrial natriuretic peptide (ANP) (B)</p> Signup and view all the answers

Flashcards

Tubular Reabsorption

The process where the body takes back substances from the filtrate in the kidney tubules into the blood.

Glomerular Filtration

The initial step in urine formation where water and small solutes are filtered from the blood into the Bowman's capsule.

Tubular Secretion

The process where the kidney tubules actively transport substances from the blood into the filtrate to be excreted.

Trans-epithelial Transport

The movement of substances across the tubule epithelium and into the interstitial fluid, ultimately re-entering the bloodstream.

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Active Transport

A type of transport that requires energy, usually in the form of ATP, to move substances across cell membranes.

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Passive Transport

A type of transport that does not require energy input, relying on concentration gradients or pressure differences.

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Cotransport Reabsorption

The reabsorption of organic nutrients, such as glucose and amino acids, and certain ions through cotransport mechanisms at the apical membrane.

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Water Reabsorption

The process where water moves across the tubule epithelium through aquaporins due to osmotic gradients.

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Aquaporins

Facilitates water reabsorption in the kidneys by creating channels for water to pass through cell membranes.

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Aldosterone

Hormone that increases sodium reabsorption, leading to water retention and increased blood pressure.

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ADH (Antidiuretic Hormone)

Hormone that promotes the reabsorption of water in the kidneys, reducing urine volume and increasing blood pressure.

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ANP (Atrial Natriuretic Peptide)

Hormone that reduces sodium reabsorption in the kidneys, increasing sodium and water excretion to lower blood pressure.

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PTH (Parathyroid Hormone)

A hormone that promotes calcium reabsorption in the kidneys, increasing blood calcium levels.

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Descending Limb

Portion of the nephron where water can be reabsorbed, but solutes are generally not reabsorbed.

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Ascending Limb

The section of the nephron where solutes are reabsorbed, but water reabsorption is limited.

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Study Notes

  • Urine formation involves tubular reabsorption as a key process in the urinary system.

The Solution

  • Blood undergoes glomerular filtration, where it is filtered (without cells or proteins) and the filtrate is dumped into a waste container.
  • Tubular reabsorption involves taking back substances the body needs to keep.
  • Tubular secretion adds substances to the container based on the body's status to keep blood balanced.
  • What is removed from the body as urine undergoes tubular secretion.

Tubular Reabsorption

  • It is a selective trans-epithelial process
  • Almost all organic nutrients are reabsorbed.
  • Water and ion reabsorption is hormonally regulated and adjusted.
  • The processes can be active (requiring ATP) or passive.
  • Sodium potassium pumps are important for tubular reabsorption, assisting in getting substances back into the blood as water follows salt.

Reabsorption Locations

  • Water can leave the descending limb, while most solutes cannot.
  • Solutes can leave the ascending limb, while most water cannot.

Regulatory Factors

  • The body changes reabsorption and secretion to meet the needs
  • Andieuretic hormone (ADH) inhibits urine output.
  • Aldosterone fine-tunes resorption of sodium, after which water follows.
  • Atrial natriuretic peptide (ANP) causes less reabsorption of sodium, decreasing blood pressure.
  • Parathyroid hormone (PTH) controls the rate of sodium reabsorption.

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